Emerging evidence is revealing the interplay between AMR and climate change. How are they linked, and how can we address the challenge?
Read storyNovel antimicrobials are desperately needed to combat the AMR crisis, however, the clinical and preclinical pipeline for novel antimicrobials is virtually stagnant. This article will shed light on parasitic worms as an unexplored and underappreciated source of antimicrobial peptides.
Common motifs between Streptomyces and sites of spiritual healing may help with the discovery of new sites for bioprospecting. Although there may be a temptation to dismiss the spiritual nature of the healing sites, it is important that researchers begin to understand these in the appropriate cultural and spiritual context.
The deep expanse of the Earth’s mysterious marine habitat is teeming with opportunities for scientific discovery, including solutions to the world’s most pressing health crises. Among its rich biodiversity are tiny microbes with tremendous potential.
Phages are extremely specific about which strains of a bacterial species they will attack. This has limited their effectiveness against the most antibiotic-resistant strains. To overcome this problem, the research team “trained” the phages by allowing them to evolve together with the bacteria in a controlled laboratory setting for 30 days.
Read storyNew clinical trial results show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
Despite determined efforts by countries and healthcare professionals, Europe is not on track to meet four of the five AMR targets set by the EU Council for 2030*, according to data released on EAAD.
Municipal wastewater contains a large range of excreted antibiotics and has therefore long been suspected to be a spawning ground for antibiotic-resistant bacteria. By testing the potential of untreated municipal wastewater from 47 countries to select for resistant E. coli, researchers show that while some samples indeed do so, most instead suppress them.
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The therapeutic potential of bacteriophages (or ‘phages’) has been widely dismissed for decades in the West, despite being regularly used to treat patients worldwide in the early and mid-20th century. In an age rife with disinformation, can the true potential of clinical phage technology be communicated to a public already uneasy about scientific intervention?
Read storyIn many developing countries, the use of antibiotics in both humans and animals is often indiscriminate and poorly regulated. Could livestock-originated probiotics be a suitable replacement?
The fight against AMR will require innovation, collaboration, and a fundamental shift in perspective – but it’s a fight we can win.
Is it acceptable to prioritize production over welfare?
Megan Stenton reports back on her AMI-sponsored summer studentship which investigated the frequency of the SCCmec gene - a mobile gene element that houses the methicillin resistance gene - across members of the same species of Staphylococcus aureus.
Read storyTaiwo Boluwatife Omowunmi reports back on her AMI-sponsored summer studentship which assessed native microbial strains for mycotoxin biocontrol in stored nuts.
Rachael Barton and Luka Brajdić open up on their experiences of the Letters in Applied Microbiology ECS Symposium 2025 at the University of Liverpool on June 12.
In Neurodiversity Celebration Week, PhD student Joshua Yates reveals the challenges of pursuing a career in microbiology with autism and dyslexia - and his advice to others.