All t cells articles
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NewsHow food shortages reprogram the immune system’s response to infection
When food is scarce, stress hormones direct the immune system to operate in “low power” mode to preserve immune function while conserving energy. This reconfiguration is crucial to combating infections amid food insecurity.
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NewsCOVID-19 viral fragments shown to target and kill specific immune cells
New research shows that after the body’s defenses kill the virus behind COVID-19, leftover digested chunks of SARS-CoV-2 spike protein can target specific immune cells based on their shape. It could explain why certain populations of cells that detect and fight infection are depleted in patients with severe COVID-19.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsNew mechanism links Epstein-Barr virus to MS
Scientists investigating the links between the Epstein-Barr virus and multiple sclerosis show that when the immune system fights EBV, certain T cells – which normally attack the virus – can also react to a protein in the brain called Anoctamin-2 (ANO2), a phenomenon called molecular mimicry.
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NewsNew test could help pinpoint IBD diagnosis, study finds
A test that rapidly detects signs of inflammatory bowel disease (IBD) in stool samples could improve future diagnosis and monitoring of the condition, a study suggests. The luminescent reporter lights up when it detects a molecule linked to gut inflammation.
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NewsT cells take aim at Chikungunya virus
A new study offers the first-ever map of which parts of Chikungunya virus trigger the strongest response from the body’s T cells, bringing researchers closer to developing Chikungunya vaccines or therapies that harness T cells to strike specific targets to halt infection.
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NewsResearchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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NewsGut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study.
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NewsFrom Spanish flu to today: how immune cells keep up with a changing virus
In a breakthrough for influenza research, scientists have discovered immune cells that can recognise influenza (flu) viruses even as they mutate, raising hopes for a longer-lasting vaccine and a universal protection against future flu pandemics.
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NewsT cells’ capability to fully prevent acute viral infections opens new avenues for vaccine development
Scientists have discovered that T cells—white blood cells that can destroy harmful pathogens—can completely prevent viral infection, to an extent previously thought only possible due to neutralising antibodies.
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NewsNew therapeutic approach for severe COVID-19
A new clinical study shows that an inhibitor of Fas ligand, also called CD95 ligand, led to a faster recovery of COVID-19 patients and reduced mortality.
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NewsKey role found for gut epithelial cells in the defense against deadly diarrheal infections
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.
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News’Dormant’ HIV produces RNA and proteins during anti-retroviral therapy
Two independent groups of researchers report that a subset of ‘dormant’ HIV-infected cells spontaneously produce HIV RNA and proteins that may impact patients’ HIV-specific immune responses.
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NewsEngineered bacteria track down tumours, then signal the immune cells
Researchers have created a ’bacterial suicide squad’ that targets tumours, attracting the host’s own immune cells to the cancer to destroy it.
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NewsNorovirus may be linked to higher risk of developing Crohn’s Disease
A new study links Crohn’s disease to the common norovirus, a group of viruses that can cause gastroenteritis, an inflammation of the stomach and intestines.