All Pseudomonas aeruginosa articles – Page 2
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Sophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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Overcoming resistance: McMaster researchers find new utility for old antibiotics
In a recent study, researchers found that zinc plays a vital role in how some of the world’s most dangerous bacteria resist antibiotics.
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Diverse phage populations coexist on single strains of gut bacteria
A new study shows that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Several phage species coexist stably on a population of a genetically uniform strain of E. coli.
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Histones show promise against bacterial infections
Scientists have outlined that human histones have antimicrobial activity against different bacteria, including biofilms of Pseudomonas aeruginosa, one of the six most resistant bacteria in the world.
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A lung pathogen’s dilemma: infect or resist antibiotics?
Research has uncovered how Pseudomonas aeruginosa manages the trade-off between colonizing and surviving during infection by switching between biofilm formation for antibiotic protection and a more mobile, “planktonic” state to spread and access nutrients.
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Structural biology analysis of a Pseudomonas bacterial virus reveals a genome ejection motor
Bacterial viruses, known as phages, are the most abundant biological entities on the planet and are increasingly used as biomedicines to eradicate antibiotic-resistant pathogenic bacteria.
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Chemists pioneer metallodrug-antibiotic combination strategy to combat superbugs
A combination of different types of antibiotics with bismuth-based drugs, such as Pepto-Bismol, disrupts bacterial iron homeostasis, effectively restoring the bactericidal function of multiple antibiotics.
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$7 Million grant to tackle lung infections through innovative probiotic treatment
The PROTECT project seeks to combat lung infections by assembling a community of beneficial lung microbes that can outcompete harmful pathogens.
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New discovery of how bacteria navigate their environment could change how we treat infection
Scientists have found that bacteria can directly measure differences in chemical concentration across the length of their cell bodies, contrary to decades of established scientific belief.
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Hydrometeorology and location affect hospitalizations for waterborne infectious diseases in the US
An analysis of 12 years of data collected from over 500 hospitals in 25 different states shows that weather, geographic location, and urban or rural location all appear to influence hospitalizations for waterborne infectious diseases.
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Peptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Discharge of untreated hospital effluent is a key driver of multidrug resistance, study finds
A new study has highlighted the discharge of untreated hospital effluent to the environment as a major driver of multidrug resistance among the microbial community.
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Scientists map how deadly bacteria evolved to become epidemic
Pseudomonas aeruginosa evolved rapidly and then spread globally over the last 200 years, probably driven by changes in human behaviour, a new study has found.
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Treatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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Researchers thwart resistant bacteria’s strategy
Researchers have discovered a weakness in Pseudomonas aeruginosa with the potential to become the target for a new way to attack it.
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Two types of polymicrobial infections in chronic lung diseases
Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study team led by MedUni Vienna has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment. The study was published in the journal ...
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Lung organoids unveil secret of how pathogens infect human lung tissue
Using human lung microtissues, researchers have uncovered the strategy used by a dangerous pathogen to invade the lungs. Pseudomonas aeruginosa targets specific lung cells and has developed a sophisticated strategy to break through the lungs’ line of defense.
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Novel triple antibiotic combination offers breakthrough in combatting antibiotic resistance
A new study unveils a promising triple combination of antibiotics that significantly expands our arsenal against drug-resistant bacteria.
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Squeaks the cat makes full recovery after personalized phage therapy heals resistant wounds
A new study highlights the potential of phage therapy as an effective solution for antibiotic-resistant infections in veterinary practice, resulting in the complete healing of a persistent surgical wound after fourteen weeks.