All influenza A articles
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Study links influenza A viral infection to microbiome, brain gene expression changes
Infection with influenza A is found to be associated with disruptions in newborn piglets’ nasal and gut microbiomes and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory.
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Common drugs can help viruses spread
JAK inhibitors are often prescribed for autoimmune diseases and inflammatory conditions such as rheumatoid arthritis, but scientists have found they also weaken the body’s natural defences against viruses.
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World’s largest bat organoid platform paves the way for pandemic preparedness
Researchers have created the world’s most comprehensive bat organoid platform. These ’mini-organs’ are grown from five common bat species found across Asia and Europe and represent four different organs—airway, lungs, kidneys, and small intestine.
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New vaccine protects against swine, human and bird flu
Annual flu shots could become a thing of the past under a new vaccine strategy. A new study describes a vaccine that protects against H1N1 swine flu and can also protect against influenza in humans and birds.
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Scientists engineer antibody against flu with sticky staying power
Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender. Source: NIAID Colorized transmission ...
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Viruses under the super microscope: How influenza viruses communicate with cells
Scientists have characterized a new model of influenza A infection: binding to MHC class II complexes as an alternative receptor and the associated dynamic reorganization of the cell surface.
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Flu vaccine offers moderate protection against strains dominant in most European countries in 2024/2025
According to interim analysis of influenza vaccine effectiveness for the 2024/2025 season in Europe, the vaccine offered moderate protection against dominant influenza A strains, and strong protection against influenza B.
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Influenza A viruses adapt shape in response to environmental pressures
Influenza A virus particles strategically adapt their shape—to become either spheres or larger filaments—to favor their ability to infect cells depending on environmental conditions, according to a new study.
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From Spanish flu to today: how immune cells keep up with a changing virus
In a breakthrough for influenza research, scientists have discovered immune cells that can recognise influenza (flu) viruses even as they mutate, raising hopes for a longer-lasting vaccine and a universal protection against future flu pandemics.
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Cigarette smoke alters microbiota and aggravates flu severity
New research has shown that cigarette smoke can induce disordered oropharyngeal microbiota that aggravates the severity of influenza A virus infection.
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Child Health Day 2024: influenza vaccine protects children from infection and hospitalization
Spain’s influenza vaccination campaign for children aged 6-59 months during the 2023/24 season was effective in preventing acute respiratory infections and hospitalisation, as vaccination was recommended for this age group at the national level for the first time.
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Could a bout of COVID protect you from a severe case of flu?
More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different one?
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Fruit-only diet improves bats’ immune response to viruses
Fruit bats generate more diverse antibodies than mice, but overall have a weaker antibody response, according to a new study.
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Origami paper sensors could help early detection of infectious diseases in low-cost test
Researchers have developed an innovative new method for identifying biomarkers in wastewater using origami-paper sensors, enabling the tracking of infectious diseases using the camera in a mobile phone.
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High speed atomic force microscopy studies provide insights into influenza A viral replication
Researchers used high-speed atomic force microscopy and electron microscopy to pin down the conformational dynamics of recombinant Influenza A genomes (or rRNPs) during RNA synthesis.
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Mouse study reveals how fetal brain impacted when mother fights severe flu
A bad case of the flu during pregnancy can increase the risk for fetal neurodevelopmental disorders such as schizophrenia and autism spectrum disorder. But it’s not the virus itself doing the damage; it’s the mother’s immune response.
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Wearing a face mask in public spaces cuts risk of common respiratory symptoms, study suggests
Wearing a surgical face mask in public spaces reduces the risk of self-reported respiratory symptoms, finds a trial of adults in Norway.
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Highly pathogenic avian influenza A(H5N1) outbreak in Finnish fur farms
Highly pathogenic avian influenza (HPAI) A(H5N1) has been detected in animals on 27 fur farms in Finland. The outbreak, traced to wild birds, revealed significant virus adaptation to mammals and caused severe inflammation in the lungs, brains and livers.
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Simple test for flu could improve diagnosis and surveillance
A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.
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Community-based cohort study to track short- and long-term effects of multiple respiratory viruses
Scientists are initiating a critical two-year prospective epidemiologic study in the spring of 2024 to track acute respiratory infections across the United States.