Research – Page 27
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New paper creates roadmap for the next generation of bioelectronic medicine
A new paper offers a roadmap to the future of bioelectronic medicine — which makes use of electrical signals instead of drugs to diagnose and treat disease.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Human papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
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Biotin may shield brain from manganese-induced damage, study finds
New research showing the mechanisms by which manganese inflicts damage to the central nervous system suggests that the vitamin biotin - synthesized by gut bacteria - may have a protective effect, potentially mitigating manganese-induced damage.
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Global trust in science remains strong after pandemic
A post-pandemic global survey reveals that the general public remains to perceive scientists as trustworthy. They are also encouraged to actively engage in public communication and address the areas researches should prioritize in.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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Cycle of coral bleaching on the Great Barrier Reef now at ‘catastrophic’ levels
Marine scientists have published the first peer-reviewed study documenting the devastating coral bleaching events that occurred on the southern Great Barrier Reef in early 2024. 66 per cent of the colonies were bleached by February 2024 and 80 per cent by April.
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Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A promising research study in treating high mortality late-stage cancers with a non-toxic bacterial therapy - BacID - has proven to be safe and more targeted. The newly developed treatment would undergo clinical trials with cancer patients in 2027.
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Sophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.
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Bacteria in polymers form cables that grow into living gels
Scientists have discovered that bacterial cells growing in a solution of polymers, such as mucus, form long cables that buckle and twist on each other, building a kind of “living Jell-O.”
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Extreme rain heightens E. coli risks for communities of color in Texas
New research shows that communities of color in Texas face pronounced risks of E. coli exposure in nearby waters following storms that dump abnormally high amounts of rain.
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Machinery behind bacterial nanowires discovered
Almost all living things breathe oxygen to eliminate the excess electrons produced when nutrients are converted into energy. However, most microbes that mitigate pollution and climate change don’t have access to oxygen. Instead, these bacteria—buried underground or living deep under oceans—have developed a way to eliminate electrons by “breathing minerals” ...
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Bioactive compounds with possible industrial applications are identified in extremophilic bacteria from the Andes
Researchers isolated a strain of Pseudomonas alcaligenes that can withstand temperatures as high as 44 °C from a hot spring in Chile, and characterized the substances produced by the bacterium that help it survive extreme conditions.
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New study provides insight into how some species thrive in dark, oxygen-free environments
A new study sheds light on how a species of foraminifera, single-celled organisms found in almost all marine habitats, thrives in a dark, oxygen-free environment.
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Researchers team with dogs to discover new truffle species
Researchers have discovered two new species of truffle. Tuber canirevelatum, meaning the ‘dog-found’ truffle, was named in honor of truffle dogs. The other, Tuber cumberlandense, was named for the Cumberland Plateau where it was found.
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Gene-edited soil bacteria could provide third source of nitrogen for corn production
If corn was ever jealous of soybean’s relationship with nitrogen-fixing bacteria, advancements in gene editing could one day even the playing field. A recent study from the University of Illinois Urbana-Champaign shows that gene-edited bacteria can supply the equivalent of 35 pounds of nitrogen from the air during early corn ...
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Oral cancer and microbiome: new insights into tumor growth mechanisms
A recent study has made significant strides in uncovering how the oral microbiome plays a crucial role in the progression of oral squamous cell carcinoma (OSCC), unveiling metabolic pathways and mechanisms that may serve as potential therapeutic targets.
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Study takes stock of the known and unknown microbial space
Using publicly available genome sequence data generated over the past three decades, a new study assesses what fraction of the microbial diversity we know about, and proposes a path forward to curate and cultivate what is still unknown.