All One Health Content – Page 47
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Chemists pioneer metallodrug-antibiotic combination strategy to combat superbugs
A combination of different types of antibiotics with bismuth-based drugs, such as Pepto-Bismol, disrupts bacterial iron homeostasis, effectively restoring the bactericidal function of multiple antibiotics.
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Study reveals how our gut cells detect harmful invaders
Researchers hve found that the GPR31 path in ‘gut surveillance’ cells detects bacterial metabolites and triggers immune responses, opening new possibilities for drug development, vaccines, and probiotics to fight infections.
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Floor swabbing could help prevent COVID-19 outbreaks in hospitals
In two Ontario hospitals, high levels of SARS-CoV-2 on floors correlated with COVID-19 cases among healthcare workers and patients, suggesting floor swabbing as a potential method to prevent outbreaks.
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Beyond gut health: prebiotics promise mental wellness
Research shows a prebiotic supplement can reduce inflammation. This could help with symptoms of stress, anxiety, and depression in people with metabolic syndrome.
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Artificial ‘nose’ can sniff out damaged fruit and spoiled meat
The smell of cut grass, or the fumes from refueling your car, are all the result of volatile organic compounds. A new approach to antenna technology can actually detect and identify them.
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MERS coronavirus vaccine tested as safe and effective in phase Ib clinical trial
The safety, immunogenicity and optimal dosing regimen of the MVA-MERS-S vaccine candidate have been investigated in a phase Ib study in healthy individuals who were previously infected with SARS-CoV-2.
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Tuberculosis changes liver metabolism and could promote diabetes
Scientists have discovered that tuberculosis disrupts glucose metabolism in the body and can promote progress to diabetes.
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Major antimicrobial power boost as phages form into surprising flower shapes
Researchers treated bacteria-eating viruses so they could be viewed alive under an electron microscope and coaxed them to join together into flower-like shapes - discovering that this made them 100 times more efficient.
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Study combines woodchips, microbes and biochar to clean water of pharmaceuticals
Researchers show how a simple system using microbially colonised woodchips and a bit of glorified sawdust can dramatically reduce nitrogen, phosphorus, and multiple common drugs in wastewater.
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Study uncovers how Covid-19 is so good at defeating the innate immune response
The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell’s innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses.
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New bacterial toxins discovered: A key to fighting infections
Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments. Found in over 100,000 microbial genomes, they can destroy the cells of bacteria and fungi without harming other organisms.
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Ancient viral DNA in human genome linked to multiple sclerosis and amyotrophic lateral sclerosis
New research has revealed a connection between ancient viral DNA embedded in the human genome and the genetic risk for two major diseases that affect the central nervous system.
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Study reveals insights into oral HPV incidence and risks in men across 3 countries
A new study has unveiled crucial information about the incidence and risk factors of oral human papillomavirus (HPV) infections among men in the United States, Mexico and Brazil - the virus is linked to up to 90% of all oropharyngeal cancer cases in men in the U.S.
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Chemical trick activates antibiotic directly at the pathogen
Scientists have seen promising results after experimenting with a click-to-release approach that deploys a masked form of colistin to the site of an infection so that it is no longer as damaging to the kidneys while maintaining its high antibiotic efficacy.
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Researchers reveal how mucin O-Glycans and food-derived glycoproteins link diet and gut bacteria
A research team investigates how mucin, a major component of the gut lining, and food-derived glycoproteins influence the growth of the bacterium Akkermansia muciniphila, revealing the complex interactions between diet and gut bacteria.
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mRNA vaccine created to prevent and treat C. difficile
The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection.
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Bacteria thrive by playing nice before going their own way
A study tackles the question of how multiple bacterial species coexist in biofilms.
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New microfluidic chip method developed for sepsis prognosis and evaluation
Researchers have developed a new prognostic evaluation method for sepsis patients using a microfluidic concentration gradient chip.
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CDC/PEPFAR awards Georgetown $27.5 million to address HIV/AIDS in Haiti
CDC and PEPFAR have awarded $27.5 million to the Center for Global Health Practice and Impact (CGHPI) at Georgetown University Medical Center to expand its ongoing work in Haiti to address HIV/AIDS.
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Plant fungus provides colorectal cancer drug with a new cellular target
A compound derived from a plant fungus effectively kills colorectal cancer cells by attacking the enzyme DCTPP1, which thus may serve as a potential biomarker for colorectal cancer and a therapeutic target.