Research – Page 18
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Backyard poultry face HPAI risk when migrating mallards stop to rest
Knowing where, when and for how long mallard ducks – natural carriers of avian influenza – stop and rest as they migrate can help predict the probability that they will spread bird flu to backyard poultry flocks, according to a new study.
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Research suggests common viral infection worsens deadly condition among premature babies
Researchers say they found that infection with a common virus that can be transmitted from mother to fetus before birth significantly worsens an often-fatal complication of premature birth called necrotizing enterocolitis (NEC) in experiments with mice.
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Study uncovers porcine reproductive and respiratory syndrome virus’s impact on swine immunity
Scientists used single-cell RNA analysis to reveal key immune mechanisms in lungs of swine infected with PRRSV. They found higher numbers of protective anti-inflammatory M2-like macrophages (SPP1-CXCL14high) were observed in less virulent infections, suggesting a potential role in promoting lung healing.
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Scientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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Stealth virus: Zika virus builds tunnels to covertly infect cells of the placenta
Researchers have discovered that Zika virus in the placenta builds underground tunnels, a series of tiny tubes called tunneling nanotubes, that facilitate the transfer of viral particles to neighboring uninfected cells.
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Promising antibody may prove useful against deadly Ebola virus outbreaks
New research reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus therapeutics.
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Nitrogen fixation on marine snow particles is widespread in the world's oceans
Researchers have shown that bacteria attached to marine snow particles can fix N2 over a wide range of temperatures in the global oceans, from the tropics to the poles, and from the surface to the abyss, accounting for about 10% of the overall N2 fixation in oceans.
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Promising new class of antimalarial drugs discovered
A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen. The chromatin remodeler PfSnf2L is a key regulator of genes that play an important role in various stages of the pathogen’s development.
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Study calls for better measures of poverty to strengthen tuberculosis research
A new review examines existing methods for assessing socioeconomic status in TB studies and highlights their shortcomings. The authors call for better, standardized poverty metrics to improve research and policy.
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Chlorine plus UV light degrades toxins caused by harmful algae blooms
Scientists examining the combination of ultraviolet light and chlorine to detoxify water laden with toxins from cyanobacteria have demonstrated that this combination significantly enhanced the degradation of toxins compared to chlorine alone.
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Paxlovid’s impact on hospitalization and death in COVID-vaccinated older adults far weaker than previously thought
A new study overturns the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.
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Groundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials. The mRNA vaccine was successful in triggering an immune defence response that helped to reduce TB numbers in infected mice.
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Scientists warn of increased mpox transmission
International researchers warn that the ongoing mpox outbreak in the Democratic Republic of the Congo (DRC) has the potential to spread across borders more rapidly. The mpox virus has mutated, and the new variant, clade 1b, has become more infectious.
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Scientists uncover how bacterial resistance to synergistic drug treatments is arising
Scientists investigating the potential of combined and more powerful drug treatments have found that antimicrobial resistance to these is arising via the vitamin B2 synthesis pathway.
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Blocking plant immune responses gives colonizing bacteria a competitive advantage
Similar to pathogens, commensal bacteria of plant microbiota were found to possess the mechanism to suppress plant immunity that allows their competitive advantage over non-immunosuppressive bacteria amongst the root-associated bacterial community.
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New therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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Feed additives can reduce campylobacter in free-range broilers
Trials have demonstrated that adding biochar to chicken feed can significantly reduce campylobacter in chickens, which could potentially lead to fewer campylobacter-associated foodborne diseases in humans.
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Neonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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Resilient algae may speed up Greenland ice melt
Microscopic algae darken glacier surfaces and can accelerate melting. A new study investigating where the small algae get the necessary nutrients to survive in this hostile environment reveals how they absorb and store nutrients.
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Expedition confirms spread of highly pathogenic avian influenza virus in the Weddell Sea
The CSIC-UNESPA scientific expedition monitoring the presence of the highly pathogenic avian influenza virus (HPAI H5N1) in Antarctica has confirmed the presence of the virus in all species detected on six islands in the Weddell Sea.