All Pseudomonas aeruginosa articles – Page 2
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NewsImplantable living materials autonomously deliver therapeutics using contained engineered bacteria
Researchers have introduced an implantable “living material” that contains bacteria that sense infections. It can release these therapeutic molecules on demand, while keeping them physically separated from the surrounding tissue.
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NewsResearchers find increased bacteria infection in patients with chronic lung disease
A new study has found that people with bronchiectasis and chronic sinus disease were more likely to have mucus samples that tested positive for Pseudomonas aeruginosa. It suggests that doctors caring for patients with bronchiectasis may need to pay closer attention to sinus disease and bacterial testing.
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NewsAI speeds chemists’ search for better disinfectants
Scientists published their computational-experimental framework for developing quaternary ammonium compounds, or QACs, to kill bacteria. The method yielded 11 new QACs that show activity against antimicrobial-resistant bacteria.
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NewsA universal toolkit for editing bacterial DNA
A major collaboration involving nine labs has transferred a particularly useful DNA editing system from E. coli into 14 new species of bacteria, spanning three major branches of the bacterial family tree.
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NewsResearchers disable antimicrobial resistance in cystic fibrosis-associated bacteria
A newly discovered mechanism renders antibiotic-resistant bacteria vulnerable by disabling both their individual resistance and a process known as cross-protection, the ability of resistant bacteria to shield nearby, otherwise sensitive strains.
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NewsResearchers uncover how obesity impairs vaccine response
New findings reveal that obesity significantly impaired the quality and longevity of antibody responses to a Pseudomonas aeruginosa vaccine in a mouse model. The impaired antibody production was due to defects in germinal centers.
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NewsSurface treatment of wood may keep harmful bacteria at bay
A recent study suggests that bacteria thrive more readily on untreated than treated wood surfaces. The finding has implications for hygiene in both homes and public spaces.
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NewsNitrous oxide, a product of fertilizer use, may harm some soil bacteria
While some nitrous oxide is produced naturally at the plant root, agricultural practices can increase its levels. While it has long been believed that nitrous oxide doesn’t meaningfully interact with living organisms, a new paper shows that it may in fact shape microbial communities.
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NewsNew insights into how bacteria control DNA synthesis open the door to next generation antimicrobials
A new study combines structural biology, biophysical characterisation and functional assays to delineate how the bacterial transcriptional regulator NrdR’s quaternary structure responds to different nucleotide states and how these changes affect its regulatory activity.
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NewsA mint idea becomes a game changer for medical devices
Researchers have developed a high‑performance coating made from peppermint essential oil that can be applied to the surfaces of many commonly used medical devices, offering a safer way to protect patients from infection and inflammation.
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NewsEarly translational study supports the role of high-dose inhaled nitric oxide as a potential antimicrobial therapy
Researchers report that high-dose inhaled nitric oxide (iNO) demonstrates potential antimicrobial activity in preclinical models and is safe and feasible in early human studies, supporting further clinical investigation.
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NewsNew study shows how light suppresses virulence in antibiotic-resistant pathogen
Researchers uncover a light-sensitive signaling cascade in Pseudomonas aeruginosa that suppresses biofilm formation and virulence, offering a potential new strategy to combat antibiotic-resistant infections.
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NewsGolden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages
Researchers have described the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.
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NewsA gentler way to model deadly lung infections in old age
Researchers report a refined mouse model that successfully mimics chronic Pseudomonas aeruginosa lung infection in old age. The study introduces an agar bead-based delivery strategy that allows bacteria to persist in the lungs of aged mice without causing rapid death.
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NewsTraditional herb offers new hope for antibiotic-free pig farming
A new review highlights that Houttuynia cordata extract could serve as a multifunctional natural substitute for antibiotics in swine production. Plant-derived flavonoids, volatile oils, and polysaccharides suppress pathogens including Salmonella, PRRSV, and Streptococcus suis.
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NewsViruses in wastewater: Silent drivers of pollution removal and antibiotic resistance
New findings suggest that current monitoring strategies, which rely heavily on bacterial indicators alone, may miss critical viral-driven risks and opportunities for safer wastewater reuse.
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NewsStudy reveals how bacteria resist hostile attacks from rival bacteria
When attacked by bacteria from a different species, Pseudomonas rapidly assembles the type VI secretion system (T6SS) – to inject its aggressor with a toxic cocktail. A new study probes how Pseudomonas can strike back when it has already been hit by a deadly cocktail itself.
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NewsPositive signs in the fight against superbugs: CHINET 2024 surveillance report
The 2024 CHINET antimicrobial resistance surveillance report uncovers a hopeful trend in China’s battle against bacterial resistance, with a significant reduction in resistance among several key pathogens.
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NewsParkinson’s drug offers basis for new hospital bacterium anti-infectives
Researchers have discovered a promising starting point for the development of new active substances against the hospital germ Pseudomonas aeruginosa.
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NewsExperimental mRNA therapy shows potential to combat antibiotic-resistant infections
Researchers have reported early success with a novel mRNA-based therapy designed to combat antibiotic-resistant bacteria. In preclinical studies, the therapy slowed bacterial growth, strengthened immune cell activity, and reduced lung tissue damage in models of multidrug-resistant pneumonia.