One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Research uncovers how bacteria fight viruses, opening the door to better virus-based antibiotics
New research has revealed that bacteria detect viruses when a viral enzyme cuts an important sensor molecule in the bacterium, kicking off the immune response. The discovery paves the way for development of better phage therapies that can evade the bacterial immune system.
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NewsSugar amplifies damage done to gut health by antibiotics
Eating sweets while taking antibiotics may worsen the harm done by the drugs to the normal community of bacteria in the gut, a new study has found. The study of hospitalized cancer patients found an additional 21% reduction in the variety of helpful bacterial species present for every 100 grams of sugar consumed in the 48 hours before treatment.
FeaturesTracking the invisible: monitoring microbial processes in freshwater ecosystems using fluorescence sensing
Rivers are dynamic ecosystems driven by microbial processes that regulate carbon and nutrient cycling, organic matter decomposition, and oxygen consumption. Despite their central role in river health, microbial processes remain mostly invisible in routine water quality monitoring programmes, which continue to focus primarily on physicochemical parameters.
NewsWeather and poultry litter shape E. coli survival in onion fields
How long can E.coli survive in the soil beneath an onion crop? A two-year field study suggests the answer depends not only on the type of poultry-based fertiliser used, but also on weather conditions such as humidity, rain, temperature and wind. The findings could help growers and regulators better assess food safety risks as extreme weather becomes more common.
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News
Wealth and health aren’t the only indicators of national happiness – there are also cats. And their parasites!
National happiness is influenced by complex relationships beyond basic economic factors, according to a study that finds that cats and their parasites are strongly correlated with both positive and negative happiness scores worldwide.
NewsFrom silent killer to cellular fuel: chemist unlocks nature’s carbon monoxide sensors
While carbon monoxide (CO) is widely feared as an odorless, deadly household hazard, nature views it quite differently. In the microscopic world, carbon monoxide serves as an essential cellular messenger and a vital lifeline of energy for microbes thriving in harsh environments.
NewsViral infections can accelerate the progression of ALS, researchers find
A new study suggests that common viral infections — like influenza or COVID-19 — may accelerate the onset and progression of amyotrophic lateral sclerosis, or ALS. The findings suggest that it is the immune response triggered by these infections that accelerates the onset and progression of ALS.
News‘Molecular movie’ fills in blanks of how non-enveloped viruses infect cells
Researchers have answered a longstanding question about how certain non-enveloped viruses punch through the cell membrane to deliver their genetic material. The findings deepen understanding of virology and could aid the biotech industry’s search for ways to deliver relatively large therapeutic agents into cells to treat or prevent disease.
NewsGel and water reveal bacteria’s hidden world
What if the answer to seeing beyond the limits of a microscope was simply to make the bacteria bigger? Scientists have used gel and water to physically expand tiny cells, revealing structures that conventional optics struggle to resolve. The technique gave researchers a clearer view of Chlamydia and new insight into how its DNA is organised.
NewsWater transformed into a weapon against antibiotic-resistant bacteria
Engineers have developed a new approach for turning ordinary water into a weapon against antibiotic-resistant bacteria, according to a study that hinges on a new kind of crystal made from titanium dioxide. These crystals transform the normal oxygen molecules in water into a special molecule known as “singlet” oxygen.
NewsCell by cell: New machine-learning-based method reveals what can make bacteria dangerous
A new method detects fluorescently labelled bacteria inside human cells and uses machine learning to analyse microscopy images. This allows researchers to measure, in the same experimental system, how efficiently bacteria enter cells, how strongly they accumulate inside them, and what kind of DNA damage they induce.
NewsNew treatment aims to achieve lasting cure for persistent bacterial vaginosis
Researchers and clinicians are trialing new combinations of antibiotics to treat persistent bacterial vaginosis (BV), following their landmark discovery that the condition is sexually transmissible. A new study reveals why some women continue to experience a repeat diagnosis of BV even when their male partners are treated concurrently.
VideoSoil Stars Heligan Summit Highlights
Watch highlights from the Soil Stars Heligan Summit and hear from those involved about the ideas, discussions and ambitions that shaped the meeting.
NewsGlobal launch of cosmetic product based on AFYREN’s 100% natural propionic acid
A new cosmetic product formulated with AFYREN ingredient now available for skincare professionals and consumers
NewsCrawling Asgardians: Unexpected dynamics of ancient microbes discovered
Microbiologists placed Asgard archaea in an oxygen-free environment and filmed the living cells under a microscope. This resulted in the first live-cell recordings, which show dynamic changes in shape and a novel crawling movement across surfaces. The results reveal a remarkably dynamic, actin-based cytoskeleton, with parallels to that found in human cells.
NewsPneumonia can reveal undiagnosed blood cancer
Severe pneumococcal disease requiring hospitalization, most commonly pneumonia, can be a sign of previously undiagnosed blood cancer and immunodeficiency in adult patients, according to a study.
NewsResearchers work toward universal flu, HIV vaccines
What if there was a way to achieve stronger, multi-year protection from a single flu jab? Researchers are looking to better understand a viral mechanism shared between influenza and HIV with the aim of disrupting infection. This research could help develop effective vaccines for both diseases, as well as new antivirals.
NewsBlueberries modify gut microbiome in older adults with mild depression
A new pilot study has found that older, sedentary adults who consumed blueberries daily showed a greater, more consistent reduction in depressive symptoms, paired with minor changes in markers of gut microbial enzymes.
NewsResearchers warn eye infections can cause preventable vision loss
Rising rates of infectious eye diseases are increasing the risk of preventable sight loss, with researchers warning that delayed diagnosis can have lasting consequences. New reviews highlight the importance of recognising symptoms such as blurred vision, floaters and sudden visual changes early, when treatment is most effective.
NewsFirm advances measles antibodies toward clinical development
Researchers have identified two potent human monoclonal antibodies that could become the first antibody-based therapy for measles. The antibodies strongly neutralized the virus in laboratory studies and animal models, offering a potential new option for vulnerable people who cannot safely receive or fully benefit from vaccination.
NewsGut enzyme links microbiota, barrier dysfunction and MASH progression
Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis. A new study identifies intestinal neutral ceramidase as a gut-derived driver of MASH progression through its effects on microbial metabolism, epithelial signalling and intestinal barrier function.
NewsAnti-cancer molecules show promise in the fight against malaria
Molecules known for their anti-cancer activity have proven effective in combating Plasmodium falciparum, the parasite that causes malaria. Researchers also investigated how differences in the structure of these molecules affect their impact on the parasites.
NewsHoneybee silk could power smarter wound dressings
Recombinant honeybee silk can be bioengineered in a lab, allowing researchers to modify the protein sequence and potentially introduce new features into the materials, such as infection-sensing signals or targeted drug release.