All Plasmodium falciparum articles
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NewsScientists explain how a compound from sea sponge exerts its biological effects
Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects. Now researchers have a better idea of how it works.
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NewsNew discovery provides hope in fighting drug-resistant malaria
Researchers have described how they may have found a new target in Plasmodium falciparum, the deadliest malaria parasite: a cholesterol-managing protein called PfNCR1.
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NewsGlobal research uncovers critical weakness in malaria parasite
Scientists exploring how immunity develops against Plasmodium falciparum found that broadly reactive antibodies from various individuals consistently bound to the same site on a key virulence protein of the malaria parasite.
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NewsA new approach to predicting malaria drug resistance
Researchers analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.
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NewsNew tool reveals how malaria sticks to red blood vessels
Scientists have unveiled a new tool for studying the highly variable traits that allow malaria parasites to stick to red blood cells and evade the immune system.
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NewsHuman antibodies could prevent the malaria parasite from causing life-threatening infections
Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five. In a new study, published in the journal Nature, researchers from EMBL Barcelona, the University of Texas, the ...
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NewsStudy provides first evidence of African children with severe malaria experiencing partial resistance to world’s most powerful malaria drug
A new study from Uganda provides the first evidence to date that resistance to a lifesaving malaria drug may be emerging in the group of patients that accounts for most of the world’s malaria deaths: young African children suffering from serious infections.
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NewsNoninvasive malaria test could be global game changer
Researchers present a new noninvasive test that could dramatically alter the global malaria testing landscape by providing reliable, safe, and sensitive testing to low- and middle-income countries.
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NewsScientists design new drug to fight malaria
Scientists have designed a new drug against malaria and identified its mechanism of action. MED6-189 is effective against drug-sensitive and drug-resistant P. falciparum strains in vitro as well as in a humanized mouse model.
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NewsFirst-of-its-kind vaccine expands malaria protection for pregnant women
For the first time, immunization with a malaria vaccine has been shown to protect mothers from malaria during pregnancy and to protect for two transmission seasons without booster doses of vaccine.
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NewsNew agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
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NewsUrgent action needed to combat rising antimalarial resistance in Africa
Urgent action is needed to prevent a surge in malaria-related sickness and death in eastern Africa, scientists say.
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NewsLow birth weight linked to placental malaria in first-time mothers
A new study aimed to determine the prevalence of placental malaria infection, risk factors, types of Plasmodium causing malaria during pregnancy, and its relationship with neonatal birth weight among primigravidae.
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NewsGenome research reveals the global march of malaria
Researchers have reconstructed ancient Plasmodium genome-wide data from 36 malaria-infected individuals spanning 5,500 years of human history on five continents, reconstructing the worldwide spread of malaria and its historical impact.
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NewsBreakthrough research identifies mechanism behind drug resistance in malaria parasite
A new study has found that a cellular process called transfer Ribonucleic acid (tRNA) modification influences the malaria parasite’s ability to develop resistance to Artemisinin-based combination therapies.
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NewsDeeper understanding of malaria parasite sexual development unlocks opportunities to block disease spread
For the first time, the developmental stages of the deadliest human malaria parasite have been mapped in high resolution, allowing researchers to understand this ever-adapting adversary in more detail than previously possible.
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NewsMalaria may shorten leukocyte telomeres among sub-Saharan Africans
Researchers have uncovered a potential role of malaria in shortening length of telomeres in white blood cells, known as leukocytes, across sub-Saharan Africa.
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NewsExperimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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NewsClimate change linked surge in malaria transmission could be less than feared
Despite concerns about the potential impact of climate change on increasing malaria risk, there is still limited understanding of how temperature affects malaria transmission – until now.
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NewsStudy reveals impact of malaria interventions through routine sampling of pregnant women
Genomic analysis of the malaria parasite in pregnant women attending their first antenatal visit revealed reduced diversity in areas of southern Mozambique where elimination interventions were implemented.
