All One Health Content – Page 105
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New dual therapeutic strategy shows promise against multidrug-resistant salmonella
A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports. Source: CDC/ Antibiotic Resistance Coordination and Strategy Unit Medical illustration of drug-resistant, nontyphoidal Salmonella sp. ...
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COVID-19 virus can stay in the body more than a year after infection
The COVID-19 virus can persist in the blood and tissue of patients for more than a year after the acute phase of the illness has ended, according to new research that offers potential clues to why some people develop long COVID.
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Study probes what makes a pathogen antibiotic-resistant
Researchers describe how two notable pathogens—Escherichia coli and Acinetobacter baumannii—employ distinctly different tools to fend off antibiotic attack.
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Fibrinolytic biomarkers for identifying patients at risk of severe COVID-19
Researchers identify associations between proteins involved in fibrinolysis and the development of acute respiratory distress syndrome.
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$12.7 million to develop novel nanoalum adjuvant formulation for better protection against tuberculosis and pandemic influenza
The Access to Advanced Health Institute (AAHI) has been awarded the first stage of funding for a $12.7-million project to develop a novel immune-stimulating adjuvant formulation that will improve the human immune response to vaccines.
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Zika virus vaccine emerges as an unlikely hero in battling brain cancer
Scientists have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumour growth, while sparing healthy cells.
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Scientists show how COVID mRNA vaccines reshape immune memory after each dose
Researchers show that T cells can reshape their memory and maintain diversity against different COVID variants in response to successive mRNA vaccinations.
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Women with high-risk HPV and metabolic syndrome have almost three times risk for mortality
Women with both metabolic syndrome and high-risk strains of human papillomavirus (HPV) are at a 2.6 times higher risk for mortality than women without either condition.
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Researchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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Rapid molecular testing in the emergency department leads to faster, targeted treatment for community-acquired pneumonia
Rapid molecular testing for patients hospitalised with suspected community-acquired pneumonia (CAP) significantly enhances the speed and accuracy of treatment.
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Study reveals how virus hijacks insect sperm to control disease vectors and pests
A new study reveals how viral proteins from symbiotic bacteria cause sterility in insects.
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Research reveals novel herpesvirus in South American pinnipeds
Scientists detected Otariid gammaherpesvirus 1 (OtGHV1) in free-ranging South American pinnipeds, and a novel herpesvirus Otariid gammaherpesvirus 8 (OtGHV8) in South American sea lions (Otaria byronia) in the Southern Hemisphere.
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Industrious communities can create cheaters, even in bacteria
These colorful patterns are proof that bacteria and humans aren’t all that different — both harbor individuals that will take the easy way out when given the chance. And that lifestyle can quickly spread to the detriment of all.
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Long-acting HIV treatment benefits adults with barriers to daily pill taking and adolescents with suppressed HIV
Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found safe in adolescents with HIV viral suppression.
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STI cases on the rise across Europe
In 2022, the number of reported cases saw a significant increase compared to the previous year, with gonorrhoea cases rising by 48%, syphilis cases by 34%, and chlamydia cases by 16%.
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First atom-level structure of packaged viral genome reveals new properties, dynamics
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, researchers report.
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Researchers show viral infections pose early heart risks
Myocarditis is often triggered by the body’s immune response to a viral infection, but a new study shows that the virus itself creates potentially dangerous conditions in the heart before inflammation sets in.
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Vaccinated people had lower risk of severe COVID-19 outcomes
Among people who had COVID-19, those who previously received the latest vaccine had a lower risk of having a severe outcome than those who had not, according to new research.
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Malaria parasite generates genetic diversity using evolutionary ‘copy-paste’ tactic
Plasmodium falciparum, a malaria parasite, uses gene conversion to produce genetic diversity in two surface protein genes targeted by the human immune system.
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£1.5m donation drives UK-Japan collaboration in antimicrobial research
A £1.5 million donation will drive joint research into antimicrobial resistance (AMR) by scientists in the UK and Japan.