All pneumonia articles
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NewsImmune drug anifrolumab linked to lower risk of infection and hospitalization for skin lupus
Preliminary results from an investigator-initiated single-site clinical study show that some people with chronic cutaneous lupus erythematosus are less likely to acquire life-threatening infections when taking the drug anifrolumab.
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NewsFor Legionella bacteria, taking over a cell means playing by its rules
New research demonstrates how a protein produced by Legionella mimics the behavior of the host cell’s own proteins.
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NewsDelayed antiviral immune responses in alveolar cells increases susceptibility to influenza virus
A new study finds alveolar type 2 cells mount slower interferon-driven antiviral defenses than type 1 cells, enabling higher viral replication during influenza infection.
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NewsDiscovery of severe pneumonia subtypes could lead to tailored treatments for life-threating disease
New research shows that severe pneumonia has three different subtypes, helping explain why some patients in intensive care units (ICUs) recover quickly, while for other patients the disease can be life-threatening.
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NewsInfections are major ‘health hazard’ for people with diabetes
Infections should be considered a “health hazard” in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but under-recognised burden of illness, hospitalisation and death. People living with type 1 diabetes, type 2 diabetes and prediabetes face higher risks of infection compared to those without diabetes.
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NewsNASCAR star’s death shows how sepsis can kill anyone if not caught
Kyle Busch won more races than any driver in NASCAR history. But his own race ended far too soon, cut short by sepsis at the age of 41 after a case of pneumonia.
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NewsGut microbiota impacts resistance to bacterial pneumonia: Study
A gut-lung connection influences susceptibility to infection by Acinetobacter baumannii, according to a new study. Investigators found that antibiotics disrupt the gut microbiota, suppress protective immune system pathways in the lungs; and increase the severity of pneumonia.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsChildren with sleep apnea face higher risk of flu and COVID-19, new study finds
A five-year study has revealed that children with sleep apnea are twice as likely to contract the flu or COVID-19, regardless of their age or weight. Even after undergoing surgery to remove tonsils or adenoids, this increased vulnerability persists due to long-term changes in the immune system.
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NewsPediatric investigation study reports significant shifts in post-COVID respiratory infection trends in children
To explore how the pandemic changed respiratory infection trends in children, researchers examined data from 73,096 pediatric patients hospitalized with acute respiratory tract infections in two coastal cities in eastern China with similar climates.
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NewsNew tool shows how to enter and change pneumocystis fungi
Researchers have reported success in genetically modifying the fungal pathogen Pneumocystis murina. Their approach uses extracellular vesicles from mouse lungs to deliver gene-modifying molecules inside the fungal cells. The modified fungus expressed the introduced genomic modifications.
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NewsA new way to diagnose deadly lung infections and save lives
Researchers have found a way to identify lung infections in critically ill patients by pairing a generative AI analysis of medical records with a biomarker of lower respiratory infections.
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NewsIn pneumonia’s tug-of-war, lung microbiome could tip the balance
Scientists have found the lungs’ own microbial community, or microbiome, appears to influence how pneumonia evolves, who responds well to treatment and whether a patient will recover successfully or continue to deteriorate.
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NewsHuman ‘mini-noses’ help understand why RSV infections are more severe in children than in adults
Why does RSV affect babies more severely? To better understand the cellular reasons behind this age-related difference, researchers compared infant and adult human nose organoids, also called mini-noses, regarding their susceptibility and response to infection.
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NewsResearchers identify bacterial enzyme that can cause fatal heart conditions with pneumonia infections
Researchers have identified a bacterial enzyme that may be the reason some people get heart complications with pneumonia, while others do not. Since enzymes create chemical reactions to help bacteria survive, grow, and sometimes attack tissues, zmpB could become a target for future therapies.
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NewsCorticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia
A systematic review and meta-analysis found that adjunct corticosteroids probably reduce short-term mortality in cases of severe pneumonia and acute respiratory distress syndrome and may reduce secondary shock in severe pneumonia.
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NewsNew study shows invasive Group A Streptococcus outcomes shaped by treatment strategies, not species lineage
Researchers highlight the role of early clindamycin prescription in improving the recovery rate of patients with invasive Group A Streptococcus infections in a study that examined the evolving epidemiology of such infections.
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NewsScientists pinpoint optimal dose of methylprednisolone for treating severe Mycoplasma pneumoniae pneumonia
Investigators have compared the efficacy of low- versus high-dose of methylprednisolone in preventing pulmonary lesions in children with severe Mycoplasma pneumoniae pneumonia.
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NewsFlightpath Biosciences licenses microbiome-sparing antibiotic developed at Illinois
Flightpath Biosciences, Inc., has licensed a class of antibiotics developed at the University of Illinois Urbana-Champaign. The original antibiotic agent, lolamicin, effectively treated bacterial infections in animal models of disease without wiping out beneficial gut microbes.
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NewsVaccination support program reduces pneumonia-related mortality by 25 per cent among the elderly
Findings based on efforts in Sera Town, Japan showed the pneumococcal vaccination support program reversed the previously increasing trend in pneumonia mortality rate in the community.