One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
What low vaccination rates in the US could mean for flu season 2026
Experts reveal what to expect this flu season, when to get the flu shot, how to recognize flu symptoms, how to treat it, and what the newly approved mRNA flu vaccine means for the public.
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NewsWhen antiviral defense and autoimmunity collide: New insights into lupus genetics
Researchers have found that a common lupus-associated genetic variant may strengthen antiviral immune responses while increasing the risk of autoimmunity.
NewsThe Wistar Institute wins $15M+ NIH investment to advance HIV cure research strategies
The Wistar Institute has announced the National Institutes of Health (NIH) has awarded two major grants totaling more than $15M to Luis J. Montaner, D.V.M., D.Phil., director of Wistar’s HIV Cure and Viral Diseases Center.
NewsPaper reveals huge enthusiasm for Caribbean microbiome hub at inaugural symposium
Turnout at a recent symposium has confirmed the appetite for a new microbiome hub in Puerto Rico, reveals Puerto Rico AMI Global Ambassador Dr. Filipa Godoy-Vitorino.
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Professor Jack Gilbert leaves a lasting legacy of collaboration and global engagement at AMI
As Professor Jack Gilbert steps down as President of Applied Microbiology International, he leaves a legacy of collaboration, generosity and an unwavering commitment to strengthening our global community.
NewsThese bacteria can change their diet to survive inside the body
The team have found that Staphylococcus aureus can adjust its diet depending on what sources remain available. The bacterium can adjust its inner workings in response to any one of a number of different sulfur-containing compounds — like cysteine, glutathione or thiosulfate.
NewsResearchers discover highly potent compound that blocks Ebola virus entry
A research team has discovered a highly potent small molecule that blocks Ebola virus entry by stabilizing the virus’s entry protein and provides strong protection when given orally in a preclinical model. It is more than 100 times more potent than previously reported Ebola entry inhibitors.
NewsC. diff coordinates threat response to survive in gut
Researchers have discovered a unique system C. diff uses to simultaneously sense and respond to two different threats: host-mediated nutrient deprivation and a microbiota-produced antibiotic compound, suggesting new therapeutic options for preventing and treating C. diff infections.
NewsEngineering bacterial surfaces with glucan nanofilms creates a potent vaccine platform against invasive fungal infections
A research team has developed a synthetic bacterium-based vaccine platform that uses engineered bacterial surfaces to assemble glucan nanofilms for enhanced antifungal immunity against pathogens such as Candida albicans.
NewsGut, airway and tumor microbes emerge as promising predictors of immunotherapy response in lung cancer
A comprehensive review systematically evaluates the microbiome’s role in lung cancer immunotherapy. Authors synthesized evidence covering microbial communities in the oral cavity, airways, lung tumors and gut, and their connections to treatment efficacy and immune‑related adverse events.
NewsThousands of new findings contribute to a global virus map
An extensive study has mapped RNA viruses in a large number of cities around the world. The researchers identified nearly 55,000 different types of virus, the vast majority of which had never been observed before. The virus atlas could be useful in both biological risk assessment and crime scene investigations.
NewsFusobacterium nucleatum drives immunosuppression and metastasis in TNBC
A new study identifies Fusobacterium nucleatum, a Gram-negative anaerobic bacterium associated with several cancers, as a key driver of tryptophan metabolic reprogramming, immunosuppression and lung metastasis in triple-negative breast cancer.
NewsA pan-sRNome analysis identifies novel regulatory small RNAs involved in Pseudomonas aeruginosa virulence
A characterization of nine newly discovered sRNAs reveals their regulatory networks in quorum sensing, biofilm formation, and interbacterial competition in Pseudomonas aeruginosa.
NewsExpert consensus outlines 12 recommendations to prevent secondary mucormycosis after respiratory viral infections
The recommendations focus on defined high-risk patients, early viral testing and treatment, hospital infection control, and practical measures for resource-limited settings.
NewsNew study details the finding of the first known live kissing bug in Europe
Students taking a Medical Entomology class donned their detective hats and helped investigate what appears to be the first documented live kissing bug in Europe.
NewsNew research offers avenue to explore relationship between Alzheimer’s and HIV
Researchers have created an animal model that helps resolve questions about the relationship between HIV and Alzheimer’s disease (AD). The virus that drives the root cause of AD initiates a complex chain that, with other disease partners, drives nerve cell injury and cognitive impairments for AD pathology.
NewsSymposium commemorating the 50th anniversary of the discovery of the Hantaan virus successfully held
A symposium commemorating the 50th anniversary of the discovery of the Hantaan virus celebrated the historical achievement of the late Dr. Lee Ho-wang and reviewed the historical significance of Hantaan virus research, its results, and future infectious disease response strategies.
NewsHeatwaves inhibit antibiotic resistance in soils - but at a price
Heatwaves temporarily reduce the amount of resistance genes in the soil, but heat and droughts are also causing significant damage to soils and ecosystems. The temporary dip in resistance therefore does not mean that the health risks from antibiotic resistance disappear.
NewsProbiotic use surges - but microbiome-supportive food consumption stagnates
New research finds that probiotic supplement use has surged in the United States, while the consumption of microbiome-supportive foods has remained virtually unchanged.
NewsToxic tail: Biologists find a hidden weak spot in how bacteria build the tails they use to move
New research has uncovered a previously unknown vulnerability in how bacteria build the whip-like tails they use to move. Building these tails can put stress on the protective wall surrounding a bacterial cell, and uncovered systems bacteria use to keep that stress from becoming destructive.
NewsHelicobacter pylori exposure may be linked to more than 1 in 5 bowel cancer cases worldwide
Exposure to the stomach microbe Helicobacter pylori may be associated with more than 1 in 5 cases of bowel cancer worldwide, suggests an exploratory risk attribution study - and those born in more recent decades may be more at risk of the disease after exposure.
NewsBacterial trial fails to demonstrate early asthma prevention - prompting rethink of 'hygiene hypothesis'
A national clinical trial has found that treating young children with an oral bacterial extract did not reduce the risk of severe wheezing and respiratory illnesses that can precede asthma, potentially prompting researchers to rethink aspects of the hygiene hypothesis.