One health

Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.

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‘Raman barcodes’ can distinguish 20 SARS-CoV-2 variants

Viruses may carry a molecular ‘barcode’ hidden not just in their genetic sequence, but in the way their RNA folds and vibrates. Researchers have used Raman spectroscopy to distinguish 20 SARS-CoV-2 variants and subvariants, pointing towards a potentially faster way to screen emerging viral strains.

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    Scientists ‘crank up’ cells’ natural defence against viruses

    Researchers have found a way to amplify one of the body’s natural antiviral defence pathways, making cells significantly more resistant to infection. By boosting signalling through the protein ISG15, the approach could lead to host-directed treatments that remain effective even as viruses mutate.

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    Research to uncover hidden life cycle of bacteriophages

    Some bacteriophages can quietly replicate inside bacteria for generations without killing their hosts, making these infections difficult to detect with standard methods. A new research project will investigate this hidden life cycle and explore whether understanding it could help scientists engineer more effective phage therapies against drug-resistant infections.

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    Advanced air purification fails to reduce surgical infections

    Cleaner operating-room air may not be enough to prevent surgical infections. In a study of more than 110,000 procedures, advanced air-purification systems did not reduce infections, complications or deaths, suggesting hospitals may gain more by targeting direct contamination of surgical wounds.

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Cranberry juice may be a boon for oral hygiene

Pure cranberry juice may do more than add a tart kick to the holiday table. In a small human study, it slowed dental plaque growth and reduced acid production, suggesting the fruit’s natural compounds could help protect tooth enamel.