All Scripps Research articles
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The very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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Researchers release phage images with unprecedented detail
Researchers have produced the most detailed image to date of a bacteriophage, that has allowed them to see for the first time the structural makeup of the part of the phage that directly attaches to its target Mycobacterium cell.
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‘Low-sugar’ vaccine can provide broad immunity against coronavirus variants
A universal vaccine for coronaviruses removes sugar molecules from an area of a coronavirus spike protein that rarely mutates and creates effective and plentiful antibodies to inactivate the virus.
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Chain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.
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Researchers use biophysics to design new vaccines against RSV and related respiratory viruses
Scientists improved existing vaccines by analyzing the molecular structure and stability of viral proteins.
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Genetic tracing at the Huanan Seafood market supports COVID animal origins
A study provides a list of the wildlife species present at the market from which SARS-CoV-2 most likely arose in late 2019, based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).
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Wearable health sensors are a powerful tool in disease detection
When seemingly healthy people receive an alert from a wearable sensor telling them they might have a respiratory virus, only a quarter of people follow up such an alert with an at-home viral test, according to a new study.
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Drug-like inhibitor shows promise in preventing flu
Scientists have developed a potential drug-like molecule that blocks the first stage of type A influenza infection.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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Study reveals new approach for combatting “resting” bacteria
Blocking long phosphate molecules could eventually help treat chronic infections in which slow-growing bacteria evade typical antibiotics.
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Scientists reveal how first cells could have formed on Earth
A new phospholipid discovery brings researchers closer to understanding how primordial cells emerged during origin of life.
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Calibr announces license agreement with Gilead to develop long-acting HIV antiviral agent
Long-acting combination HIV regimens have the potential to transform the future of coordinated HIV clinical care
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Scientists reveal inner workings of Ebola’s ‘viral factories’
A new study reveals how the Ebola virus’s replication machinery forms fascinating microscopic structures inside host cells that become viral factories.
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Deadly virus structures pinpoint new targets for Lassa vaccine design
By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a research team has identified new antibodies and vaccine targets.
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Scripps Research scientists map key protein structure of Hepatitis C virus
Scientists have mapped critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.