One health
Communicable diseases remain one of the major causes of mortality worldwide. There are disparities in the numbers of individuals affected by disease between low-and-middle-income countries and those in developed nations. Microbes will play in important role in drug discovery: producing anticancer drugs and antimicrobials. Applying One Health principles, to understand the interaction of pathogens and the human host, development of diagnostics, treatments, and disease prevention, applied microbiologists can shape global health and wellbeing outcomes.
News
Unseen allies: symbiotic bacteria help clean wastewater, but there is a catch
Scientists have identified new species of denitrifying endosymbionts in wastewater, highlighting their global prevalence – with an unexpected climate implication.
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NewsGut bacteria from amphibians and reptiles achieve complete tumor elimination
Researchers have discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity.
NewsHidden viruses in wastewater treatment may shape public health risks, study finds
A new study reveals that viral communities in wastewater treatment plants are far more complex and influential than previously recognized, with implications for water safety, antibiotic resistance, and how treatment performance is monitored.
NewsWho is more likely to get long COVID?
Scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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News
Study uncovers new drug target for huge class of viruses
A study reveals how enteroviruses—including pathogens that cause polio, encephalitis, myocarditis, and the common cold—initiate replication by hijacking host-cell machinery.
NewsA fatal mix-up: How certain gut bacteria drive multiple sclerosis
If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of multiple sclerosis.
NewsOroya fever: Elucidation of disease mechanism opens possibility for novel therapy
An international research team has generated and analyzed more than 1,700 genetic variants of the pathogen that causes Oroya fever, identifying two proteins that Bartonella requires for the destruction of red blood cells.
NewsNew method means contaminated bathing water easier to detect
A new method can provide both faster and more complete answers on whether the water is safe for swimming or not. The innovation has been successfully tested in Helsingborg, where the response time has been reduced from several days to just a few hours.
NewsResearchers see dramatic drop in HIV-infected immune cells in patient after cancer treatment received
Researchers report they may have taken an early step toward a more practical HIV cure. They focused on a patient undergoing cancer treatment and also living with HIV, who after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus.
NewsCOVID-19 vaccination significantly reduces risk to pregnant women and baby
Pregnant women who received a COVID-19 vaccine were far less likely to experience severe illness or deliver their babies prematurely, according to a major new study.
NewsStrategic advancement of second-generation fungal vaccine VXV-01 through Phase 1 trials
The Lundquist Institute (TLI) and its start-up company Vitalex Biosciences (Vitalex) have announced that the second-generation fungal vaccine candidate known as VXV‑01 is poised to move forward in development up to and including Phase 1 clinical evaluation.
NewsA testing paradox for sexually transmitted infections
Surveillance evidence shows an increase in people infected with other STIs after initiating PrEP. A new study provides a counterintuitive explanation revealing a testing paradox: even when the observed cases increase, the true numbers of STIs can decrease.
NewsModulating key interaction prevents virus from entering cells
Researchers have found a way to modulate a common virus protein to prevent viruses from entering cells where it can cause illness. They were able to find and block an important interaction at the molecular level that allows the herpes virus to enter cells.
NewsImmune system keeps mucosal fungi in check
Researchers investigating the mechanisms that keep the fungus under control on our mucosa shed light on how homeostasis is maintained through the fine-tuned interplay between Candida albicans and the epithelial barrier on the one hand, and the immune system on the other hand.
NewsStreptococcus suis serotype 2 collagenase-like protease promotes meningitis by increasing blood-brain barrier permeability
Streptococcus suis serotype 2 (SS2) is an emerging zoonotic pathogen that causes meningitis in humans and pigs. Researchers have investigated the role and mechanism of the SS2 Clp in promoting the passage of the bacterium across the blood-brain barrier (BBB).
NewsHarmless Klebsiella strain shows powerful protection against gut infections in Inflammatory Bowel Disease (IBD) model
A new study demonstrates that a harmless strain of Klebsiella can eliminate infections and reduce gut inflammation in mouse models of inflammatory bowel disease (IBD).
NewsFecal tests reveal active termite attacks
Termite pellets can linger long after the insects that dropped them have disappeared. By testing for microbes in the excrement, researchers can distinguish old droppings from fresh, and whether a colony is actively chewing its way through a home.
NewsStudy links gut bacteria to bloodstream infections in newborns within sub-Saharan Africa for the first time
New research has shown gut and bloodstream infections are caused by the same bacteria giving hope of better prevention and diagnosis of deadly neonatal sepsis.
NewsCould hidden infections be fueling long COVID?
For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but microbiologists think they may have cracked the case. The review argues that co-infections acquired before or during COVID could cause symptoms to persist indefinitely for many people.
NewsEngineering oncolytic bacteria as precision cancer therapeutics
A new review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.
NewsApplications of AI in antimicrobial resistance prevention and control
Researchers have published a review shedding light on how AI is revolutionizing the prevention and control of AMR. The article illustrates how machine learning and deep learning are transforming surveillance, diagnosis, treatment optimization, and drug discovery.
NewsBacteria double as Trojan horse for artificial amino acids
Researchers have hijacked a natural transport system of the bacterium E. coli to develop a solution that allows artificial amino acids to be introduced into bacteria efficiently. This means the “amino acid toolbox” can be expanded for widespread use in medicine and the biotech industry.
NewsPersistent antibiotic resistance of cholera-causing bacteria in Africa revealed
In 2024, representatives from 14 African countries came together for a five-day intensive workshop on a whole-genome sequencing method called Oxford Nanopore Technology (ONT) aimed at strengthening cholera surveillance capabilities across the continent.