Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
Scientists have discovered a new antibiotic that works in a never-before-seen way and may be the next frontliner in the fight against drug-resistant superbugs.
Read storyA study demonstrated that the evolution of a single species can alter the composition of an entire species community. The study monitored a microbial community composed of 23 bacterial species for four years. Researchers analysed the community’s species composition and changes in bacterial genomes.
Fiber is an essential part of a healthy diet. By eating a variety of plant-based foods, increasing fiber intake gradually and staying well hydrated, you can support gut health and overall well-being while making fiber goals more achievable and sustainable. Purna Kashyap, M.B.B.S., a gastroenterologist at Mayo Clinic in Rochester, ...
A new study has found that the common sexually transmitted infection, Mycoplasma genitalium, also known as MGen, does not appear to increase the risk of recurrent preterm birth. Earlier research suggested that certain Mycoplasma species might contribute to preterm labor, but those studies were limited.
A new study indicates greater wax moth larvae show great potential as a robust and ethically acceptable in vivo model for studying pathogenic bacteria.
Microbe DNA from ancient dental calculus offers insights into the past oral microbiomes of the Japanese people, including the phylogeny of the periodontal disease-associated archaeon, Methanobrevibacter oralis.
A new study indicates resistance to antimicrobial agents is rising among human infections with Shiga toxin–producing Escherichia coli bacteria.
A new study found that AI chatbots made vaccine-hesitant parents more likely to say they would vaccinate their children against HPV, but did not outperform materials from government health agencies, whose effects also lasted longer.
Funded by the Global Health EDCTP3 Joint Undertaking, a new €15.3 million project coordinated by Institut Pasteur brings together seven partners across four continents to advance clinical trials and prepare for the manufacturing of a chikungunya vaccine in Africa.
A research team was awarded a 5-year, $3.8 million grant to study early immune responses in the lung and how they influence tuberculosis infection outcomes. The program focuses on how lung immune cells called macrophages influence the earliest stages of tuberculosis infection.
A first-in-human study shows that a handheld probe placed gently on the belly of most fragile infants can reliably identify early stages of necrotizing enterocolitis.
A study based on blood samples strongly suggests that most persistent cases of viral detection, despite ideal HIV drug therapy, are not due to virus transmission or a rebound of active disease.
Researchers recently studied associations among green space exposure, mental well-being, and the nasal microbiome—the microbes in a person’s nose. The analysis showed correlations among microbial signatures, time spent outdoors and positive mental well-being.
A new study shows that food insecurity may leave a measurable impact on the gut microbiome of children. Children in food-insecure households had different gut microbiome profiles, including higher levels of Sutterella, which has been linked to poor dietary quality and intestinal inflammation.
Researchers have assessed long-term trends in TORCH infections in India, a region where reliable data have been lacking. TORCH includes pathogens that cause toxoplasmosis, rubella, cytomegalovirus (CMV), herpes simplex virus and other infections.
A new study shows that sewage overflows in homes can expose people to bacteria that can make them sick, including antibiotic-resistant and multidrug resistant bacteria which can make infections difficult to treat.
Infections should be considered a “health hazard” in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but under-recognised burden of illness, hospitalisation and death. People living with type 1 diabetes, type 2 diabetes and prediabetes face higher risks of infection compared to those without diabetes.
The genetic diversity of hantavirus and the low levels of virus typically found in patient samples make sequencing its genome particularly challenging. Researchers have developed a new, effective, and low-cost way to carry out whole genome sequencing for hantaviruses.
To rebalance the oral microbiome and cure chronic halitosis, researchers are embarking on a first-of-its-kind experiment. These clinical trials transplant bacteria and other microbes from healthy donors into patients with halitosis. If successful, the healthy microbiota will crowd out the bad and patients’ bad breath will improve.
A study has found that vaccination against respiratory syncytial virus (RSV) during pregnancy reduced the risk of hospitalization in young infants by nearly 70%. It provides early real-world evidence from U.S. clinical care, showing that administering one dose of the maternal RSV vaccine (RSVpreF vaccine) reduces hospitalization related to RSV in young infants.
A class of flu drugs may reduce cognitive decline and premature aging in people living with chronic viral infection. Scientists identified a new biological culprit: the degradation of protective sugar molecules in our bodies, known as glycans, that normally help keep inflammation in check.
The DIVINE study database has been published. The cohort includes clinical information from 5,813 patients hospitalised with COVID-19 during four waves of the pandemic, between March 2020 and August 2021, across five hospitals in the southern metropolitan area of Barcelona.
A new study reveals that when the difference between body temperature and the ambient temperature is greater, the clouds of particles generated by coughing or sneezing disperse more and maintain a higher concentration.