Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
An international research team has uncovered compelling evidence that gut-microbe-derived molecules may play an important role in shaping the developing immune system during early childhood.
Read storyTwo studies describe how researchers found a novel CRISPR mechanism, Cas12a2, in a family of nucleases that exclusively cleave DNA. In contrast, Cas12a2 was able to broadly cleave both RNA and DNA.
Vaccinating women during pregnancy leads to the transfer of antibodies to their newborns. These antibodies were detected not only in blood, but also in the nasal mucosa, the site where whooping cough bacteria enter the body.
Researchers have determined how our immune systems fight back against the parasite Toxoplasma gondii when it makes it inside the CD8+ T cells meant to destroy it.
A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how the disease progression and patient outcomes.
A clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.
A new study reveals that environmental stressors do not merely kill bacteria; they can also prime surviving cells to take up resistance genes more efficiently, raising concerns about how antibiotic-resistant bacteria may spread in aquatic environments.
Researchers have uncovered several new mechanisms by which antibodies block E. coli bacteria that cause urinary tract infections from attaching to bladder cells. Once E. coli bacteria get a strong grip, they can be difficult to flush out.
Using ribosome engineering (RE), researchers introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG). These mutant LGGs exhibit altered surface protein expression, including increased presentation of so-called “moonlighting proteins.”
A study demonstrates that plant-derived phenolic acids can act as powerful antibiotic adjuvants by restoring and enhancing tetracycline efficacy against multidrug-resistant bacteria through multi-target disruption of key resistance mechanisms.
Researchers report newly discovered details about the Cas12a3 immune system that precisely targets transfer RNA in invading pathogens, without destroying host cells.
Researchers have identified a molecule that may help turn the tide on fungal infections — butyrolactol A, a chemical compound that targets a deadly, disease-causing fungi called Cryptococcus neoformans.
Researchers propose the concept of infection-driven senescence (IDS) to describe the phenomenon in which microbial agents, beyond viruses, can trigger cellular senescence in host cells.
An international panel of experts from 32 countries has presented specific antimicrobial stewardship standards for TB care for the first time.
A recent study has revealed a novel cancer-promoting mechanism of Streptococcus anginosus. The research shows that methionine metabolites produced by this bacterium can significantly contribute to the development of gastric cancer.
A new database targeting chronic urinary tract infections (UTIs) – a long-overlooked condition that may begin in childhood – is set to help researchers uncover why millions of women and girls worldwide suffer from infections that defy treatment and stump microbiologists.
A study has revealed a genetic shortcut that may help Giardia duodenalis and many other parasites jump to new hosts at the cost of long-term survival. The findings may also help explain how parasites evolve drug resistance.
Researchers have found unusually high levels of parasitic infection in the insects that transmit Chagas disease in the Borderlands. The bugs were collected near homes and natural areas along the U.S.-Mexico border.
New industry-led good practice guidance for manufacturers and retailers of certain ready to eat (RTE) foods will be published on 12 January 2026 to help Food Business Operators (FBOs), Competent Authorities (CAs) and enforcement officers manage the risk posed by Listeria monocytogenes in those products.
A groundbreaking new study reveals that changes to the gut microbiome can change the way the brain works. It provides the first empirical data showing the direct role the gut microbiome plays in shaping differences in the way the brain functions across different primate species.
Infectious disease researchers have identified Pteropine orthoreovirus (PRV), an emerging bat-borne orthoreovirus, in archived throat swab samples and virus cultures from five patients in Bangladesh who were initially suspected to have Nipah virus infection but tested negative.
A study shows that pharmaceutical pollution alters nitrogen cycling and greenhouse gas emissions in coastal sediments. Even environmentally relevant antibiotic concentrations increased N₂O release, suggesting that widespread contamination may enhance estuarine climate forcing.
People newly diagnosed with the most common IBD subtypes, Crohn’s disease and ulcerative colitis, lose beneficial anaerobic bacteria that help with digestion of complex carbohydrates. Patients instead experience a rise in oxygen-tolerant bacteria from the mouth that travel in the gut.