All Public Health articles – Page 4
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Gene-delivering viruses cross into brain in step toward gene therapy for neurological diseases
A family of adeno-associated viruses (AAVs) has been developed that are capable of delivering gene therapies to the brain, a particularly challenging target tissue.
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Hospitals are riskier than farms when it comes to superbug transmission - but beware your pet
A deadly drug resistant bacterium that rivals MRSA is found in livestock, pets and the wider environment, but is rarely transmitted to humans through this route, scientists have found.
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Vibrio toxins force key proteins to build ‘roads to nowhere’
Toxins released by a type of bacteria that cause diarrhoeal disease hijack cell processes, forcing important proteins to abandon jobs that are key to proper cell function and assemble into ’roads to nowhere’, a new study has found.
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COVID-19 reanimates latent viruses in cells – particularly in ME patients
Researchers have found that COVID-19 reactivates viruses that had become latent in cells following previous infections, particularly in people with chronic fatigue syndrome, also known as ME/CFS.
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Antibiotic resistant microbes in gut make C difficile more infectious
Scientists have found that Enterococcus – an antibiotic-resistant, opportunistic pathogen – works together with Clostridioides difficile in the human gut, reshaping and enhancing the metabolic environment in the gut so that C. difficile can thrive.
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Bacteria behind biblical disease have potential to regenerate livers
Scientists have discovered that the bacterium that causes leprosy can reprogramme cells to increase the size of a liver in adult animals without causing damage, scarring or tumours.
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Probiotic ‘backpacks’ could treat inflammatory bowel diseases
Researchers have devised specialised nano-particles that can neutralise molecules linked to inflammatory bowel disease (IBD), and can be attached to beneficial probiotic bacteria targeting the gut.
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Restoring the gut biome after antibiotics could lead to better outcomes for ovarian cancer patients
Antibiotics routinely used in ovarian cancer care indiscriminately kill gut bacteria, leading to faster cancer progression and lower survival rates, according to recent Cleveland Clinic research.
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Monkeypox mutations cause virus to spread rapidly and dodge vaccines
Researchers at the University of Missouri have identified the specific mutations in the monkeypox virus that contribute to its continued infectiousness.
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Gull droppings undermine efforts to control spread of colistin-resistance genes
Gull droppings at beaches in the Porto region of Portugal are riddled with bacteria that are resistant to the ‘last-resort’ antibiotic colistin, undermining efforts in the livestock sector to reduce colistin-resistance, according to a paper published in Environmental Microbiology, an Applied Microbiology International publication. Researchers at the ...
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New method offers real time monitoring of gut microbiome
Researchers have found a simple and innovative way to examine the intestinal bacteria of the human small intestine to show how they support the digestive process by reacting dynamically to the human nutritional status.
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Gut bacteria can enhance the effects of cocaine in mice
Common gut bacteria can enhance the effects of cocaine in mice, researchers report.
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Identity theft revealed as the secret of cat parasite’s success
Researchers at Stockholm University have discovered how the microscopic parasite Toxoplasma so successfully spreads in the body by infecting immune cells and hijacking their identity.
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Researchers find SARS-CoV-2 Omicron BA.2 subvariant less severe than earlier variants
team led by investigators at Massachusetts General Hospital (MGH) has determined that the SARS-CoV-2 Omicron BA.2 subvariant is less severe than the previous Delta variant and less severe to an even greater extent than the original Omicron variant.
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Controlling gut flora can reduce mortality in critically ill patients on life support
Preventing severe lung infections in mechanically ventilated intensive care patients by applying topical antibiotics to the upper digestive tract results in a clinically meaningful improvement in survival, new research shows.
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New drug is effective for treating complicated urinary tract infections
Researchers who compared new and older treatments for complicated urinary tract infections have found a new drug combination to be more effective, especially against stubborn, drug-resistant infections.
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UC San Diego launches new Human Milk Institute
The University of California San Diego has launched a new Human Milk Institute (HMI) to accelerate research into the nature, biology and therapeutic potential of human milk to prevent or treat both infant and adult diseases.
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Researchers shed light on the virulence of Staphylococcus lugdunensis in children
Researchers have identified that Staphylococcus lugdunensis is a rising cause of central nervous system infections associated with the ventriculoperitoneal shunting procedure, especially in children.
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Intranasal COVID vaccine works against variants in animals
Researchers have developed an intranasal vaccine against Covid-19 that can fight off the original virus and two variants in hamsters.
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Nicotine-degrading bacteria protects against smoking-related liver disease in mice
A gut bacterium capable of breaking down nicotine and protecting against smoking-related fatty liver disease progression in a mouse model has been identified in a Nature paper.