All Plasmodium falciparum articles
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NewsExperimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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NewsClimate change linked surge in malaria transmission could be less than feared
Despite concerns about the potential impact of climate change on increasing malaria risk, there is still limited understanding of how temperature affects malaria transmission – until now.
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NewsStudy reveals impact of malaria interventions through routine sampling of pregnant women
Genomic analysis of the malaria parasite in pregnant women attending their first antenatal visit revealed reduced diversity in areas of southern Mozambique where elimination interventions were implemented.
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NewsMalaria parasite generates genetic diversity using evolutionary ‘copy-paste’ tactic
Plasmodium falciparum, a malaria parasite, uses gene conversion to produce genetic diversity in two surface protein genes targeted by the human immune system.
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NewsResearchers discover that blocking an essential nutrient inhibits malaria parasite growth
Researchers have found that by preventing the malaria parasite from scavenging fatty acids, a type of required nutrient, it can no longer grow.
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NewsStudy supports potential for injectable ‘chemical vaccine’ for malaria using atovaquone
Researchers demonstrate in mouse model that key mutation that renders malaria parasites resistant to atovaquone also makes them non-transmissible via mosquitoes.
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NewsMainstay malaria drug may be beginning to fail in the Horn of Africa
In eastern Africa, malaria parasites have developed resistance to artemisinins, the backbone of current treatment regimens, a development that could dramatically worsen malaria’s impact if partner drugs fail in the future.
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NewsTargeting malaria parasite’s IncRNAs could halt life cycle progression
A study into mechanisms that regulate gene expression through the different stages of Plasmodium falciparum’s lifecycle could open new avenues for therapeutic strategies aimed at stopping the parasite’s life cycle progression.
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CareersUncovering the secrets of the mummy
To his great surprise, microbiologist Frank Maixner found himself turning his scientific skills to mummy research. He reveals what the latest techniques are revealing about ancient humans, the history of malaria and the Medici family.
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NewsNon-invasive technology tests for malaria without a blood sample
A novel testing platform under development by researchers at the Yale School of Public Health (YSPH) and CytoAstra, LLC could provide a new noninvasive test for malaria that doesn’t require a blood sample.
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NewsGene expression in apicoplast could be target for malaria treatment
Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum is regulated by melatonin in host blood, and intrinsic parasite cues, via a factor called ApSigma, a recent study reveals.
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NewsDrugs targeting malaria in Mozambique are still effective
The drugs used to treat and prevent malaria in Mozambique are still effective, according to a genomic analysis of drug resistance markers in Plasmodium falciparum, carried out by the Barcelona Institute for Global Health (ISGlobal) and the Manhiça Health Research Center (CISM). Source: CDC/ Dr. Mae Mellvin Photomicrograph ...
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NewsMalaria pathogen found in mummified soft tissue in Medici tomb
The pathogen of the deadliest form of the disease has been identified in mummified soft tissue belonging to members of the Florentine dynasty.
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NewsTraditional medicine plant could combat drug-resistant malaria
Researchers have identified compounds in the leaves of a particular medicinal Labrador tea plant used throughout the First Nations of Nunavik, Canada, and demonstrated that one of them has activity against the parasite responsible for malaria.
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NewsSecond gene implicated in malaria chloroquine resistance evolution
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, scientists have shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
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NewsScientists uncover what makes malaria such a wily foe
Researchers have created the first high-resolution map of the human immune response to Plasmodium falciparum, offering insight into what makes this parasite such a persistent pathogen.
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NewsResearchers uncover how new class of antimalarial compounds can target parasite
Researchers at Imperial College London, UK, have discovered how a new class of antimalarial compounds can target and kill the malaria parasite in a unique way.
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