All Chinese Academy of Sciences articles
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NewsA ‘one-pot’ assay of or rapid portable identification of genotypes I and II African swine fever viruses
Researchers in search of an African swine fever virus genotyping method developed an isothermal ‘one-pot’ CRISPR-Cas12i3/Cas13d-based assay, designated OBServe.v2, to detect two amplified targets from multiplex recombinase polymerase amplification (RPA) in a single tube.
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NewsYeast cell factory developed to convert methanol into L-lactate
Researchers developed a yeast cell factory to produce L-lactate from methanol as the sole carbon source, and evaluated the commercial potential and environmental impacts of this bioprocess.
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NewsA viral fitness-constraint strategy exploits the structural and functional limitations of viral evolution
Researchers have revealed two innovative strategies for the development of durable and broadly neutralizing antibodies against SARS-CoV-2. Their study proposes the immune trajectory strategy and the viral fitness-constraint strategy.
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NewsResearchers boost biosynthetic capacity in yeast through extended lifespan
Scientists have demonstrated that combining lifespan engineering strategies with metabolic pathway optimization in Saccharomyces cerevisiae enables highly efficient sclareol biosynthesis, marking an advance in improving microbial production through lifespan engineering.
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NewsResearchers identify mangrove tree stems as previously underestimated methane source offsetting blue carbon benefits
A new study reveals that mangrove tree stems represent a significant yet previously underestimated source of methane. Additionally, stem emissions showed a strong correlation with soil methane fluxes, indicating that methane produced by anaerobic microbial activity in mangrove soils is transported upward through specialized aerenchyma tissues within the trees.
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NewsNew study reveals microbial network restructuring mitigates long-term soil carbon emissions from warming
Scientists conducted a decade-long study that uncovered a previously unrecognized buffering mechanism in subtropical forest soils mitigating the effects of climate warming.
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NewsGrassland degradation reshapes relationship between biodiversity and ecosystem multifunctionality
Grassland degradation fundamentally reshapes how biodiversity supports ecosystem multifunctionality, shifting it from being plant-dominated to being mediated by soil microbes, according to a new study of alpine grassland on the Tibetan Plateau.
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NewsResearchers reveal novel mechanisms for decoding bacterial frequency modulation in signal processing
A study reveals the fundamental physical principles underlying bacterial FM signal processing, and demonstrated that FM decoding mechanisms enable bacteria to increase information entropy by approximately 2 bits compared to traditional AM in three-gene regulatory systems.
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NewsEngineered membraneless organelles boost bioproduction in Corynebacterium glutamicum
Scientists have successfully engineered liquid-liquid phase separation (LLPS)-driven membraneless organelles (MLOs) within the food-grade industrial strain Corynebacterium glutamicum.
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NewsWhen faucets rest: hidden microbial risks emerge in hours
Stagnant water in building plumbing systems is a well-known driver of microbial growth and contamination, including L. pneumophila. A new study highlights a short “microbial safety window” of 2–4 hours, after which risks increase significantly.
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NewsViruses help cut farm greenhouse gas emissions by targeting soil microbes
A new study reveals that soil viruses can reduce nitrous oxide (N2O) emissions by selectively infecting the microbes responsible for producing this potent greenhouse gas.
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NewsScientists develop rapid and scalable platform for in planta directed evolution
Researchers have developed a new system that enables rapid and scalable directed evolution of diverse genes directly in plant cells. To address the challenge of slow cell division rate in plants, the researchers harnessed geminiviruses.
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NewsScientists reveal functional RNA splitting mechanism behind origin of Type V CRISPR systems
Researchers have uncovered the molecular innovation that led to the origin of Type V CRISPR-Cas immune systems. Their findings show that the functional splitting of transposon-derived RNAs was the critical innovation driving the emergence of Type V CRISPR-Cas immunity.
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NewsNutrient storage and release in uninfected cells of soybean nodules support symbiotic nitrogen fixation in infected cells
A new study employed the symplastic movement tracer carboxyfluorescein diacetate (CFDA) to observe and model the transport and storage status of nutrients within nodules.
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NewsNew study reveals subway station fungal communities
Researchers who collected monthly samples from subway stations in Beijing found high fungal diversity, mostly non-pathogenic. Some opportunistic pathogens were also detected. Fungal communities varied significantly by season and station types.
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NewsResearch breakthrough offers hope for new colorectal cancer treatments
Researchers have identified the key mechanism by which Fusobacterium nucleatum binds to the human cell receptors CEACAM1 and CEACAM5, which are frequently overexpressed on many types of cancer cells.
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NewsAI accelerates design of next-generation antimicrobial peptides with precision targeting
A new opinion article highlights how artificial intelligence (AI), nanotechnology, and interdisciplinary research are revolutionizing AMP design and application, outlining recent breakthroughs in designing, optimizing, and delivering AMPs with enhanced efficacy and safety.
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NewsNew review unveils breakthroughs in soil nitrogen cycle research from microbial pathways to global sustainability
A comprehensive review highlights significant advances in understanding the soil nitrogen cycle, emphasizing the critical role of microbial processes and innovative technologies in achieving global nitrogen sustainability.
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NewsTraditional herb boosts fish health and immunity, study reveals
A groundbreaking study reveals how the traditional herb Picria fel-terrae (PFL) can significantly improve fish health. When added to fish feed at just 0.1% concentration for six weeks, the herb maintained healthy gut structure while reducing inflammation.
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NewsNew study reveals phytoplankton’s contribution to centuries-long ocean carbon storage
Phytoplankton have long been viewed as transient players in the global carbon cycle, but researchers have discovered that these tiny organisms can directly pump “stubborn” carbon into the ocean, where it may persist for centuries.