All Early Life Microbiome articles
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Maldives is first country to achieve ‘triple elimination’ of mother-to-child transmission of HIV, syphilis and hepatitis B
The World Health Organization has validated the Maldives for eliminating mother-to-child transmission of hepatitis B, while maintaining its earlier validation for EMTCT of HIV and syphilis. This makes the Maldives the first country in the world to achieve ‘triple elimination’.
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‘Good’ gut bacteria boost placenta for healthier pregnancy
Research has found the first clear evidence that the ‘good’ gut bacteria Bifidobacterium breve in pregnant mothers regulates the placenta’s production of hormones critical for a healthy pregnancy. Pregnant mice without Bifidobacterium breve in their gut had a higher rate of complications, and increased fetal loss.
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‘Alarming’ rise in newborn babies with antibiotic-resistant infections, researchers find
Researchers are calling for an urgent overhaul of diagnostic and treatment guidelines for infections in newborn babies, after a study revealed frontline treatments for sepsis are no longer effective to treat the majority of bacterial infections.
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RSV vaccines safe and effective, Cochrane review finds
A new Cochrane review demonstrates that vaccines for respiratory syncytial virus (RSV) are both safe and effective in protecting vulnerable groups that are most at risk of serious illness, including older adults and infants.
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Milk matters: How donor human milk storage affects preemie gut health
A study reveals that shorter storage durations of donor human milk are linked to reduced gastrointestinal complicatoins in premature infants, including necrotizing enterocolitis. These findings suggest that minimizing milk storage time may help to preserve protective properties crucial for preterm gut health.
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In pregnant mice with severe flu, harmful molecules can breach fetal barriers
A new study shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain. Fibrinogen can pass into developing fetal brains.
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Special lactic acids reduce antibiotic resistance in infants
Researchers document that a special subgroup of naturally occurring bifidobacteria plays a crucial role in reducing antibiotic resistance in infants.
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Blueberries can improve infants’ immunity and gut health, study finds
Feeding blueberries to infants as one of their first solid foods may help strengthen their immune systems, reduce allergy symptoms and support healthy gut development, according to new research.
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Diet rich in vegetable protein and fiber helps maternal and infant health during pregnancy and breastfeeding
A Mediterranean-style diet, rich in fibre, vegetable proteins and healthy fats, benefits maternal health during pregnancy and breastfeeding. It prevents fat accumulation and optimizes the composition of the microbiota in the digestive system.
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Pediatric investigation study re-examines chikungunya in neglected pediatric victims
Researchers and policymakers must recalibrate their outlook on pediatric chikungunya to develop effective control measures, a new paper warns.
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Even healthy children can be severely affected by RSV
It is not only premature babies and children with underlying diseases who suffer from serious respiratory syncytial virus (RSV) infections. Even healthy, full-term babies are at significant risk of intensive care or prolonged hospitalisation – especially during the first three months of life.
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CARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.
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Maternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.
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Study finds tiny microbes shape brain development
New research finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
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Early challenges to the immune system disrupt oral health
Researchers identified changes over time in the oral microbiome of children living with HIV, offering insights into how early immune challenges shape not only oral health but also systemic health.
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Regional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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Gene therapy may block HIV transmission during breastfeeding, study shows
Delivering broadly neutralizing antibodies against HIV-1 to newborns via gene therapy provided them with multi-year protection from HIV/AIDS infection, according to an animal study.
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New jab protects babies from serious lung infection, study shows
Vaccination of pregnant women has been linked to a drop in newborns being admitted to hospital with a serious lung infection, research suggests.
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Study suggests some maternal HIV infections may be missed during pregnancy
Newborns exposed to HIV during pregnancy or birth should receive antiretroviral medication immediately after delivery - but a study finds more than half of infants diagnosed with HIV in their first year of life had not received this essential postnatal treatment.
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Bacterial genomes hold clues for creating personalized probiotics
A new study demonstrates the ability to predict the nutritional adaptations of Bifidobacterium strains by analyzing the distribution of hundreds of metabolic genes in thousands of Bifidobacterium genomes.