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NewsStructural diversity of pyripyropenes via biosynthetic gene cluster design and heterologous expression in Aspergillus nidulans
Researchers have designed a reconstituted biosynthetic gene cluster (BGC) for producing structurally diversified deacetylated pyripyropenes, using the native pyripyropene A BGC from the wild-type strain Aspergillus fumigatus Af 293 as a template.