All STIs articles
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Potential first new antibiotic for gonorrhoea since the 1990s is effective and safe, finds trial
Gepotidacin could be a new treatment to treat gonorrhoea, protecting against the threat of treatment-resistant gonorrhoea and improving patient treatment experiences, suggests the results of a phase 3 randomised control trial.
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New antibiotic for multidrug resistant superbug triggers suicide mechanism
Researchers have discovered a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhoea.
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Study yields new data on Mpox vaccine effectiveness in people with HIV
A new study has found that a single dose of the Imvanex vaccine provides protection against Mpox with 84% effectiveness. For people with HIV, however, a single dose of the vaccine fails to offer sufficient protection. All at-risk groups, especially people with HIV, should receive the second dose of the vaccine as recommended.
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New 3D imaging approach reveals intricate steps of virus assembly
A new integrated 3D imaging approach combines cryo-light microscopy and cryo-soft X-ray tomography to reveal the intricate ultrastructure of herpes simplex virus-1 (HSV-1) assembly.
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Scientists warn of increased mpox transmission
International researchers warn that the ongoing mpox outbreak in the Democratic Republic of the Congo (DRC) has the potential to spread across borders more rapidly. The mpox virus has mutated, and the new variant, clade 1b, has become more infectious.
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New method ‘fishes’ for bacterial STI DNA, revealing how Chlamydia spreads and adapts
Scientists have developed a cutting-edge “target enrichment” technology for bacterial STIs. Using specially designed molecular probes, they “fished” for bacterial STI DNA from clinical samples, enabling high-resolution genome analysis.
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Changes in microbiome predict risk for sexually transmitted disease
Researchers have found that bacterial vaginosis consists of two subtypes—one of which significantly increases the risk of developing chlamydia infections.
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As prevention strategy for sexually transmitted infections rolls out, experts highlight both promise and knowledge gaps
Real-world evidence demonstrates that the postexposure strategy of doxy PEP is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.
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New study shows plummeting STIs with doxyPEP use
A new study has found that rates of chlamydia and syphilis plummet among people prescribed doxycycline for sexually transmitted infection prevention in routine clinical care.
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Around 1 in 5 of the world’s under 50s living with genital herpes (HSV)
Around 1 in 5 of the world’s under 50s—846 million people—are living with genital herpes infection, and more than 200 million 15-49 year olds probably had at least one symptomatic outbreak of the infection in 2020, suggest the latest global estimates.
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Part of the GBHSH community in Spain uses doxycycline to prevent STIs
Researchers have carried out the first study in Spain on the use of DoxyPEP as a preventive strategy among the gay, bisexual and other men who have sex with men (GBHSH) community in Spain.
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Scientists uncover Chlamydia’s sneak attack strategies
Researchers have described the structural and functional methods Chlamydia pneumoniae uses to penetrate the human cell: It mimics molecular structures of the human cell (so-called “molecular mimicry”) and uses them for its attack.
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Scientists develop enzyme complex to find Achilles heel of protozoan parasite
In an effort to find a new weak spot of the protozoan parasite Trichomonas vaginalis, researchers have succeeded in preparing a key enzyme complex – the proteasome.
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Scientists reveal how doxycycline for STI prevention affects the gut microbiome
Taking a dose of the oral antibiotic doxycycline after a high-risk sexual encounter has dramatically reduced the incidence of sexually transmitted infections (STIs) in places where the strategy is being tried. Source: NIAID Capsules of the antibiotic doxycycline Despite its effectiveness, the new strategy, known ...
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Call for global gender-neutral HPV vaccination by 2030
A new global initiative is calling for a more ambitious, ethical and equitable approach that will see more boys and men gain access to cancer-preventing Human Papillomavirus (HPV) vaccination and protect more people worldwide from HPV-related cancers.
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Emergency department screening more than doubles detection of syphilis cases
Providing optional syphilis tests to most people seeking care at a large emergency department led to a dramatic increase in syphilis screening and diagnosis, according to a study of nearly 300,000 emergency department encounters in Chicago.
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NIH awards will support innovation in syphilis diagnostics
NIAID has awarded grants for 10 projects to improve diagnostic tools for congenital and adult syphilis—conditions currently diagnosed with a sequence of tests, each with limited precision.
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Scientists seek more effective treatment for under-the-radar STI
Researchers at Tulane University are leading a groundbreaking study to seek a more effective treatment for trichomoniasis, an infection that, despite being the most common curable sexually transmitted infection (STI) worldwide, continues to fly under the radar.
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Active substance identified for the prevention of chlamydial infections
Scientists screening active substances have identified pentamidine as potential prophylaxis against bacterial sexually transmitted diseases.
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Survey finds many have misconceptions about sexually transmitted infection risk
Sexually transmitted infections (STIs) are on the rise in the U.S., including an 80% increase in syphilis over a five-year period, but a new survey finds many Americans have misconceptions on how STIs are spread and who should be treated.