One health

Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.

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Ebola preparedness needs to move beyond a single virus species

Decades of Ebola preparedness have produced vaccines, diagnostics and treatments, but many were built primarily around Zaire ebolavirus. A new perspective argues that future preparedness should span the wider ebolavirus genus, combining broader diagnostics, multivalent vaccines, conserved therapeutic targets and continuous genomic surveillance.

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Bacterial lipa gene linked to stronger virulence and immune disruption in catfish

A bacterial metabolic gene may help Plesiomonas shigelloides become more damaging during fish infections. Increasing lipa expression strengthened bacterial attachment and biofilm formation, worsened disease symptoms in catfish and triggered substantial changes in the host immune response.