Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
Ebola virus can survive unnoticed in the human body for months or even years, hiding in areas with little immune surveillance like the central nervous system. Using a cerebral organoid model, researchers have gained valuable insights into the mechanisms of Ebola virus persistence.
Read storyContinuous consumption of foods containing heat-inactivated Lactiplantibacillus pentosus can help reduce gum bleeding, report researchers. These postbiotic foods can improve inflammatory conditions and enhance gum health in adults with mild gingivitis.
A tiny parasite-carrying tick is posing an outsized threat to Missouri’s cattle. Now, researchers are stepping in to protect the state’s $4 billion cattle industry by tracking different ways the American dog tick spreads a deadly disease known as bovine anaplasmosis.
A new study investigates how the Green View Index (GVI) relates to the richness and diversity of bacteria in the Taipei metropolitan area in Taiwan. The more vegetation in the area, the richer its microbial community.
An international research team has succeeded in designing large-scale protein structures that faithfully replicate the self-assembly principles found in naturally occurring viruses, using artificial intelligence (AI).
The bacteria enterotoxigenic E. coli and Shigella together cause hundreds of millions of infections each year and are among the leading causes of diarrheal death, especially in children. A shared biological feature of these gut pathogens could lead to a vaccine that protects against both.
An AI-enabled antibiotic discovery proves effective at identifying new chemical structures and targets in the constant fight against antibiotic-resistant gonorrhea.
An orange-colored yeast species isolated from a Baltimore sidewalk several years ago could be the basis of eco-friendly mosquito traps that reduce malaria transmission, according to a new study.
Plague outbreaks dating back to around 5,500 years ago documented in hunter-gatherer communities from southeast Siberia are described in a paper. The findings, based on an analysis of ancient DNA, may be the oldest known evidence of the plague and could shed light on its origins.
New research suggests that cow’s milk has the edge over plant-based alternatives when it comes to bone strength and nutrient absorption.
New research shows that temperatures in the tropical Atlantic and Indian Oceans drive year-to-year changes in malaria cases in Malawi.
The microbiome of ancient middens in Greenland sheds new light on the daily life of Paleo-Inuit and old Norse communities. Researchers say the middens in the cold Arctic acted like long-term natural experiments, with human- and animal-associated bacterial signals remaining detectable many centuries later.
Capnocytophaga canimorsus is a bacterium found in the mouths of dogs and cats. It can cause severe sepsis, and in some cases leads to purpura fulminans (PF), a condition that triggers rapid tissue necrosis.
A study investigating the effects of prebiotic xylo-oligosaccharides (XOS) on fatty liver in humans suggest that the fiber supplement may reduce harmful metabolic byproducts in the gut and improve liver health. The composition of the gut microbiota prior to supplementation influences the benefits observed.
Researchers have uncovered previously unknown relationships between bacteriophages and their bacterial hosts. They found a previously unreported group of bacterial hosts for the well-studied bacteriophage P1 and examine how subtle changes in viral structure influence which microbes a phage can target.
A new biochar supported cobalt oxide catalyst rapidly removes levofloxacin from water while revealing a key reaction mechanism for cleaner wastewater treatment.
In a pilot clinical trial that included older adults with depression receiving standard care, adding probiotic therapy produced modest but meaningful reductions in depressive and anxiety symptoms compared with adding a placebo. However, both groups demonstrated substantial overall improvements during follow-up.
Jacques Ravel, professor at the University of Maryland School of Medicine and leader in human microbiome research, has been named by the One Health Microbiome Center as the second laureate of the Microbiome Medal.
University of California, Irvine immunologist Lbachir BenMohamed has been awarded a $3.93 million National Institutes of Health grant to develop and test a novel therapeutic vaccine designed to prevent recurrent genital herpes.
A new investigation into the links between Alzheimer’s disease and the gut microbiome in Puerto Rico has found specific gut microbial patterns associated with cognitive decline, disease severity and genetic risk factors.
Researchers explore the effectivity of new therapeutic cancer vaccine in preventing the recurence of human papillomavirus triggered cancers.
In temperate regions, flu season is in the winter, while in the tropics, constant low-intensity activity is typically punctuated by two annual peaks—or a surge during the rainy season. Researchers investigated whether specific humidity—the mass of water vapor per unit mass of air—could explain these differing patterns.
A growing global debate over “biopiracy” is raising urgent questions for microbiologists, researchers, industry and policymakers alike — and Applied Microbiology International is calling on members to help shape the conversation.