All One Health Content
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NewsC. diff uses toxic compound to fuel growth advantage
The pathogen C. diff — the most common cause of health care-associated infectious diarrhea — can use a compound that kills the human gut’s resident microbes to survive and grow, giving it a competitive advantage in the infected gut.
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NewsGrowing body of evidence links HPV with heart disease
In addition to causing several types of cancer, human papillomavirus (HPV) appears to bring a significantly increased risk of heart disease and coronary artery disease, according to a study.
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NewsProbe into human cervical stem cells shows lactic acid bacteria can prevent cervical cancer
Researchers have revealed the identity and differentiation process of human cervical stem cells in a world first study. The results showed that lactic acid bacteria can inhibit the development of cervical cancer.
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NewsResearchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia
Researchers have achieved the biosynthesis of the antiviral ingredient lignan glycoside in yeast Saccharomyces cerevisiae. By mimicking the spatial and temporal regulation of plant biosynthesis, they designed a system with obligated mutualism, enabling metabolic division of labor among different yeast strains.
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NewsSusceptibility to bovine TB in cattle traced to key genes
A new study identifying genetic factors contributing to bovine tuberculosis (bTB) susceptibility has found several key genes and pathways involved in the bovine response to Mycobacterium bovis, the causative agent of the disease in cattle.
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NewsNewer hepatitis B vaccine shows promise as booster for health care workers
A new study compares the effectiveness of Heplisav-B, a new hepatitis vaccine, vs. standard hepatitis B vaccines as a booster in previously vaccinated individuals.
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NewsNew study reveals a safer alternative for long-term hepatitis B treatment
Researchers have studied the effects of switching from long-term tenofovir disoproxil fumarate to the antiviral besifovir dipivoxil maleatein (BSV) in patients with chronic hepatitis B. Switching to BSV may improve patient kidney and bone health.
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NewsRapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing
A study shows that tNGS demonstrates advantages in rapid and accurate UTI diagnosis, particularly in detecting polymicrobial infections and analyzing antibiotic resistance genes. It shows promise as an effective complementary tool for UTI diagnostics.
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NewsBreaking antibiotic-resistant bacteria’s protective shields opens door for immune system response
Researchers have made progress in uncovering how Streptococcus pneumoniae constructs its capsule, which serves as a protective shield. This capsule is a primary target for vaccine development.
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NewsStudy evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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NewsUKHSA highlights pathogens of greatest risk to public health in bid to boost preparedness
The UK Health Security Agency (UKHSA) has today published its view on the pathogen families that could pose the greatest risk to public health, in a bid to focus and guide preparedness efforts against these threats.
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NewsScientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
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NewsNew study sheds light on how bacteria ‘vaccinate’ themselves with genetic material from dormant viruses
Scientists have gained understanding on how bacteria defend themselves from phages, through gaining “memories” from predecessor dormant phages. The study will inform new phage therapies for bacterial infections that confer resistance to antibiotics.
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NewsSimulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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NewsMovie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.
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NewsInfluenza of avian origin confirmed in a sheep in Yorkshire
The UK’s Chief Veterinary Officer has confirmed a case of influenza of avian origin (H5N1) in a single sheep in Yorkshire following repeat positive milk testing.
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NewsBartonella and babesia found in brain tissue of child with seizures
In a new case study, researchers have found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis.
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NewsAntibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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NewsA high-fat diet may impair response to infection
A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system’s ability to respond to infection by impacting the function of neutrophils, one of the first immune cells to respond to bacteria or viruses. The study demonstrated that male mice fed a high-fat ...
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NewsNew model predicts how bacteria navigate obstacles to spread
A scientist has developed the first analytical model for predicting how bacteria spread in environments filled with obstacles. This model will help inform strategies for curbing bacterial infections or for designing better drug delivery.