Human cells may possess a previously underappreciated defence against Ebola virus infection. Researchers found that the cell-surface protein CD81 can restrict viral entry and replication, while Ebola appears to use two of its own proteins to counteract this protective mechanism.
The broadly neutralizing antibody VRC01 has been thoroughly vetted as a potential prophylactic that could prevent people from becoming infected with HIV. A new analysis of data shows that the antibody initially provides strong protection, but that some strains of the virus can still cause breakthrough infections after treatment has stopped.
Researchers have described how they advanced an experimental CRISPR approach for sickle cell disease into a blood stem cell therapy that can be manufactured at the scale and quality required for a clinical trial.
Researchers have created the most detailed map yet of how essential genes interact in Mycobacterium tuberculosis. By uncovering nearly 6,500 genetic relationships, the study reveals hidden gene functions and points to new ways of identifying drug targets and more effective antibiotic combinations.
A new toothbrush generates electricity through bristle movement to wage war on plaque-producing pathogens. The invention successfully reduced cavity- and periodontitis-causing bacteria better than regular mechanical brushing in the mouths of 115 volunteers over 3 months.
A researcher has used his AI-supported Sequence Display technology to expand the targeting abilities of CRISPR/Cas9, evolving several variants of a compact Cas9 that could efficiently target stretches of DNA previously inaccessible for editing. The evolved Cas9s were successfully used to edit two genes found in coronary heart disease.
Human cells may possess a previously underappreciated defence against Ebola virus infection. Researchers found that the cell-surface protein CD81 can restrict viral entry and replication, while Ebola appears to use two of its own proteins to counteract this protective mechanism.
Researchers have described how they advanced an experimental CRISPR approach for sickle cell disease into a blood stem cell therapy that can be manufactured at the scale and quality required for a clinical trial.
Researchers have created the most detailed map yet of how essential genes interact in Mycobacterium tuberculosis. By uncovering nearly 6,500 genetic relationships, the study reveals hidden gene functions and points to new ways of identifying drug targets and more effective antibiotic combinations.
Perpetual Next have signed a License and Engineering Agreement with Air Liquide Engineering and Technologies for the supply of syngas-to-methanol technology for Perpetual Next’s first biomethanol facility, with an option to extend across other biomethanol sites.
AFYREN and Terrial today announce the renewal of their strategic partnership with the signing of a new multi-year fertilizer supply contract, worth several tens of millions of euros This long-term contract strengthens both companies’ commitment to making French agriculture more sustainable and less dependent on international fertilizer markets.
A researcher has used his AI-supported Sequence Display technology to expand the targeting abilities of CRISPR/Cas9, evolving several variants of a compact Cas9 that could efficiently target stretches of DNA previously inaccessible for editing. The evolved Cas9s were successfully used to edit two genes found in coronary heart disease.
Researchers have created a new computational tool that works from an inferred ancestral point and evolves forward to the modern-day genome to trace the insertion and deletion dynamics of these ’jumping genes’, known as transposable elements.
A handful of soil holds a crowded world of bacteria, fungi and other organisms. Scientists can collect their DNA, but much of it remains difficult to identify. Now, researchers have developed an artificial intelligence tool that recognizes bacterial DNA in tiny genetic fragments, making it faster and easier to study the complex communities living in soil.
Environmental microbiologist Professor James Ebdon, from the University of Brighton, UK, has been named as the winner of the John Snow Public Health Innovation Prize, which recognises outstanding achievements in applied microbiology that deliver measurable improvements in public health and environmental health outcomes.
Members of Applied Microbiology International (AMI) have urged the European Commission to put microbial communities at the heart of environmental risk assessments for genetically modified microorganisms, as part of its response to the EU Biotech Act consultation.
At Targeting Microbiota 2026 in Málaga, international scientists will explore how microbiome discoveries can move beyond laboratory research toward evidence-based clinical applications.