All Dirk Tischler articles

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    News

    Scientists unlock indole in soil bacteria to create prodrugs

    2023-03-08T14:47:00Z

    Researchers from Bochum and Leipzig have successfully used a soil bacterium to specifically produce prodrugs. The key to this step was a detailed understanding of the metabolisation of indole, a natural compound which first must be activated in microorganisms. To do this, they needed a monooxygenase, the molecular structure of ...