All One Health Content – Page 29
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NewsCARB-X funds Melio to develop rapid diagnostic to detect neonatal sepsis
CARB-X will award biotechnology company Melio US$3.5M to develop and execute a technical feasibility workplan for its culture-free platform designed to identify blood stream infections including neonatal sepsis.
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NewsHow fungi strengthen their defenses - and how we could break through them
A research team has discovered that the enzyme Mod5 in the fungus Aspergillus fumigatus plays an important role in the modification of fungal tRNA and helps confer temporary antifungal resistance.
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NewsPromising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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NewsRoute of entry for Semliki Forest virus into the brain revealed, yielding brain cancer treatment hope
Researchers have shown that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and binding to a specific cell type before penetrating deeper into the brain, potentially tagging the virus as an agent for treating brain cancer.
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NewsGut bacteria in a chemical tug-of-war with the body
Researchers have identified a clever trick the body uses to keep gut microbial influence on the metabolism in check. In the intestines, the body modifies the microbial bile acids into a new family of derivatives, called BA-MCYs, using an enzyme named VNN1.
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NewsManure management in China cuts river antibiotic pollution but raises groundwater contamination risks
A study of antibiotic pollution patterns in China’s water systems over the past decade found a 59% decrease in antibiotic pollution in rivers, primarily due to reduced direct manure discharge, but antibiotic leaching into groundwater has increased by 15%.
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NewsNew insights offer hope for developing antiviral therapeutics targeting mpox
New research provides novel perspectives on the biological function of G4s in the lifecycle of MPXV and offer potential avenues for developing antiviral therapeutics targeting mpox prevention and treatment.
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NewsScientists explain how a compound from sea sponge exerts its biological effects
Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects. Now researchers have a better idea of how it works.
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NewsSyringe-wielding germs could crack antimicrobial resistance crisis
Friendly germs armed with their own biological syringes and poisons could hold the key to overcoming the antimicrobial resistance crisis, according to a new study.
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NewsWrong place, wrong time: Why Zika virus hijacks a protein needed for brain growth
A new study shows that the Zika virus hijacks a host protein called ANKLE2, which is important for brain development, to assist its own reproduction. Because Zika can cross the placenta, this can have disastrous consequences in pregnancy.
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NewsScientists engineer substrates hostile to bacteria but friendly to cells
Researchers have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells.
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NewsPet dogs often overlooked as spreader of antimicrobial-resistant Salmonella
Household dogs are an overlooked transmission point for zoonotic pathogens such as nontyphoidal Salmonella, which can cause diarrhea, fever and abdominal cramps, with some infections potentially having life-threatening complications.
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NewsDangerous bacterial biofilms have a natural enemy - thanks to stressed plants
Scientists have discovered a chemical that plants produce when they’re stressed prevents biofilm from forming. The breakthrough offers potential advances in healthcare as well as preventing equipment corrosion in industrial settings.
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NewsT cells’ capability to fully prevent acute viral infections opens new avenues for vaccine development
Scientists have discovered that T cells—white blood cells that can destroy harmful pathogens—can completely prevent viral infection, to an extent previously thought only possible due to neutralising antibodies.
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NewsStudy uncovers new pathway controlling levels of body fat and cholesterol
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study.
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News$1.9M NIH grant will allow researchers to explore how copper kills bacteria
A researcher has received a $1.9 million grant from the National Institutes of Health to continue his research into uncovering how copper can be harnessed to kill harmful bacteria and other microorganisms.
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NewsResearchers launch a pioneering project to study the human virome puzzle
The research, which will explore the universe of viruses living in the human body, is fueled by a $20-million grant from the National Institutes of Health.
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NewsResearchers uncover control mechanisms of polysaccharide utilization in gut bacterium
Polysaccharide utilization loci (PULs) complexes enable bacteria to bind, break down, and import specific polysaccharides, contributing to successful gut colonization. A new study explores how PULs are regulated post-transcriptionally to adapt to environmental changes.
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NewsSmall antibody offers broad protection against influenza
Researchers have discovered an antibody-like molecule that can protect mice from various influenza viruses. The findings could pave the way for new treatments and the development of broader influenza vaccines.
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NewsFeeding your good gut bacteria through fibre in diet may boost body against infections
Researchers who used computational approaches to analyse the gut microbiome composition of over 12,000 peoplefrom their stool samples found that a person’s microbiome ‘signature’ can predict whether their gut is likely to be colonised by Enterobacteriaceae.