Innovation – Page 3
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New vaccine protects against swine, human and bird flu
Annual flu shots could become a thing of the past under a new vaccine strategy. A new study describes a vaccine that protects against H1N1 swine flu and can also protect against influenza in humans and birds.
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Targeted nanoparticles show promise for more effective antifungal treatments
Researchers have developed a new nanotechnology-based approach that could improve treatment of fungal infections, particularly those caused by the increasingly drug-resistant Candida species.
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Activating ‘jumping genes’ speeds up bacterial evolution from decades to weeks
Scientists have developed a system to control and accelerate the evolution of changes in the bacterial genome structure, targeting small ‘jumping genes’, or DNA sequences known as insertion sequences.
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Researchers pioneer novel, needle-free, live-attenuated influenza vaccines with broad protection
Researchers have achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV).
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Self-assembly of a large metal-peptide capsid nanostructure through geometric control
Controlling the topology and structure of entangled molecular strands is a key challenge in molecular engineering. This new hollow dodecahedral shell demonstrates remarkable stability and potential for functionalization and encapsulating macromolecules.
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Predictive AI model can help build vaccines for future versions of a virus
Researchers have created an AI tool called EVE-Vax that can predict and design viral proteins likely to emerge in the future. For SARS-CoV-2, panels of these “designer” proteins triggered similar immune responses as real-life viral proteins that emerged during the pandemic.
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Bacteria: Recording gene activity more efficiently
Researchers have presented a step-by-step protocol for creating single bacterial transcriptomes with MATQ-seq. The protocol also includes the experimental and computer-aided analysis of the data.
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Scientists engineer antibody against flu with sticky staying power
Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender. Source: NIAID Colorized transmission ...
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Synthetic lichen points a pathway to self-healing concrete
Addressing one of the most persistent and expensive problems in construction, scientists have taken inspiration from nature to develop a synthetic lichen system to enable concrete to self-repair.
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Transforming hospital sanitation: autonomous robots for wiping and UV-C disinfection
Scientists have developed an ’Intelligent Autonomous Wiping and UV-C Disinfection Robot’ capable of automating hospital disinfection processes. The system can perform disinfection with consistent precision, significantly reducing the risk of infection within the hospital.
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Foot traffic can predict COVID-19 spread in New York City neighborhoods
A new study reveals how foot traffic data from mobile devices can enhance neighborhood-level COVID-19 forecasts in New York City, providing a novel approach to predicting the spread of the SARS-CoV-2 virus and improving targeted public health interventions.
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Viruses under the super microscope: How influenza viruses communicate with cells
Scientists have characterized a new model of influenza A infection: binding to MHC class II complexes as an alternative receptor and the associated dynamic reorganization of the cell surface.
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High-density screening technique reveals key genes for biotechnology improvements
Scientists used a gene-silencing tool and molecular guides to probe how photosynthetic bacteria adapt to light and temperature changes, finding even partial suppression of certain genes yielded big benefits in modifying the stress response of wild microbes.
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AI plays detective to help scientists find hidden microbes
A team of researchers has created a novel machine learning tool that’s cracking open one of biology’s trickiest puzzles: finding the rarest microbes on Earth. Ulrb not only identifies rare microorganisms but also works with non-microbial data.
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Topical gel relieved ear infections in animals after just one dose
Researchers report a topical antibiotic gel that, applied once, cured middle ear infection within 24 hours in chinchillas. a single dose of treatment for middle ear infections could improve patient compliance and potentially reduce pediatric antibiotic usage.
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Scientists launch intranasal albumin-based vaccine technology platform against respiratory virus
A new paper reports on a novel vaccine technology platform, in which the subunit antigen is genetically fused to albumin. The albumin-antigen fusion vaccines induced both systemic and mucosal antigen-specific antibody responses.
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New molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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A digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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Scientists repurpose gene editing tool to help uncover hidden microbial diversity
Pioneering research has repurposed a gene editing tool to help shed light on the true biodiversity present in natural environments. The study could help pave the way for more productive soils and improved health.
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Controlling starch levels in algae could have biotechnology and sustainability benefits
Researchers have found a new method to control starch storage in algae - a finding with potential applications in areas such reducing greenhouse gases. Modifying a blue light-activated signalling pathway makes it possible to regulate storage, they say.