All One Health Content – Page 13
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Presence of potentially toxic microalgae confirmed in La Concha Bay
The proliferation of the Ostreopsis ovata algae is no cause for alarm, but it is advisable to continue taking measurements, according to researchers.
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New study highlights gaps in HPV-related cancer prevention for people living with HIV
A new study reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities. It highlights existing disparities in healthcare for this vulnerable population.
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New immune mechanism revealed in the cellular trash
The enzyme, proteasomes known for its protein degradation and recycling system, has found to serve another useful purpose that provides promising alternatives for strengthening immune defenses against deadly diseases.
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Clove oil yields new Pickering emulsion formulation with enhanced antibacterial properties
Researchers developed a sustainable Pickering emulsion using carbon quantum dots (CQDs), promising solid particles for food applications, derived from clove essential oil residue. They found that CQDs with 40% ethanol demonstrated the highest emulsifying efficacy.
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Multi-dose vaccines administered in the same site boost immune response
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
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Gut bacterium IDed as key player in healing the colon
Researchers have identified Clostridium scindens, a bacterium that converts primary bile acids into 7α-dehydroxylated bile acids, as a key player in gut healing. Supplementing the gut with this bacterium could improve recovery from colonic injury.
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Intranasal herpes infection may produce neurobehavioral symptoms, study finds
A new study finds that herpes infection through the nose can lead to anxiety, motor impairment and cognitive issues. The research is the first to show that, by exploiting a cellular enzyme, the virus can produce behavioral symptoms.
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Study discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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Microbiome: Researchers improve bacterial analysis for clinical applications
Different extraction methods can obtain the DNA of certain bacterial species differently, which can significantly distort the determined microbiome composition. Scientists have developed a computer-based method for correcting extraction bias.
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Prevalence of neutralizing antibodies to AAV2 and AAV9 in individuals with Niemann-Pick disease
A new study shows that more than half of individuals with Niemann-Pick disease, type C1 (NPC1) who were tested lacked neutralizing antibodies against either adeno-associated virus (AAV) 2 or AAV9.
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Genes combined with immune response to Epstein-Barr virus increase MS risk
In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.
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New discovery and grant to accelerate Strep A vaccine efforts
With a large sum of research funding and multinational contributions, the world’s only Strep A human challenge model will be used to resolve logistical issues and speed up the development of a successful Strep A vaccine.
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Novel enzyme found in gut bacteria could revolutionize prebiotic research
Researchers have discovered a new β-galactosidase enzyme in a human gut bacterium that breaks down and synthesizes previously unexplored glycans, which have prebiotic capabilities to improve gut health.
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Dermatophytes adaptation to the human host exemplified by Microsporum canis
Through comparative genomic analyses, researchers investigated the evolutionary mechanisms that underpin gene expansions to enable dermatophytes, such as Microsporum canis to transition from animal to human hosts.
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Early-life gut microbes may protect against diabetes, research in mice suggests
A research discovered that the colonization of a fungus called <i>Candida dubliniensis</i> in the early life gut microbiome of mice, is able to promote growth of pancreatic beta cells in the presence of macrophages to restore blood insulin level and improve metabolic functions, thus reducing risks of type 1 diabetes.
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Purified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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Scientists develop low-cost handheld sensor test for airborne bird flu
Researchers have developed a prototype sensor that detects a virus that causes bird flu (H5N1) in air samples. The low-cost handheld sensor detects the virus at levels below an infectious dose and could lead to rapid aerosol testing for airborne avian influenza.
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Antimicrobial resistance in soil bacteria without the use of antibiotics
Overuse of antibiotics is currently the primary reason for the rise of antimicrobial resistance (AMR), but researchers have shown that AMR can be found in soil bacterial communities due to microbial interactions too, driven by a species of predatory bacteria.
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siRNA-AGO2 complex inhibits bacterial gene translation: a novel therapeutic strategy for superbug infection
Scientists have demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of the mRNA that shares sequence complementarity to the siRNA.
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Effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in amyotrophic lateral sclerosis
Studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. A prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in ALS patients.