All One Health Content – Page 18
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Groundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials. The mRNA vaccine was successful in triggering an immune defence response that helped to reduce TB numbers in infected mice.
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Scientists warn of increased mpox transmission
International researchers warn that the ongoing mpox outbreak in the Democratic Republic of the Congo (DRC) has the potential to spread across borders more rapidly. The mpox virus has mutated, and the new variant, clade 1b, has become more infectious.
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Scientists uncover how bacterial resistance to synergistic drug treatments is arising
Scientists investigating the potential of combined and more powerful drug treatments have found that antimicrobial resistance to these is arising via the vitamin B2 synthesis pathway.
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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New therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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Feed additives can reduce campylobacter in free-range broilers
Trials have demonstrated that adding biochar to chicken feed can significantly reduce campylobacter in chickens, which could potentially lead to fewer campylobacter-associated foodborne diseases in humans.
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Neonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens the door to new treatments.
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Expedition confirms spread of highly pathogenic avian influenza virus in the Weddell Sea
The CSIC-UNESPA scientific expedition monitoring the presence of the highly pathogenic avian influenza virus (HPAI H5N1) in Antarctica has confirmed the presence of the virus in all species detected on six islands in the Weddell Sea.
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Novel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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1 in 5 older adults get infections after heart surgery, and women have a 60% higher risk
One in five older adults gets an infection up to six months after heart surgery, with women far more likely to develop one, according to two studies which examined thousands of cases of coronary artery bypass grafting.
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Researchers ID key immune differences that make one West African ethnic group less susceptible to malaria
Researchers have uncovered how genetic and lifestyle factors influence immune responses to malaria in children from two large West African ethnic groups. Children showed key differences in immune cell activity offering greater protection.
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Transforming HIV diagnosis: a low-cost, point-of-care detection solution
A team of researchers has developed an innovative handheld device for human immunodeficiency virus (HIV) detection that combines paper-based sample preparation with real-time isothermal amplification.
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Rapid diagnostic tests improve diagnosis access to indigenous Paraguayan community for Chagas disease
A study has shown that combining rapid diagnostic tests (RDTs) with conventional serological tests proves to be a useful strategy for diagnosing Chagas disease in an indigenous community in the Paraguayan Chaco with its higher prevalence of the disease.
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AMI member Christopher Stewart named as finalist in 2025 UK Blavatnik Awards for Young Scientists
Applied Microbiology International member Dr Christopher Stewart of Newcastle University has been named as a finalist for the eighth Blavatnik Awards for Young Scientists in the UK. He is the 2023 winner of AMI’s WH Pierce Prize for microbiology.
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Fungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
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Mass polio vaccination campaign to continue in the Gaza Strip
The emergency polio outbreak response in the Gaza Strip is continuing, with a mass vaccination campaign scheduled from 22 to 26 February 2025. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age.
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Ground-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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Plague transmission may have begun a century before the Black Death, study shows
Evidence from 13th-century chroniclers and physicians indicates plague may have been involved in epidemics a century before the Black Death, a new study shows. Source: Dschingis Khan und seine Erben (exhibition catalogue), München 2005, p. 253 Conquest of Baghdad by the Mongols 1258. Right part of a double-page ...
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Ultrasound cleaning promotes phenolic synthesis in fresh-cut red cabbages
Not only can ultrasonic cleaning technology enhance the quality of fruits and vegetables and reduce microbial contamination on their surfaces but it can also serve as an abiotic stressor, inducing the synthesis and accumulation of bioactive compounds.