Microfluidics is a fast-growing field focused on manipulating tiny volumes of fluid, often within channels no wider than a human hair. Despite its potential, around 90% of microbial experiments are still carried out under static conditions. So, what are we missing by ignoring flow? And how can microfluidics help close the gap?
Read storyBacteria and their viral predator bacteriophages (phages) have coevolved for billions of years and are engaged in an endless arms race against each other. DNA modifications are among the most widespread defenses to block bacterial RM and CRISPR-Cas systems.
Emerging evidence is revealing the interplay between AMR and climate change. How are they linked, and how can we address the challenge?
Novel antimicrobials are desperately needed to combat the AMR crisis, however, the clinical and preclinical pipeline for novel antimicrobials is virtually stagnant. This article will shed light on parasitic worms as an unexplored and underappreciated source of antimicrobial peptides.
Applied Microbiology International (AMI) has urged global policymakers to strengthen the revised Global Action Plan on Antimicrobial Resistance (GAP-AMR), calling for a more inclusive, clear and equitable approach to tackling one of the world’s most urgent health challenges.
Antimicrobial resistance (AMR) in common foodborne bacteria such as Salmonella and Campylobacter continues to be a public health concern across Europe, according to a new joint report from EFSA and ECDC.
Read storyUsing mice with human antibody genes, scientists have developed new genetically human monoclonal antibodies that prevent two key antigens on the surface of the Epstein Barr virus (EBV) from binding to and entering human immune cells.
New antibody–drug conjugates (ADCs) combine a CD4 mimic with neutralizing antibodies for enhanced suppression of HIV infection. By targeting the gp120 on the viral envelope via a two-step mechanism, the ADCs effectively block viral entry.
Researchers tested antibiotic resistance profiles of a bacterial strain that until recently was hidden in a 5,000-year-old layer of ice of an underground ice cave – and found it could be an opportunity for developing new strategies to prevent the rise of antibiotic resistance.
The therapeutic potential of bacteriophages (or ‘phages’) has been widely dismissed for decades in the West, despite being regularly used to treat patients worldwide in the early and mid-20th century. In an age rife with disinformation, can the true potential of clinical phage technology be communicated to a public already uneasy about scientific intervention?
Read storyIn many developing countries, the use of antibiotics in both humans and animals is often indiscriminate and poorly regulated. Could livestock-originated probiotics be a suitable replacement?
The fight against AMR will require innovation, collaboration, and a fundamental shift in perspective – but it’s a fight we can win.
Is it acceptable to prioritize production over welfare?
Shan Goh from the University of Hertfordshire reports back on the International Symposium on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork held in Rennes, France, in October. Shan was supported with a Scientific Event Travel Grant awarded by AMI.
Read storyDr Kwanrawee Joy Sirikanchana outlines how her team has launched a major project to address an overlooked question: How much does aquaculture contribute to AMR in shared water systems, and what does this mean for people, animals, and wildlife living around them?
Oliver Spiller-Boulter, from Cardiff, reports back on his AMI-sponsored summer studentship which examined antimicrobial resistance (AMR) in neonatal sepsis and the use of novel bacterial screening methods.
Dr Hannah Trivett, University of Birmingham, reports back from EMBL Human Microbiome Conference held in Heidelberg, Germany, where she presented her research with the support of AMI’s Scientific Event Travel Grant.