All One Health Content – Page 11
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Professor Sabiha Essack wins Christiana Figueres Policy to Practice Award
Professor Sabiha Essack, the South African Research Chair in Antibiotic Resistance and One Health, Professor in Pharmaceutical Sciences at the University of KwaZulu-Natal, has been awarded the Christiana Figueres Policy to Practice Award.
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Bacteria invade brain after implanting medical devices
Researchers have discovered that bacteria can invade the brain after a medical device is implanted, contributing to inflammation and reducing the device’s long-term effectiveness.
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Scientists discover protein key to bacteria’s survival in extreme environments
A new discovery sheds light on how certain bacteria – including strains that cause food poisoning and anthrax – form spores for survival.
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Immature platelet fraction offers clinical predictor for enhanced platelet recovery in patients with dengue fever
Immature platelet fraction (IPF) is recognized as a marker for thrombopoiesis, but a new study indicates that IPF% can be utilized as a predictor of platelet increase in patients with dengue infection.
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Tunnel-building virus: How Zika transmits from mother to fetus
For the first time, researchers demonstrated the component involved in the tunneling nanotubes built by Zika virus to infect placental cells, an infection mechanism which is unique to the Zika virus alone.
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Newly identified bacterial protein helps design cancer drug delivery system
Researchers have identified a previously unknown bacterial protein, the unique structure of which acts as an actin homolog that can be used to design protein nanoparticles for the targeted delivery of anticancer drugs to tumors.
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Magnetic microalgae on a mission to become robots
A team of researchers has developed a green algae-based biohybrid micro swimmer covered with magnetic material, whose swimming ability is largely unaffected by the coating.
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Research uncovers new strategy to reduce tissue damage from flesh-eating bacteria
A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as necrotizing fasciitis.
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Add some spice: Curcumin helps treat Mycobacterium abscessus
Researchers have found that adding curcumin boosts the efficacy of bedaquiline, an antimycobacterial used to treat tuberculosis, in combating M. abscessus infections. Curcumin is the compound that gives turmeric its characteristic bright orange color.
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Helicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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Current antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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Metagenomic analysis of tick-borne viruses in Inner Mongolia
A new study maps the landscape of TBVs in Inner Mongolia, but also highlights the potential spillover risk of TBVs. These findings underscore the urgent need for One Health strategies for monitoring emerging TBVs at the tick-human-livestock interface in northern China.
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NIH-sponsored trial of Lassa vaccine opens
A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.
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From order to chaos: Understanding the principles behind collective motion in bacteria
A new study has revealed how bacterial swarms transition from organized movement to chaotic flow. Combining large-scale experiments, computer modeling, and mathematical analysis, the team uncovered intermediate states that emerge between order and turbulence.
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Epstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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COVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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Genetic resistance factors and antimicrobial resistance phenotypes in methicillin-resistant Staphylococcus aureus isolates of animals and humans
A new study identified three functional protein families in MRSA, through sequencing, that confer extensive antibiotic resistance independent of the known antibiotic resistance determinants, mecA and mecC.
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New CRISPR-based diagnostic test detects multidrug-resistant pathogens in blood without amplification
A highly sensitive amplification-free CRISPR-based diagnostic test is developed to rapidly detect pathogens, including multidrug-resistant bacteria, at low concentrations in blood samples.
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Study finds new targets needed for vaccine to prevent herpesvirus transmission to babies
Despite the lack of research on vaccines against congenital cytomegalovirus (CMV), a research has recently discovered that the virus is able to cause cross-placental transmission even with the absence of multple essential proteins, providing insights for future vaccine development.
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CeSPIACE: A broad-spectrum peptide inhibitor against variable SARS-CoV-2 spikes
CeSPIACE, a small remodified peptide, is able to block the binding of ACE2 receptor and the spike protein on SARS-CoV-2 and its variants. Hence, the cheap and simple peptide could treat COVID-19 infection and prevent reinfection after exposure of the virus.