All colorectal cancer articles
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Study uncovers how low-carb diet drives colorectal cancer development
A new study suggests that a low-carbohydrate diet promotes the growth of a strain of E. coli that produces DNA-damaging colibactin, which drives genetic mutations and predisposes tumour development.
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AMI member Christopher Stewart named as finalist in 2025 UK Blavatnik Awards for Young Scientists
Applied Microbiology International member Dr Christopher Stewart of Newcastle University has been named as a finalist for the eighth Blavatnik Awards for Young Scientists in the UK. He is the 2023 winner of AMI’s WH Pierce Prize for microbiology.
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Long-term yogurt consumption tied to decreased incidence of certain types of colorectal cancer
A new study finds that yogurt consumption over time may protect against colorectal cancer through changes in the gut microbiome. Long-term consumption of two or more servings per week of yogurt was tied to lower rates of proximal colorectal cancer positive for Bifidobacterium.
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Possible colon cancer vaccine target uncovered in bacteria
Higher rates of certain cancers may be linked to two particular strains of bacteria. Targeting these with treatments or vaccines could help reduce the risk of colorectal, bladder, and prostate cancers.
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Common food poison toxin speeds colon cancer spread
A toxin in the bacteria that’s one of the most common causes of foodborne illness accelerates the spread of colorectal tumors to other parts of the body, a study has found.
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Plant fungus provides colorectal cancer drug with a new cellular target
A compound derived from a plant fungus effectively kills colorectal cancer cells by attacking the enzyme DCTPP1, which thus may serve as a potential biomarker for colorectal cancer and a therapeutic target.
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Bacterial vaccine shows promise as cancer immunotherapy
Researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells.
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Chronic stress accelerates colorectal cancer progression by disrupting balance of gut microbiota
Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.
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Circadian disruption and gut microbiome changes linked to colorectal cancer progression
Research has revealed how disruption of the circadian clock, the body’s internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function.
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Fecal DNA testing could reduce global colonoscopy burden: experts
Experts gathered at the ICG 19 · Metagenomics for Health (ICG19·MH) & The 2nd MOHA Consortium have highlighted the global challenge of limited access to colonoscopy, the gold standard for CRC screening.
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Innovations in cancer treatment through targeted bacterial vaccines
Scientists outline efforts to create an antibacterial vaccine capable of eliciting robust immune responses to selectively eradicate Fusobacterium nucleatum while preserving other microbiota.
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New approach to measuring ‘healthy microbiomes’ in nature and the gut
Focusing on four common diseases – diabetes, heart disease, depression and bowel cancer – new research provides insights into the importance of a healthy microbiome balance in the human gut and in the environment.
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Removing gut bacteria’s potential ‘safe house’ may lower risk of colorectal cancer subtype
A new study has found an association between appendix removal and a decreased risk of colorectal cancer positive for tumor-promoting bacteria.
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Scientists reveal interaction mechanism between intestinal microbial environment and tumor immune microenvironment
Scientists have unveiled the mechanism of tumor immune evasion mediated by the microorganism C. scindens in colorectal cancer. Additionally, they developed a phage-based intervention method.
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Microbial signature of colorectal cancer-associated mutations identified in new study
Researchers have identified microbiota signatures associated with KRAS mutations in people diagnosed with colorectal cancer, suggesting that gut microbes may serve as a kind of non-invasive biomarker for identifying subtypes of CRC.
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Bacteria subtype linked to growth in up to 50% of human colorectal cancers
A new study suggests that a subtype of Fusobacterium nucleatum underlies colorectal cancer growth in humans and could be useful in screening and treatments.
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Gut microbiome variations could predict colorectal cancer risk
New research has identified significant variations in the gut microbiome of individuals who developed pre-cancerous colonic lesions, suggesting a potential connection between gut bacteria and the onset of colorectal lesions and cancers.
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Engineered bacteria guide CAR-T cells to poorly infiltrated solid tumors
A new probiotic-guided chimeric antigen receptor (CAR)-T platform uses engineered bacteria to infiltrate and produce synthetic antigen targets, enabling CAR-T cells to find, identify, and destroy tumor cells in situ, according to a new study.
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Nanoparticle may improve mRNA cancer vaccines
Tests in mice with melanoma and colon cancer show the tiny particle creates an ‘army’ of immune cells that carry vaccine’s instructions, say the researchers.
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Gut microbiome changes linked to precancerous colon polyps
A new study has linked certain types of gut bacteria to the development of precancerous colon polyps.