One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Fleming Initiative selects AWS to power global intelligence platform to tackle antimicrobial resistance
The Fleming Initiative has received support from Amazon Web Services (AWS), including up to several million pounds worth of cloud and AI technology, as well as technical support, for the Initiative’s global antimicrobial resistance (AMR) intelligence platform.
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NewsDeep-sea extremophile yields protein that forms super stable biofilm
Scientists have discovered a protein secreted by a deep-sea extremophile — an organism adapted to extreme environmental conditions — that self-assembles into a biofilm and is highly stable, boosting its potential for biomedical applications.
NewsBiomarkers may someday help clinicians better detect Borrelia burgdorferi infections
Current tests for Lyme disease often miss infections during the early critical window and cannot tell whether bacteria are still present or were cleared years ago. New research suggests that anti-lipid antibodies may address these shortcomings.
NewsTick-borne diseases reported every month of the year and in every Illinois county
A new analysis of state health department data reveals that more than 6,400 Illinois residents were diagnosed with tickborne diseases from 2004-2022.
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News
Scientists probe how proteins are inserted into cell membranes
Researchers looking at the cell membrane investigate how the proteins manufactured by the ribosomes in the cell interior reach their position within the membrane in the correct form and when the processes became established over the course of evolution.
NewsAntibiotics reverse damage caused to blood stem cells by chronic Salmonella
A new study has revealed that long-term Salmonella infections severely damage blood stem cells - but this damage is completely reversible. Giving an effective course of antibiotics fully restores the stem cells, allowing them to recover their health and rebuilding power.
NewsBack in action: Researchers make drug-resistant bacteria vulnerable again
New findings show that disabling a single bacterial protein can restore vancomycin’s power against resistant bacteria – and point to a new strategy for overcoming antibiotic resistance.
NewsViruses under stress: how viral shells change shape as they dry out
New research explores the structural dynamics and conformational changes of bacteriophage MS2 capsids under conditions of dehydration.
NewsIntestinal cells found to starve Salmonella of essential nutrients, revealing new tactic in infection defense
A new discovery sheds light on how the human body controls Salmonella infections and opens pathways for potential treatments for Salmonella and other food-borne infections.
NewsScientists uncover the hidden air risks in university cafeterias
By assessing two university cafeterias, a new study has shown that both sites had elevated temperature and PM10 levels, while one also showed high carbon dioxide and the other high total bacterial counts.
NewsDiabetes worsens long COVID complications
In a study involving 870 participants, people with diabetes took longer to recover from the virus and experienced more severe cardiac complications, as well as greater physical and cognitive difficulties.
NewsCryo-EM helps identify the mechanisms of dental plaque formation
Researchers used cryo-electron microscopy to provide new insights into how Porphyromonas gingivalis causes plaque formation, revealing the 3D structure of Mfa pili, an arm-like filament which enables the bacteria to stick to host tissues and other microbes.
NewsResearchers affirm long-held belief that viruses can trigger Parkinson’s disease
Researchers have developed a model that uses a nontoxic way to generate the symptoms of Parkinson’s: infection with a virus. It proves that a simple viral infection can trigger the exact brain damage and physical disabilities in animal models that are seen in people with Parkinson’s disease.
NewsSame day administration of COVID-19 and influenza vaccines not associated with increase in adverse events
A target trial emulation found that same day coadministration of the COVID-19 and influenza vaccines was not associated with a higher risk of serious or clinically meaningful adverse events compared with receiving only an influenza vaccine.
NewsCase study: Fatal rabies in a child
Ontario’s first case of fatal rabies since 1967 provides critical guidance to help prevent death from rabies in future instances. The parents agreed to share their son’s case to help raise awareness of rabies.
NewsA 'copper economy' helps fungi and bacteria build better biofilms
Scientists have discovered that two common human pathogens can work together by managing copper in their shared environment - a finding that could open new ways to break down stubborn mixed biofilms.
NewsHantavirus in the South Atlantic: A one health and microbiome wake‑up call
The hantavirus pulmonary syndrome outbreak on MV Hondius shows how global travel and environmental change are reshaping how zoonotic viruses emerge. In a new commentary, Professor Lu proposes four initiatives aligned with Microbiome and One Health.
NewsMount Sinai scientists develop first fully human monoclonal antibody cocktail that protects against Nipah and Hendra viruses
New preclinical study demonstrates that a novel monoclonal antibody cocktail provides complete protection against lethal Nipah and Hendra virus infection.
NewsProbiotic bacteria Lactobacillus rhamnosus alleviates diabetic nephropathy in rat models
A recent study demonstrates that the probiotic strain Lactobacillus rhamnosus exerts significant renoprotective effects rat models of diabetic nephropathy.
NewsSea anemone flips a human antiviral strategy on its head
A new study has uncovered a previously unknown antiviral defense mechanism in sea anemones, revealing that animals may have evolved more than one way to fight viral infections.
NewsNew research makes critical discovery for the global fight against antibiotic resistance
A study has found that an unusual pairing of two commonly used antibiotics can kill and stop the spread of resistance in a highly drug-resistant bacterium, Pseudomonas aeruginosa.
NewsClimate change could reshape flu seasons across the Americas
Researchers find that weather and climate patterns can help predict the timing and severity of flu outbreaks across diverse regions.
NewsGut microbiome could hold important clues as to how IBD develops and progresses
The gut microbiome could hold important clues as to how IBD develops and progresses – and which treatment is best suited to individual patients.