All One Health Content – Page 95
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Engineers muffle invading pathogens with a ‘molecular mask’
Researchers are developing a hydrogel therapy that acts as a first line of defense against viruses and other biological threats. The peptides that make up this gel prevent viruses such as SARS-CoV-2 from attaching to and entering cells.
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Optimal timing maximises Paxlovid benefits for treating COVID-19
Study suggests using the anti-COVID-19 treatment Paxlovid three to five days after symptoms emerge in patients and expanding global access to the drug may help reduce the severity and transmission of the SARS-CoV-2 virus.
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Gut microbiota acts like an auxiliary liver
Microbes in the mammalian gut can significantly change their hosts’ amino acid and glucose metabolism, acting almost like an extra liver, according to a new preclinical study.
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The consumption of certain food additive emulsifiers could be associated with the risk of developing type 2 diabetes
Researchers studied the relationships between the dietary intakes of emulsifiers, assessed over a follow-up period of maximum 14 years, and the risk of developing type 2 diabetes in a large study in the general population.
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Promising patient-friendly oral drug against visceral leishmaniasis enters Phase II clinical trial in Ethiopia
The new molecule has the potential to revolutionize treatment for the deeply neglected and hard-to-treat disease, as the Eastern Africa region charts the way to its elimination.
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Undernourished household members at increased risk for developing TB after exposure
Researchers have found that undernourished household contacts are three times more likely to progress to TB disease.
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Odor-causing bacteria in armpits targeted using bacteriophage-derived lysin
Researchers analyzed bacterial metabolism and the DNA of skin microflora in armpit fluid samples and found odor-causing precursors along with a proliferation of Staphylococcus hominis bacteria.
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Researchers use AI to improve Alzheimer’s treatment through the ‘gut-brain axis’
Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer’s disease.
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Pathogens deploy speargun nanomachine to spread unrecognized in the body
Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
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Gut bacteria and inflammatory bowel disease: a new frontier in treatment
A new review highlights the therapeutic potential of various prebiotics derived from different food sources for manipulating gut bacteria.
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$1.8M NIH grant will help researchers follow a virus on its path to the nucleus
Researchers have been awarded a $1.8 million grant to learn how human papillomavirus makes its way to a cell’s nucleus.
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Gut bacteria can change their ‘software’ in reaction to inflammation
New research reveals an ingenious adaptation strategy used by gut microbes, allowing them to dynamically reprogram gene expression based on local conditions like inflammation or viral attacks.
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Safety, immunogenicity and preliminary efficacy of a randomized clinical trial of omicron XBB.1.5-containing bivalent mRNA vaccine
This study reported a very comprehensive evaluation of neutralization against 9 different SARS-CoV-2 variants by three types of variant vaccines of the same delivery system in a head-to-head design.
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Changing relationship between viral replication and the severity of hepatic necroinflammatory damage in patients with chronic hepatitis B virus infection
This study aimed to clarify the relationship between HBV replication and hepatic inflammation during disease progression of chronic hepatitis B virus (HBV) infection.
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Rise seen in use of antibiotics for conditions they can’t treat – including COVID-19
A five-year trend study shows a rebound in inappropriate use after an early-pandemic dip, and a need to tackle overuse in all patients during viral illness outbreaks.
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Impact of COVID-19-related nonpharmaceutical interventions on diarrheal diseases and zoonotic salmonella
The results showed that while the detection rate of most foodborne pathogens declined in China during the pandemic there was an abnormal increase in the detection rate of non-typhoidal Salmonella.
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New technology uncovers mechanism affecting generation of new COVID variants
Researchers have developed a new technology called tARC-seq that revealed a genetic mechanism affecting SARS-CoV-2 divergence and enabled the team to calculate SARS-CoV-2’s mutation rate.
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Gay and bisexual men diagnosed with mpox faced substantial stigma
Gay and bisexual men who were diagnosed with mpox during the 2022 outbreak in England faced substantial issues related to stigma and potentially poor-quality care when accessing services, finds a new study.
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More than half of global infectious diseases experts surveyed rate influenza as the number one pathogen of concern of pandemic potential
When infectious diseases experts were asked to rank pathogens in order of their pandemic potential, influenza was considered the pathogen of highest pandemic risk, with 57% ranking it as number one, and 17% ranking it second.
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DNA vaccine against zika performs well in tests on mice
A Zika vaccine developed in Brazil and tested on mice has been found to be efficacious, inducing an immune response against the virus and protecting the animals appropriately.