Latest News in WAAW – Page 5
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NewsCentauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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NewsStudy uncovers the core principles of low-resistance antibiotics
Researchers have demonstrated that a dual-target approach, combining membrane disruption with an additional critical cellular pathway, significantly prevents the development of resistance in bacteria.
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NewsResearchers develop enhanced method for wastewater surveillance of antibiotic resistance
To better monitor the emergence and spread of antibiotic resistance, researchers have developed a CRISPR-enriched metagenomics method for the enhanced surveillance of antibiotic resistance genes, ARGs, in wastewater.
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NewsMontana State scientist receives $2.8 million grant to advance Lyme disease research
Funding from the National Institutes of Health will allow a Montana State University research team to deepen explorations into a disease that is posing an increasing threat in the U.S. Lyme disease is a bacterial infection transmitted by ticks.
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NewsReactive nitrogen species dominance is key in the fight against antimicrobial resistance
The balance between two types of molecules – reactive nitrogen species (RNS) and reactive oxygen species (ROS) – plays a crucial role in tackling drug-resistant bacteria, according to a new study.
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NewsNew insights into phage–bacteria interactions in the gut microbiome
Researchers studied the interactions between bacteria and phages within the gut microbiome and highlighted the significance of the phage community to shape the microbiome that contributes to host health and diseases.
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NewsSuperbugs in our food: a new hope for tackling drug resistance
Researchers highlight the potential of quorum sensing inhibitors (QSIs) as a novel approach to tackle Pseudomonas aeruginosa. The study explores the mechanisms of action of various QSIs and potential applications in food safety and healthcare.
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NewsNew paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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NewsScientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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NewsScientists uncover how bacterial resistance to synergistic drug treatments is arising
Scientists investigating the potential of combined and more powerful drug treatments have found that antimicrobial resistance to these is arising via the vitamin B2 synthesis pathway.
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NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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NewsUltrasound cleaning promotes phenolic synthesis in fresh-cut red cabbages
Not only can ultrasonic cleaning technology enhance the quality of fruits and vegetables and reduce microbial contamination on their surfaces but it can also serve as an abiotic stressor, inducing the synthesis and accumulation of bioactive compounds.
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NewsScientists unveil novel anti-CRISPR protein mechanism
Apart from their counter-defensive function, anti-CRISPR proteins hold great promise for enabling more precise control over CRISPR technologies. Researchers have now further elucidated the function of an important yet so far uncharacterized anti-CRISPR protein.
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NewsNo more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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NewsUsing population-level characteristics for the surveillance of antimicrobial-resistant gonorrhea
As the antimicrobial-resistant (AMR) gonorrhea poses a major threat to public health, there is an urgent need for expanding the surveillance of its prevalance to control the spread of the pathogen, through monitoring its association with the population density and HIV prevalence in cities.
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NewsNew modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.
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NewsInternational team publishes guideline on how to manage fungal infections caused by Candida
The new global guideline for the diagnosis and treatment of Candida infections establishes new standards for managing fungal infections, which affect millions of people worldwide every year.
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NewsDangerous bacteria lurk in hospital sink drains, despite rigorous cleaning
Even in modern hospitals, drains can serve as reservoirs for known and novel pathogens, according to a new study.
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NewsProtein shuttling mechanism helps bacteria pump out antibiotics
By a joint-university effort, the mechanism of a bacterial efflux pump complex to remove molecules, including antibiotics, has been determined and the extent of bacterial toxin resistance by the complex has also been evaluated with a cutting-edge device.
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NewsDiabetes can drive the evolution of antibiotic resistance, study reveals
A new study shows that people with diabetes are more likely to develop antibiotic-resistant strains of Staph. The results show how the diabetic microbial environment produces resistant mutations, while hinting at ways antibiotic resistance can be combatted in this patient population.