All Ruhr University Bochum articles
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News
Researchers detect hepatitis viruses in wastewater
High-throughput sequencing of river water samples showed that it is possible to identify different genetic variants of the hepatitis E virus in wastewater.
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Mutating hepatitis viruses make drug treatment more difficult
Sofosbuvir and Ribavirin combination therapy efficiently decreased viral RNA in blood and stool in patients with chronic HEV infection, but variants that are associated with antiviral resistance emerged during treatment.
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New method builds fluorescent nanotubes to detect bacteria and viruses
Researchers have developed a new approach to construct modular optical sensors which are capable of detecting viruses and bacteria.
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Single hepatitis E mutation renders sofosbuvir therapy ineffective
A single mutation of the hepatitis E virus has been shown to cause treatment with the hepatitis C drug sofosbuvir to become much less effective, according to a study that provides new insights for future drug development.
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Monkeypox virus remains stable on surfaces for days
Researchers warn that it is extremely important to disinfect surfaces to decrease the risk of monkeypox in the event of an outbreak.
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Scientists unlock indole in soil bacteria to create prodrugs
Researchers from Bochum and Leipzig have successfully used a soil bacterium to specifically produce prodrugs. The key to this step was a detailed understanding of the metabolisation of indole, a natural compound which first must be activated in microorganisms. To do this, they needed a monooxygenase, the molecular structure of ...
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Spotlight on how hepatitis E is able to infect cells
A recently developed cell culture model has finally made it possible for researchers to investigate how hepatitis E is able to infect cells.
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Increase in multidrug-resistant pathogens since Ukraine war
Researchers in Germany have recommended screening patients from Ukraine for multi-drug resistant pathogens prior to hospital admission following a series of outbreaks.
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Researchers modify hydrogen-producing enzyme to protect it from oxygen destruction
Researchers have genetically modified a hydrogen-producing enzyme so that it is protected from oxygen, countering a key barrier to producing molecular hydrogen with enzymes from bacteria and algae.