All Lassa virus articles
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News
MOPEVACLAS vaccine candidate for Lassa fever enters clinical trials
After more than 20 years of research on arenaviruses, researchers have developed an original vaccine platform known as MOPEVAC. A Phase Ia clinical trial is set to begin for the platform’s first vaccine candidate, which targets Lassa fever, a hemorrhagic fever responsible for thousands of deaths worldwide each year.
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NIH-sponsored trial of Lassa vaccine opens
A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.
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‘Unbreakable’ Lassa vaccine shows promising results
A live-attenuated vaccine candidate against Lassa virus completely protected guinea pigs exposed to an otherwise lethal dose of the virus, researchers have reported.
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Rabies outbreaks in Costa Rica cattle linked to deforestation
Deforestation in Costa Rica raises the risk of cattle becoming infected with rabies by vampire bats, finds a new study.
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Researchers uncover genetic factors for severe Lassa fever
Researchers have found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever.
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Deadly virus structures pinpoint new targets for Lassa vaccine design
By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a research team has identified new antibodies and vaccine targets.