All bile acids articles
-
NewsStudy reveals promising gut-targeted therapy for C. difficile infections
Researchers have uncovered how the body’s bile acids bind to block C. diff’s most dangerous toxin. The research has informed the development of a new compound that can protect against C. diff in preclinical models, offering hope for safer, more effective treatments.
-
NewsGroundbreaking review reveals how gut microbiota influences sleep disorders through the brain-gut axis
A comprehensive review illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.
-
NewsGut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study.
-
NewsThe gut microbiota-metabolites-brain axis mediates social behavior dysfunction following anaesthesia
New research shows that the anaesthetic Sevoflurane (Sev) influences social functioning via the gut-brain axis, with microbiota-derived bile acids serving as critical mediators in this pathway.
-
NewsStudy reveals direct gut-brain communication via vagus nerve
A new study in an animal model provides direct evidence for the role of the vagus nerve in gut microbiome-brain communication, addressing a critical gap in the field.
-
NewsGut bacteria in a chemical tug-of-war with the body
Researchers have identified a clever trick the body uses to keep gut microbial influence on the metabolism in check. In the intestines, the body modifies the microbial bile acids into a new family of derivatives, called BA-MCYs, using an enzyme named VNN1.
-
NewsStudy uncovers new pathway controlling levels of body fat and cholesterol
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study.
-
NewsResearchers find previously unknown links between microbial bile acids and the risk of colon cancer
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect our risk — in opposite directions — for developing colon cancer. Source: Photo by ...
-
NewsFinding a preventative solution to a billion-dollar poultry problem
A poultry science researcher is evaluating a new possible solution to losses due to necrotic enteritis, using a novel vaccine combined with a bile acid regimen.
-
News‘Molecular Rosetta Stone’ reveals how our microbiome talks to us
Researchers have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.
-
NewsResearchers team up to publish bile acid breakthrough
Scientists have uncovered a previously unknown way that the microbes living in our gut help to make bile acids.
-
NewsHigh-fat diets alter gut bacteria, boosting colorectal cancer risk in mice
Scientists have pinpointed specific microbes and bile acids that become more prevalent in the guts of mice fed high-fat diets.
-
NewsCocktail of bile salt hydrolases can stop C diff in its tracks
Researchers have found that bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut’s microbial environment.