Scientists pinpoint the changes that happen when gut bacteria invade the bloodstream
Researchers have pinpointed genotypic and phenotypic changes that take place when colonising bacteria in a patient’s gut invade and infect the bloodstream. The team aimed to determine what changes occur within bacteria in a patient’s gut that enable them to become invasive bloodstream pathogens.
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Clinical considerations for the next pandemic: challenges facing Japan and strategic preparedness
Multiple global pandemics over the past century – the Spanish influenza (1918), Asian influenza (1957), Hong Kong influenza (1968), H1N1 influenza (2009), and COVID‑19 (since 2019) – have increasingly underscored the necessity for healthcare systems worldwide to be resilient, rapidly responsive, and forward‑facing.
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Clear but not clean: the hidden life of drinking water in Nigeria
In many communities across Nigeria, clear water is assumed to be safe. Transparency, both literal and visual, has become shorthand for purity. My recent research in Ede, southwestern Nigeria, began with a simple but uncomfortable question: what are people actually drinking?
Can we make a vaccine against the next Disease X in 100 days?
The COVID-19 pandemic was one of the deadliest events in modern history. Estimated to have killed over 25 million people worldwide and caused trillions of dollars in economic damage, the devastation caused by this virus was both astronomical and unforgettable.
A journey to run a polymerase chain reaction in the kitchen
Did you know an air fryer can thermocycle?
Under the Lens video series
The Microbiologist: Under the Lens | Episode 3
Is raw milk safe to drink? Prof Emmanuel Adukwu is joined by Prof Nicola Holden and Dr Gil Domingue for a conversation on the societal, scientific, and health implications of this pertinent question.
The Microbiologist: Under the Lens | Episode 2
In our second episode, Dr Callum Cooper joins Professor Emmanuel Adukwu to talk about all things bacteriophage, from alternatives to antibiotics, social impact, and regulation.
The Microbiologist: Under the Lens | Episode 1
In our first episode, Professor Raquel Peixoto joins Professor Jack Gilbert for a deep dive into coral reefs, microbes, and the future of our planet.
The Microbiologist: Under the Lens | Episode 3
The Microbiologist: Under the Lens | Episode 2
The Microbiologist: Under the Lens | Episode 1
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Reversing the threat: How to stop measles from spreading again
As the Global Virus Network issues a stark warning over the significant resurgence of measles in the US and globally, William J. Moss, Sten H. Vermund, and Maggie L. Bartlett set out what needs to be done if the preventable harms of the current surge are to be reversed.
Why chromogenic media matters when testing for invasive pathogens: Could the cheapest plate be an expensive decision?
Chris Armstrong, President of Microbiology, Thermo Fisher Scientific, argues that laboratories should stop judging fungal culture media on unit price alone.
Disease X and the limits of voluntary multilateralism
Disease X is less a biological uncertainty than a governance stress test. The real question is whether the WHO Pandemic Agreement has corrected the failures exposed during COVID-19.
From microbial processes to biofilm control: our interview with LAM deputy editor Marciane Magnani
We catch up with food microbiologist Professor Marciane Magnani of the Federal University of Paraíba in Brazil who has just been appointed as a Deputy Editor of Letters in Applied Microbiology.
From one bench to another: Representing early-career scientists at Parliament’s Voice of the Future
Tyler Myers, an MPhil Candidate at the University of Cambridge, reports back from the Royal Society of Biology’s Voice of the Future event at Parliament, where he served as a guest panelist representing Applied Microbiology International.
Q&A: Meet Letters in Applied Microbiology junior editor Daniel Jesuwenu Ajose
We caught up with Daniel Jesuwenu Ajose, a Postdoctoral Research Fellow at the School of Biology and Environmental Sciences, University of Mpumalanga in South Africa, who is one of the newest Junior Editors with Letters in Applied Microbiology
The handbook that can prepare countries for the next pandemic
A new handbook has been published to pave the way for better decision-making and greater preparedness for the next pandemic. It provides practical guidance on how mathematical models can be used to inform decision-making, and how the results can be communicated in times of crisis.
Scientists source anti-cancer treatment in bacteria
Researchers have developed an anti-cancer therapy inspired by bacteria found in cancer tumors. The therapy is made from a fragment of a bacterial protein, a peptide called aurB. In cancer tumors in the animal models, aurB prevented energy production in the tumor cells’ mitochondria, essentially cutting off the tumor’s fuel.
Tracking a persistent threat: How antibiotic-resistant bacteria travel from poultry farms to fresh produce
A new study develops an integrated quantitative microbial risk assessment (QMRA) model to trace the pathway of ESBL-producing E. coli from broiler farms to lettuce consumption, quantifying human health risks and identifying effective intervention strategies.
Food security
Tracking a persistent threat: How antibiotic-resistant bacteria travel from poultry farms to fresh produce
A new study develops an integrated quantitative microbial risk assessment (QMRA) model to trace the pathway of ESBL-producing E. coli from broiler farms to lettuce consumption, quantifying human health risks and identifying effective intervention strategies.
Clean Water
Scientists uncover how pathogens switch on their virulence
A research team has uncovered how a key protein switches on the machinery that enables Leptospira pathogens to survive and cause disease. The findings provide new insights into how pathogens regulate their virulence and may open new avenues for therapeutic interventions.
Crab shell by-products could help regulate the marine lifetime of biodegradable plastics
Researchers show that crab shell by-products can reduce the breakdown rate of biodegradable plastics in seawater by altering the microbial communities that colonize their surfaces, known as the plastisphere.
