All One Health Content – Page 19
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News
Scientists unveil novel anti-CRISPR protein mechanism
Apart from their counter-defensive function, anti-CRISPR proteins hold great promise for enabling more precise control over CRISPR technologies. Researchers have now further elucidated the function of an important yet so far uncharacterized anti-CRISPR protein.
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No more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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Researchers uncover how Staphylococcus aureus ‘steals’ iron from our blood during infections
Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin – a process crucial to their survival during infections. The study has identified the full sequence of protein–protein interactions during this iron ‘theft’.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Monitoring approach could help snuff out Legionella outbreaks
Routine, relatively low-cost monitoring of several factors influencing water safety could ward off Legionnaires’ disease outbreaks in hospitals, nursing homes and other health care settings, a new study suggests.
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Using population-level characteristics for the surveillance of antimicrobial-resistant gonorrhea
As the antimicrobial-resistant (AMR) gonorrhea poses a major threat to public health, there is an urgent need for expanding the surveillance of its prevalance to control the spread of the pathogen, through monitoring its association with the population density and HIV prevalence in cities.
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The hidden battle in your gut: How one bacterium outsmarts its rivals
Scientists have undertaken a deep dive into the inner workings of the ‘microbial arms race’ in your gut, revealing an elegant strategy that gut microbes use to stay a step ahead of their neighbors.
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Eliminating HIV funding program would lead to >600k deaths in South Africa alone: warning
A new analysis finds that eliminating PEPFAR would lead to 601,000 HIV-related deaths, 565,000 new HIV infections, and would increase population-level healthcare expenditure by $1.7 billion over the next decade in South Africa alone.
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Long Reads
Advancing microbial research in the North East Indian Himalaya: a pathway to sustainable hill agriculture
While the North East (NE) Indian Himalaya are famous for their stunning landscapes and rich biodiversity, the region faces numerous agricultural challenges that threaten environmental sustainability and food safety.
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Open water swimmer contracts Legionnaires’ disease from lake dip
Swimming in some lakes with still water can lead to infection with Legionella, bacteria that can cause pneumonia, and people who engage in open water swimming should be aware of this risk, a new paper warns.
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Ventilation fans can significantly lower the risk of inhaling bacteria particles after toilet flushing
New research finds that unhealthy concentrations of bacteria are released into the air by toilet flushing - but active ventilation with an exhaust fan reduce the risk by 10 times.
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Stalled microbiomes: cystic fibrosis disrupts early gut development in infants
A new study highlights key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that of healthy infants, and how these alterations may adversely affect their health.
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Evolutionary tradeoffs: Research explores the role of iron levels in COVID-19 infections
Iron has been found to be essential to both human physiology and pathogen replication. The richer the iron availability, the more likely to be susceptible to infections, such as COVID-19. A balance of iron levels is thus critical for homeostasis and preventing pathogenic infections.
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Killing H5N1 in waste milk — an alternative to pasteurization
Researchers have found that acidification can kill H5N1 in waste milk, providing dairy farmers an affordable, easy-to-use alternative to pasteurization of waste milk.
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Researchers explore Spanish flu’s impact on Appalachia
A new book examines how the 1918 influenza pandemic disproportionately impacted Appalachian communities, exacerbating long-standing health disparities. Those included limited health care access, poor working conditions and systemic poverty.
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Researchers create world’s largest digital microbe collection to transform health research
Researchers have created the world’s largest collection of digital microbes - nearly a quarter of a million computer models - to help revolutionise our understanding of the human microbiome and its impact on health.
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Researchers unlock new potential porcine virus treatment
Researchers have identified a novel small molecule for the development of preventative treatment for porcine reproductive and respiratory syndrome virus (PRRSV).
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Researchers review strategies for the modification of vaccinia virus towards a better vaccine vector
A new review delineates the commonly targeted viral genes for attenuation during vaccinia virus (VACV) vector modification and provides an overview of the progress in VACV-vectored vaccine development.
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New method ‘fishes’ for bacterial STI DNA, revealing how Chlamydia spreads and adapts
Scientists have developed a cutting-edge “target enrichment” technology for bacterial STIs. Using specially designed molecular probes, they “fished” for bacterial STI DNA from clinical samples, enabling high-resolution genome analysis.
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New modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.