One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
AI could transform how laboratories detect rabies
Researchers have developed a world-first AI system that can detect rabies virus infection in cell cultures and measure protective antibody levels with high accuracy. The approach could make laboratory testing faster, more consistent and more accessible in countries where rabies remains endemic.
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NewsSalicylic acid helps apples fight blue mould after harvest
A natural plant signalling compound could help apples fight one of their most common storage diseases. Researchers found that salicylic acid slowed blue mould development while reshaping the fruit’s phenolic metabolism, revealing chemical changes that may help explain how apples resist fungal decay.
NewsStudy maps antimicrobial resistance across major drinking water sources
Rivers, reservoirs and lakes can act as reservoirs for antibiotic residues and antimicrobial resistance, but the risks are not evenly distributed. A new study of drinking water sources in the Poyang Lake basin found that rivers and certain lake sites carried higher resistance-gene burdens, with mobile genetic elements emerging as a key factor linked to their spread.
NewsMachine learning links water quality measurements to potential pathogen risks
A study of drinking water prediction systems shows that environmental measurements could support predictions of multiple microbial targets and generate potential health risk estimates broadly consistent with calculations based on measured pathogen concentrations.
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WHO welcomes adoption of United Nations political declaration on pandemic prevention, preparedness and response
The World Health Organization (WHO) has welcomed the adoption by the United Nations General Assembly (UNGA) of the Political declaration on pandemic prevention, preparedness and response (PPPR).
News‘Molecular movie’ captures penicillin being built atom by atom
Scientists have captured the formation of penicillin’s defining β-lactam ring in unprecedented detail, revealing fleeting chemical steps that had remained hidden for decades. Using ultrafast X-ray imaging, the researchers built a molecular movie of the reaction that could help guide future antibiotic and enzyme design.
NewsMalaria remains the leading cause of hospital admission and in-hospital death in children under two in Sierra Leone
Malaria remains the biggest threat to young children in Sierra Leone, accounting for more than half of hospital admissions in a large two-year study. Researchers also found that children who received all routine vaccinations and preventive malaria treatment had a substantially lower risk of dying.
NewsA natural compound takes aim at C. difficile while sparing the gut microbiome
Researchers identify argyrin B, a promising natural compound that targets the bacterium behind dangerous intestinal infections while leaving beneficial gut microbes largely unharmed. The discovery could pave the way for new treatments with fewer relapses and side effects.
NewsPeople with long Covid have drastically different microbiome in their lungs and mouth
A study of more than 700 people has shown that those with long Covid have distinct differences in the mix of bacteria that live in their mouths and lungs, according to a study. The research also shows that these differences in the lung microbiome are linked to respiratory symptoms, as well as the cognitive and digestive problems known to occur in long Covid.
NewsA self-disinfecting fabric eliminates bacteria, fungi and viruses in hospital settings
Researchers have developed a new self-disinfecting cotton fabric capable of eliminating bacteria, fungi and viruses in hospital settings using visible light. The material incorporates two photoactive compounds which, when exposed to light, generate a highly reactive form of oxygen that damages the microorganisms adhering to the fabric.
NewsFrom warning signals to action: Closing a critical gap in infectious disease preparedness
Between the first sign of an unusual event and an effective public health response lie several critical steps: verifying the signal, identifying the pathogen, assessing the risk, making a decision, and translating that decision into action. A new Perspective asks: how can infectious disease risk assessment better support timely and actionable public health decisions?
NewsCould a vaccine adjuvant help prepare for future pandemics?
A study in mice shows that K3-SPG can activate innate immunity, offering potential temporary defense against respiratory viruses while vaccines are developed.
NewsValue-aligned messages increased COVID-19 vaccination intentions, study finds
Vaccine-hesitant adults were more likely to consider getting a COVID-19 vaccine when public health messages acknowledged distrust of government and affirmed values such as personal liberty, a new study found.
NewsFungi that colonise human faeces: first scientific study lays the groundwork for myco-sanitation
Filamentous fungi can colonise fresh human faeces, and the choice of fungal species shapes how the material changes, according to a new study. Depending on the species, the fungi accelerated degradation, reduced faecal indicator bacteria, suppressed faecal odour or changed the appearance of the material.
NewsA newly discovered membrane defence help explain antibiotic resistance in Pseudomonas aeruginosa
Scientists have uncovered how Pseudomonas aeruginosa, a major multidrug-resistant superbug, helps block antibiotics from entering its cells. The study identifies two proteins that act like plugs inside a membrane channel, revealing a potential new target for treatments designed to weaken bacterial defenses.
NewsUniversity of Stirling secures £2.4M grant for major aquaculture project
Antibiotic resistance is becoming an increasing challenge for Vietnam’s vast pangasius catfish industry, where farmers often have few practical alternatives when treatments stop working. A new £2.4 million project will bring scientists, farmers and policymakers together to develop more sustainable ways to control disease and reduce reliance on antibiotics.
NewsWhat makes hantaviruses jump from rodents to humans?
Why do some hantaviruses jump from rodents to humans while others remain largely confined to wildlife? A new study will combine viral genetics, climate data and wildlife ecology to uncover the conditions that drive spillover and help identify where future outbreaks are most likely to emerge.
NewsPooling samples could expand TB testing worldwide
Testing sputum samples in small groups could nearly double access to rapid tuberculosis diagnosis without doubling costs. The largest study of pooled TB testing found that the approach cut molecular test cartridge use by 51%, helping inform new WHO guidance for resource-constrained settings.
NewsA ‘society on a chip’ reveals how viruses spread
Researchers have built a centimetre-scale ‘society on a chip’ that recreates how viruses spread through structured populations. By changing cell density, susceptibility and movement, the platform can mimic transmission, social distancing and even herd-immunity-like effects in real time.
NewsCommon airway bacterium may help prepare lungs to fight pneumonia, study finds
A study found that exposure to Prevotella melaninogenica, a type of bacteria commonly found in healthy airways, changed the behavior of immune cells in the lungs of mice. When the mice were later exposed to Streptococcus pneumoniae, a leading cause of bacterial pneumonia, their immune systems were better able to recognize, engulf and clear the bacteria.
NewsThe benefits of vaccination extend beyond protection from infection
A study, carried out in mice, shows how after recovering from an acute viral infection, animals experienced a long period of impaired immune responsiveness which compromised their immune system’s ability to effectively respond to future challenges. Prior vaccination prevented these detrimental consequences, preserving immune function.
NewsGut microbes across continents trace ancient human migration
A new study has attempted to answer the question of whether homo sapiens hosted a characteristic and diverse microbiome going back millennia. Gaining insight into which, if any, long-term residents of the microbiome co-evolved with humans could point to ways to investigate how the loss of microbial diversity through industrialization impacts human biology.
NewsStudy may explain why IBD patients react to foods they once tolerated
A new study finds that gut inflammation can change the way gut bacteria break down food — possibly triggering immune reactions to foods that were previously fine to eat. The findings may help explain why so many people with inflammatory bowel disease (IBD) react badly to foods like dairy or gluten, even in remission.