All Research News articles – Page 88
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Scientists warn of overuse of antibiotics in newborns with suspected sepsis
Newborns in Sweden are given antibiotics for suspected sepsis to an unjustified extent, reveals a study of more than one million newborns. Despite a significant reduction in sepsis rate in the group, the use of antibiotics has not decreased.
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Gut bacteria metabolite shows promise for fighting inflammatory bowel disease
A new study highlights the molecular mechanisms underlying the anti-inflammatory effects of KetoC, a gut bacteria-generated linoleic acid metabolite, using mouse models.
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Tenofovir alafenamide treatment achieves positive results in Chinese chronic hepatitis B patients
A five-year treatment regime with tenofovir alafenamide achieves high rates of viral suppression, alanine aminotransferase normalization, and favorable bone and renal safety in Chinese chronic hepatitis B patients.
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Key role found for gut epithelial cells in the defense against deadly diarrheal infections
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.
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Transfected SARS-CoV-2 spike DNA suppresses cancer cell response to chemotherapy
Researchers have examined the interaction between SARS-CoV-2 spike, p53 and MDM2 (E3 ligase, which mediates p53 degradation) in cancer cells using an immunoprecipitation assay.
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Progression of herpesvirus infection remodels mitochondrial organization and metabolism
Researchers have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell. The new information will help to understand the interaction between herpesvirus and host cells.
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Researchers discover link between breast changes and UTIs
Scientists have found that UTIs in mice can provoke a bodily response that results in structural changes in breast tissue. Remarkably, these changes are reversible once the infections are resolved.
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Genomes of ‘star algae’ shed light on origin of land plants
An international group of researchers has generated the first genome data of on four filamentous ‘star algae’ of the genus Zygnema - among the most closely related to land plants.
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Analysis of flour and rice in Brazil shows high levels of harmful fungal toxins
The foods, found in the homes of Brazilian families participating in the research, were stored for future consumption. The study is the first in Brazil to use biomarkers to characterize the risk associated with mycotoxins in the diet.
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Geologists and biologists unearth atomic fingerprints of cancer using fermenting yeast
Researchers have discovered that cancer cells may be made from a different assortment of hydrogen atoms than healthy tissue, findings which could give doctors new strategies for studying how cancer grows and spreads.
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Study identifies immunity threshold for protection against COVID-19 in children
Researchers have found rather than antibodies, other arms of the immune system – T cells and memory B cells – provide durable protection against symptomatic SARS-CoV-2 infection in children.
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Study finds diabetes drug reduces COVID-19 viral load and viral rebound
Researchers have found that metformin, a drug commonly used to treat diabetes, can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after initial treatment.
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Microbiome studies help explore treatments for genetic disorders
Researchers have discovered a collection of molecular tools to rewrite DNA through an even more efficient and precise genome editing process. They are investigating the clinical development of a group of enzymes for sub-retinal injections.
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Researchers discover compounds produced by gut bacteria that can treat inflammation
Researchers have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.
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How E. coli get a foothold to cause urinary tract infections
New research examines how the bacteria Escherichia coli—responsible for most UTIs—is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.
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For microscopic organisms, ocean currents act as ‘expressway’ to deeper depths
New research shows how tiny plant-like organisms hitch a ride on ocean currents to reach darker and deeper depths, where they impact carbon cycling and microbial dynamics in the subtropical oceans.
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Scientists reveal search for faster way to diagnose MRSA and its relatives
New research being presented at the Letters in Applied Microbiology ECS Symposium reveals the drive to come up with a better way of diagnosing staph infections that would be more cost-effective and less time-consuming.
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In medieval England, leprosy spread between red squirrels and people, genome evidence shows
Evidence from archaeological sites in the medieval English city of Winchester shows that English red squirrels once served as an important host for Mycobacterium leprae strains that caused leprosy in people, researchers report.
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Source of pregnancy complications from infections revealed by placenta map
The first panoramic view of infection pathways in the human placenta has been created, which could highlight potential drug targets to develop pregnancy-safe therapies for malaria, toxoplasmosis and listeria.
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Rotavirus vaccinations in NICU pose minimal risk, study reveals
Rotavirus vaccines do not cause significant outbreaks of the disease in neonatal intensive care units (NICUs), according to a new study.