All cryo-electron microscopy articles
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NewsNew research boosts future whooping cough vaccines
By blocking the pertussis toxin epitopes with new found antibodies, researchers improved the pertussis vaccines to provide stronger, long-lasting immunity for infected and high-risk infants.
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NewsMovie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.
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NewsWithout oxygen: How primordial microbes breathed
Scientists decode the fundamental mechanisms of a cell respiratory enzyme in ancient bacterial cells, with potential applications in removing greenhouse gases and drug development against pathogens.
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NewsCeSPIACE: A broad-spectrum peptide inhibitor against variable SARS-CoV-2 spikes
CeSPIACE, a small remodified peptide, is able to block the binding of ACE2 receptor and the spike protein on SARS-CoV-2 and its variants. Hence, the cheap and simple peptide could treat COVID-19 infection and prevent reinfection after exposure of the virus.
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NewsResearchers shed light on the mechanisms of bacterial flagellar motors
Researchers have determined the structure and mechanisms of the key components in the flagellar motor, which bacteria use to turn their flagella and move.
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NewsStructural insights reveal potential drug target in trypanosome parasites
A research group has recently characterised the structural differences between human and trypanosomal nuclear cap-binding complex, a key player in cellular RNA metabolism, for future drug development of trypanosomal diseases.
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NewsScientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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NewsScientists reveal protein synthesis mechanism in Giardia parasite
Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The new insights could be valuable for screening specific drugs against Giardia and other protozoan parasites. Source: CDC/ DPDx - Melanie Moser Trichrome-stained ...
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NewsStunningly detailed blueprint revealed of viral genome replication machinery
Scientists have shed new light on the crucial early stages of RNA virus infection and their control.