Innovation – Page 3
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World first clinical trial will study specialized ‘poop pills’ to improve treatment of advanced pancreatic cancer
A world-pioneering fecal microbiota transplantation pill will undergo a clinical trial, aiming to improve immune responses by remodifying the gut microbiome in patients with advance pancreatic cancer.
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New method developed to dramatically enhance bioelectronic sensors
In a breakthrough that could transform bioelectronic sensing, researchers have developed a new method to dramatically enhance the sensitivity of enzymatic and microbial fuel cells using organic electrochemical transistors (OECTs).
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A rapid and reproducible method for generating germ-free Drosophila melanogaster
Scientists have introduced a refined method for the production of germ-free Drosophila, complemented by a straightforward verification process to ascertain its efficacy.
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A*STAR spin-off NalaGenetics implements nationwide drug reaction screening for leprosy patients in Indonesia
NalaGenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), will be transforming leprosy treatments in Indonesia with a nationwide genetic screening programme with their PGx1301 diagnostic kit.
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New paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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Laser-powered device tested on Earth could help us detect microbial fossils on Mars
Scientists hoping to identify fossil evidence of ancient Martian microbial life have now found a way to test their hypothesis, proving they can detect the fossils of microbes in gypsum samples that are a close analogy to sulfate rocks on Mars.
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Scientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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Coffee grounds and Reishi mushroom spores can be 3D printed into a compostable alternative to plastics
Researchers have developed a new system for turning coffee grounds into a paste, which is inoculated with Reishi mushroom spores to form a mycelial skin. The skin turns the coffee grounds into a resilient, fully compostable 3D printable alternative to plastics.
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Transforming HIV diagnosis: a low-cost, point-of-care detection solution
A team of researchers has developed an innovative handheld device for human immunodeficiency virus (HIV) detection that combines paper-based sample preparation with real-time isothermal amplification.
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Ground-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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No more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Monitoring approach could help snuff out Legionella outbreaks
Routine, relatively low-cost monitoring of several factors influencing water safety could ward off Legionnaires’ disease outbreaks in hospitals, nursing homes and other health care settings, a new study suggests.
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Researchers create world’s largest digital microbe collection to transform health research
Researchers have created the world’s largest collection of digital microbes - nearly a quarter of a million computer models - to help revolutionise our understanding of the human microbiome and its impact on health.
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A new system to study phytoplankton: Crucial species for planet Earth
Researchers have come up with a new way to study phytoplankton. They’ve built a system that can measure the light given off by individual phytoplankton cells, which tells them how efficiently each individual is using light.
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Researchers engineer biological reaction crucibles to rapidly produce proteins
Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.
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Scientists recode the genome for programmable synthetic proteins
Synthetic biologists were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins.
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Bacteria, brains, and sugar: scientists uncover new connections
Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain.
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Minecraft players can now explore whole cells and their contents - including yeast and bacteria
Scientists have translated nanoscale experimental and computational data into precise 3D representations of bacteria, yeast and human epithelial, breast and breast cancer cells in the video game Minecraft.