Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
Decades of Ebola preparedness have produced vaccines, diagnostics and treatments, but many were built primarily around Zaire ebolavirus. A new perspective argues that future preparedness should span the wider ebolavirus genus, combining broader diagnostics, multivalent vaccines, conserved therapeutic targets and continuous genomic surveillance.
Read storyIf you drink coffee regularly, it appears to alter not only your gut bacteria but also the physiology of the gut itself. That is the conclusion of a study from the University of Copenhagen, which may help point the way towards better treatments for constipation.
Researchers have imaged the ends of live rod-shaped bacteria at molecular resolution for the first time. The technique revealed structural differences between species and changes linked to cell division, offering a new way to study bacterial surfaces and potentially uncover weaknesses in drug-resistant pathogens.
Researchers have created a hybrid malaria parasite that combines the manufacturing advantages of the strain used in every current whole-parasite malaria vaccine with the much higher liver infectivity of a parasite collected recently in East Africa.
A bacterial metabolic gene may help Plesiomonas shigelloides become more damaging during fish infections. Increasing lipa expression strengthened bacterial attachment and biofilm formation, worsened disease symptoms in catfish and triggered substantial changes in the host immune response.
Wastewater may reveal much more about a community than which viruses are circulating. Researchers found that gut-associated bacterial patterns in sewage were linked with rates of chronic disease, health behaviours and socioeconomic conditions across several Ohio communities.
Ammonia is everywhere in modern life—released by farms, industry, and waste systems—and it reaches people through more routes than most realize. A review maps ammonia’s routes into the body, the liver-gut axis that keeps it in check, and engineered-bacteria transplants emerging as a possible therapy.
Fat tissue grows in two ways: existing fat cells swell, or progenitor cells spawn new fat cells. When new-cell formation falls behind long-term energy surplus, lipids pile up inside aging fat cells. A review argues that Wnt signaling sits at the junction where gut microbial metabolites may decide which way fat tissue goes.
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) is awarding US$853k to UNSW Sydney to support the development of synthetic darobactin analogues, a new class of antibiotic designed to kill multidrug-resistant Gram-negative bacteria.
Dencichine, the hemostatic active ingredient of the herb panax notoginseng is hard to obtain, with earlier engineered E coli strains low-yielding and growing poorly. Researchers have traced the growth defect to a hidden toxicity and their fix resulted in a final strain that produced the highest reported titer to date.
Professor Stephen Obaro, Professor of Pediatrics and Senior Scientist at the University of Alabama at Birmingham, USA , has been named as the winner of the Christiana Figueres Policy to Practice Award.
Antimicrobial resistance is not just biological — it is shaped by conflict, systems, and shared microbial worlds. That’s the idea that will be explored in the latest FREE webinar from the fascinating Microbes and Social Equity 2026 Speaker Series, entitled ’Microbial Worlds in Crisis Inequality and the Politics of Resistance’.
Researchers have discovered that wildlife imports highly influence the possibility of zoonotic emerging infectious disease (EID). This marks the first global measurement of how wildlife trade is linked to outbreaks of animal-borne diseases, across countries and over time.
Not all biodegradable plastics behave the same once they reach landfill-like environments. Researchers found that PHB broke down almost completely within weeks and PLA degraded substantially over several months, while PBAT barely mineralised, revealing how strongly biodegradation depends on environmental conditions and microbial activity.
Researchers have identified a single amino acid difference between rodent- and human-derived Andes virus isolates that changes how a key viral protein behaves inside human cells. The findings help explain biological differences between closely related virus isolates.
Research has helped inform the development of BloomCalma™, a new intimate care product designed to support skin comfort during pregnancy and after childbirth. The product is the latest example of how academic research can be translated into commercial products.
A common genetic variant can weaken the lungs’ defences against bacteria and increase the risk of pneumonia, reveals a new study. The researchers have also discovered a previously unknown mechanism by which the immune system in the airways detects and combats bacteria.
A multidisciplinary team identifies Ruminococcus lactaris as a key tumor-promoting gut bacterium that produces UDP-GlcNAc to hijack the host O-GlcNAcylation system, driving breast cancer progression via an OGT–NFIB–KIT positive-feedback loop.
A new biomimetic nanoparticle treatment for periodontitis is designed to tackle infection, inflammation and tissue damage at the same time. In laboratory and rat studies, the system killed key periodontal bacteria, shifted immune responses towards repair and reduced bone loss.
For nine months, the placenta is the primary support system of the fetus, providing both nourishment and protection. Within hours of birth, it is usually discarded as medical waste. But this organ carries clues for the child’s future health and additional pregnancies for the mother.
Held in North America for the first time, the Pasteur Network Annual Meeting highlighted how artificial intelligence and emerging technologies can advance global health preparedness and response.
Resistance to antifungal medicines in the pathogenic fungus Aspergillus fumigatus is proving more persistent than previously thought. Research shows that fungicides used in agriculture, even those with a different mode of action from these medicines, can help maintain this resistance. This is because different resistance genes ‘hitchhike’ together.
The Ministry of Health is strengthening vaccination and surveillance activities to protect children following the detection of poliovirus type 1 (VDPV1) in two children aged between 6 and 13 months who developed paralysis in Deir Ezzor Governorate.