All Indian Institute of Science articles
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Breaking down bacterial barriers using bovine gut enzyme
A team of scientists has devised a way to break down biofilms which limit the entry of drugs and help bacteria become resistant to antibiotics, using an enzyme from the cow’s digestive tract.
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Novel 3D hydrogel culture to study TB infection and treatment
Researchers have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment, providing a platform to track and study how tuberculosis bacteria infect lung cells and test the efficacy of therapeutics used to treat TB.
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Scientists probe spermidine production to combat emerging drug resistance in Salmonella
Scientists have pinpointed how Salmonella Typhimurium uses a key molecule called spermidine to shield itself from the onslaught of the host’s defence machinery - and an existing FDA-approved drug can reduce spermidine production.
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Researchers track the virus behind India’s lumpy skin cattle crisis
A study provides critical insights into the evolution and origins of the virus strains fueling a devastating outbreak of lumpy skin disease, which has severely affected India’s agricultural sector, leading to staggering economic losses.
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Paper-based platform offers rapid detection of antibiotic-resistant bacteria
A paper-based platform could help quickly detect the presence of antibiotic-resistant, disease-causing bacteria.
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Resaerchers design thermostable vaccine candidate for SARS-CoV-2 variants
Researchers report the design of a synthetic antigen that can be manufactured as a potential COVID-19 vaccine candidate - it is effective against all current strains of SARS-CoV-2 and can be quickly adapted for future variants as well.
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Picolinic acid reveals its broad-spectrum antiviral abilities
Picolinic acid, a natural compound produced by mammalian cells, can block several disease-causing viruses such as SARS-CoV-2 and influenza A viruses, according to a new study.