All One Health Content – Page 108
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NewsBlindness from some inherited eye diseases may be caused by gut bacteria
Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher. The international study observed that in eyes with sight loss caused by a particular genetic ...
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NewsSpace-grown antiviral drug successfully brought back to earth in private Varda Space capsule
Space-grown crystals of an antiviral drug have been brought to earth following the successful recovery of the capsule from Varda Space Industries’ W-1 mission.
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News‘Dynamic duo’ defences in bacteria ward off viral threats
Scientists have discovered that bacteria can pair up their defence systems to create a formidable force, greater than the sum of its parts, to fight off attack from phage viruses.
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NewsCOVID vaccine during pregnancy improves neonatal outcomes
A study has found that neonates of booster-vaccinated mothers had less risk of being infected with COVID-19 compared to those of unvaccinated mothers. Neonates of unvaccinated mothers died twice as frequently as those of vaccinated mothers.
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NewsMice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study.
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NewsAI provides the most complete map of interactions key to bacterial survival
Researchers have produced the most complete map of the bacterial essential interactome, i.e. how proteins combine and interact to perform functions essential for their survival.
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NewsCopies of antibiotic resistance genes greatly elevated in humans and livestock
Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. The research shows bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance ...
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NewsSK bioscience’s typhoid conjugate vaccine achieves WHO prequalification
SK bioscience and the International Vaccine Institute (IVI) announced that the typhoid conjugate vaccine developed by SK bioscience with technology transfer from IVI has achieved the World Health Organization prequalification (PQ).
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NewsComplement system response to AAV vector gene therapy
Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer – activation of the complement system.
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NewsGut microbes may cause some COVID-19 patients to have higher blood clot risk
A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis – the formation of blood clots – and is accumulated in individuals with COVID-19.
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NewsStudy examines medical mystery of child hepatitis outbreak
A study into an unexpected wave of severe hepatitis cases in 2022 supports the theory that it was caused by an infection of different viruses at the same time, but also reveals cases were higher and more severe than initially thought.
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NewsNew method detects pathogens faster and more accurately by melting DNA
A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, producing results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
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NewsPhage therapy eradicates pan-resistant priority pathogen in vivo, study shows
A new study describes the use of phage therapy to eradicate multi-drug resistant Pseudomonas aeruginosa infections in a living organism (in vivo) with important new implications to antibiotic resistance.
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NewsResearchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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NewsLong-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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NewsScientists win $434k grant to induce microbes to desert their protective biofilm
Researchers are pursuing biofilm dispersal agents such as specific enzymes in hopes the enzymes can induce microbes to leave the safety of the protective biofilm and become more susceptible to antibiotics.
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NewsScientists craft enhanced viral structure in VLP vaccines through polymer restructuring
Researchers reported a viromimetic polymer nanoparticle vaccine (VPNVax), crafted by rearranging the RBD proteins of the coronavirus and modifying them onto the surface of pre-assembled polyethylene glycol-polylactic acid polymer nanoparticles.
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NewsUptake of HIV prevention medication doubles with mix of digital health interventions
A combination of interventions of one-on-one telehealth coaching, peer support forums, and automated text messages more than doubled the use of the HIV prevention strategy, called PrEP, among younger, at-risk Americans.
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NewsStudy finds high number of persistent COVID-19 infections in the general population
A new study has found that a high proportion of SARS-CoV-2 infections in the general population lead to persistent infections lasting a month or more, with some of these showing a high number of mutations.
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NewsBat mating swarms may be the key to solving the next pandemic
The evolution of viral tolerance in Myotis bats may help scientists prevent future pandemics, say researchers.