Among the many naturally occurring antimicrobial compounds, glycerol monolaurate (GML), more commonly known as monolaurin, has attracted renewed interest because of its broad antimicrobial activity and potential role in addressing antimicrobial resistance (AMR).
Read storySince the dawn of time, bacteria have evolved sophisticated ways to wage war against one another. Among the most fascinating of these natural weapons are colicins — protein toxins produced by certain strains of Escherichia coli (E. coli) to eliminate competing bacteria. This article examines how these remarkable molecules were ...
Microfluidics is a fast-growing field focused on manipulating tiny volumes of fluid, often within channels no wider than a human hair. Despite its potential, around 90% of microbial experiments are still carried out under static conditions. So, what are we missing by ignoring flow? And how can microfluidics help close the gap?
Bacteria and their viral predator bacteriophages (phages) have coevolved for billions of years and are engaged in an endless arms race against each other. DNA modifications are among the most widespread defenses to block bacterial RM and CRISPR-Cas systems.
Applied Microbiology International (AMI) has urged global policymakers to strengthen the revised Global Action Plan on Antimicrobial Resistance (GAP-AMR), calling for a more inclusive, clear and equitable approach to tackling one of the world’s most urgent health challenges.
New research has revealed that bacteria detect viruses when a viral enzyme cuts an important sensor molecule in the bacterium, kicking off the immune response. The discovery paves the way for development of better phage therapies that can evade the bacterial immune system.
Read storyEating sweets while taking antibiotics may worsen the harm done by the drugs to the normal community of bacteria in the gut, a new study has found. The study of hospitalized cancer patients found an additional 21% reduction in the variety of helpful bacterial species present for every 100 grams of sugar consumed in the 48 hours before treatment.
Engineers have developed a new approach for turning ordinary water into a weapon against antibiotic-resistant bacteria, according to a study that hinges on a new kind of crystal made from titanium dioxide. These crystals transform the normal oxygen molecules in water into a special molecule known as “singlet” oxygen.
Global health risks continue to emerge where people, animals and the environment meet. A new review highlights that managing these threats requires more than reacting to individual outbreaks: health systems need to monitor the biological, ecological and institutional conditions that allow risks to build.
Animals live in close partnership with communities of microbes that support digestion, immune development, and defence against pathogens, but human activities are changing those partnerships, says Katherine M. Lagerstrom.
Read storyA dream holiday can quickly become a public health challenge when thousands of people share the same dining rooms, elevators and living spaces. Recent viral outbreaks on cruise ships have shown just how vulnerable these floating cities remain to infectious diseases.
Chris Armstrong, President of Microbiology, Thermo Fisher Scientific, argues that laboratories should stop judging fungal culture media on unit price alone.
The therapeutic potential of bacteriophages (or ‘phages’) has been widely dismissed for decades in the West, despite being regularly used to treat patients worldwide in the early and mid-20th century. In an age rife with disinformation, can the true potential of clinical phage technology be communicated to a public already uneasy about scientific intervention?
The Microbiologist gets to know our Global Ambassador for the UK, Professor Sanjib Bhakta who is Professor of Molecular Microbiology and Biochemistry at Birkbeck, University of London.
Read storyPhD student Wewerly Fernandes outlines her investigations into the microorganisms living in Britain’s historic wells and natural springs - once believed to hold healing properties and linked to legends of Merlin and renowned figures like Robert Burns.
Pharmacist and microbiologist Dr Thomas Thompson reveals how AMI membership has played a central role in reaching the point where he is about to start building his own research programme in the School of Pharmacy at Queen’s University Belfast.
Organoid systems are three-dimensional cellular models derived from primary (human or animal) cells that mimic the architecture and function of tissues. These systems provide powerful platforms to investigate host–microbiota interactions under controlled physiological conditions.