One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Vanderbilt Center for Antibody Therapeutics signs agreement to develop anti-measles antibody treatment
The Vanderbilt Center for Antibody Therapeutics has signed an option agreement with Saravir Biopharma Inc. for the company to develop human monoclonal antibodies isolated in the laboratory of James Crowe Jr., MD, for the treatment and prevention of measles.
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NewsNipah virus hijacks host protein NSUN2 to fuel replication
Researchers have decoded a critical survival strategy of the deadly Nipah virus (NiV), identifying a key host protein hijacked by the pathogen and translating this discovery into a promising new treatment approach.
NewsInterferon therapy found to be well-tolerated in compensated hepatitis B cirrhosis
A multicenter analysis of 920 patients finds no higher risk of serious complications in compensated cirrhosis compared to standard treatment.
NewsOne of cholera’s great enemies is found in the human gut
Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study. Researchers found that in the Ganges Delta, cholera bacteria rapidly gain and lose special armour that protects against attacks from the virus, known as bacteriophage ICP1.
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News
Oregano, rosemary and ‘time’: Long-term swine study shows natural-compound benefits
In a rare long-term public study that compared the effects of phytochemicals from rosemary and oregano with antibiotic growth promoters, animal scientists found that the natural agents given to weaned pigs supported favorable gut health and growth performance later in their lives.
NewsScientists warn antibacterial soaps and wipes can fuel antimicrobial resistance
An international team of scientists is warning that everyday antibacterial soaps, wipes, sprays, and other “germ‑killing” products are quietly contributing to the global rise of antimicrobial resistance (AMR) while providing no added health benefit for most consumer uses.
NewsRisk of Alzheimer’s dementia significantly reduced after high-dose influenza vaccination compared to the standard dose
The risk of Alzheimer’s disease significantly decreases in older adults who receive a higher dose of the influenza vaccine compared to the standard dose, according to new research.
NewsCommon virus plus mono associated with increased risk of MS
Having the disease infectious mononucleosis, often called mono, caused by the Epstein-Barr virus is associated with an increased risk of developing multiple sclerosis (MS), according to a study.
NewsInfluence of antibiotic use on mental health during pregnancy
New research points to an association between antibiotic exposure and maternal psychological distress in early-to mid-pregnancy.
NewsAir surveillance reveals hidden reservoirs of antibiotic resistance genes
The air we breathe serves as a silent vector of antimicrobial resistance, calling for the need to integrate air monitoring into global public health strategies, according to a review by an international team of researchers.
NewsSmall intestinal bacterial overgrowth - and your allergy symptoms
A review suggests that small intestinal bacterial overgrowth (SIBO) may be associated with symptom exacerbation in atopic diseases, such as bronchial asthma, food allergies, or chronic urticaria.
NewsGlobal Virus Network launches expanded “Global Guardians for Pandemic Preparedness” program for Florida high school students
The Global Virus Network (GVN) announced the launch of its expanded Global Guardians for Pandemic Preparedness initiative, with applications now open for high school students across the state of Florida.
NewsDecoding the chemical messengers: Gut microbes talk to the whole body through metabolites
A comprehensive review systematically maps how bacterial metabolites shape immune responses and diseases across organs.
NewsInequalities in childhood pneumococcal vaccine uptake persist in England despite schedule change
Vaccine uptake data has been examined to assess the impact of moving from a ‘2+1’ to a ‘1+1’ Pneumococcal Conjugate Vaccine (PCV) dose schedule on vaccine coverage and health inequalities among infants in England.
NewsThe tumor microbiota: A new frontier in cancer biology
A new study synthesizes evidence from different types of tumors, particularly those characterized by low microbial biomass, where conclusions require particularly rigorous validation. By outlining a roadmap of experimental and analytical standards, this work provides the basis for more robust research.
NewsScientists develop therapeutic, nasally delivered DNA vaccine for tuberculosis
Research shows the vaccine — in combination with drug therapy — accelerated a relapse-free TB cure in mice, improved activity of a drug-resistant TB regimen and stimulated immune responses in nonhuman primates.
NewsLong COVID associated with increased risk of cardiovascular disease
People with long COVID are at increased risk of developing cardiovascular disease, according to a new study. Women with long COVID had just over twice the risk of receiving a cardiovascular diagnosis compared with women without long COVID. Men had approximately a third higher risk.
NewsSimple blood test for gut bacteria metabolites could spot dementia years earlier
Scientists have discovered that subtle changes in the blood may reveal the earliest signs of cognitive decline long before symptoms become obvious.These changes are caused by chemicals produced by gut bacteria - reinforcing the idea that the gut–brain connection plays an important role in early memory changes.
NewsIntroducing environmental microbiota to urban homes shifts the indoor microbiome
Introducing forest soil on an entryway doormat shifted the indoor microbiome of Finnish homes closer to bacterial profiles found outdoors, with less contribution from human-associated bacteria, a new study shows.
NewsThesis confirms algae have strong wound-healing, skin-protective, and immune-supporting properties
New research demonstrates that polysaccharides extracted from various seaweeds and freshwater cyanobacteria possess remarkable bioactive properties and can accelerate wound healing, reduce inflammation, and protect skin cells from UV-induced damage.
NewsWorld-first discovery of noma-linked bacteria opens path to early diagnosis and prevention
Researchers have identified a bacterium strongly associated with noma disease, marking a major step towards earlier diagnosis and more effective treatment. They uncovered a previously undescribed species of Treponema bacteria, which may be responsible for the disease.
NewsWastewater harbors high-risk antimicrobial resistance genes
Researchers found evidence of genetic material from two major bacterial groups, commonly known to exhibit high-risk resistance profiles, in wastewater samples from a large South Africa city.
NewsMissing gut bacteria may prevent some people with celiac disease from fully benefiting from high-fiber supplements or diets
Many people with celiac disease are advised to eat more fibre to support digestion and manage symptoms, either through diet or prescribed fibre supplements. New research shows that the benefits of that fibre may depend on whether the right bacteria are present in the gut to break it down.