All Early Life Microbiome articles
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NewsCARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.
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NewsMaternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.
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NewsStudy finds tiny microbes shape brain development
New research finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
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NewsEarly challenges to the immune system disrupt oral health
Researchers identified changes over time in the oral microbiome of children living with HIV, offering insights into how early immune challenges shape not only oral health but also systemic health.
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NewsRegional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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NewsGene therapy may block HIV transmission during breastfeeding, study shows
Delivering broadly neutralizing antibodies against HIV-1 to newborns via gene therapy provided them with multi-year protection from HIV/AIDS infection, according to an animal study.
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NewsNew jab protects babies from serious lung infection, study shows
Vaccination of pregnant women has been linked to a drop in newborns being admitted to hospital with a serious lung infection, research suggests.
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NewsStudy suggests some maternal HIV infections may be missed during pregnancy
Newborns exposed to HIV during pregnancy or birth should receive antiretroviral medication immediately after delivery - but a study finds more than half of infants diagnosed with HIV in their first year of life had not received this essential postnatal treatment.
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NewsBacterial genomes hold clues for creating personalized probiotics
A new study demonstrates the ability to predict the nutritional adaptations of Bifidobacterium strains by analyzing the distribution of hundreds of metabolic genes in thousands of Bifidobacterium genomes.
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NewsEarly antibiotics alter immune function in infants- but a gut-derived molecule could help restore it
A new study has found that early-life exposure to antibiotics can impair an infant’s developing immune system, and that a naturally occurring metabolite may hold the key to reversing that damage.
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NewsStudy links influenza A viral infection to microbiome, brain gene expression changes
Infection with influenza A is found to be associated with disruptions in newborn piglets’ nasal and gut microbiomes and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory.
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NewsBaby’s microbiome may protect against childhood viral infection
A baby’s makeup of gut bacteria — their microbiome — which starts to form as soon as they are born, could help protect against viral infections later in childhood, a new study suggests.
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NewsAntibiotics taken during pregnancy may reduce preterm births
A study of almost 1000 pregnant women in Zimbabwe found that a daily dose of a commonly used, safe and inexpensive antibiotic may have led to fewer babies being born early.
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NewsSelenium exposure during pregnancy may reduce childhood streptococcal infections
Higher maternal selenium levels during pregnancy were associated with a lower risk of streptococcal infections in children, a new study shows, suggesting a potential protective effect.
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NewsConsumption of ultra-processed foods by children up to one year old favors harmful bacteria in the gut
Analysis of the gut microbiota of more than 700 babies also showed that breastfeeding was a protective factor, mitigating the problem in those who consumed industrialized products. The study underscores the importance of breastfeeding.
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NewsFrequent use of antibiotics in infants and young children may increase risk for asthma, allergies and other conditions
Researchers have found that repeated antibiotic use before age 2 is associated with a higher risk for asthma, food allergies and hay fever later in life. These findings also applied to siblings who had different experiences with antibiotics.
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NewsDeadly rodent-borne hantavirus is an emerging disease with pandemic potential
Researchers have found three hotspots of hantavirus circulation in wildlife in the US – Virginia, Colorado, and Texas – and identified 15 rodent species as carriers, including six species that had not previously been identified as hosts of the virus.
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NewsHepatitis B: new rapid diagnostic test to halt mother-to-child transmission
Scientists have assessed a new rapid diagnostic test to identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This diagnostic tool could help eliminate hepatitis B by preventing mother-to-child transmission during childbirth.
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NewsAntibiotic exposure in infancy may boost Type 1 diabetes risk - but microbiota can help
Exposure to antibiotics during a key developmental window in infancy can stunt the growth of insulin-producing cells and may boost risk of diabetes later in life. But the research pinpoints specific microbes that may help those critical cells proliferate in early life.
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NewsThe gut microbiota-metabolites-brain axis mediates social behavior dysfunction following anaesthesia
New research shows that the anaesthetic Sevoflurane (Sev) influences social functioning via the gut-brain axis, with microbiota-derived bile acids serving as critical mediators in this pathway.