All The Sex Issue articles
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U.S. Public Health Service releases new guidelines on occupational HIV exposure and postexposure prophylaxis
The CDC, on behalf of the U.S. Public Health Service (PHS), has released the 2025 Guidelines for the Management of Occupational Exposure to Human Immunodeficiency Virus (HIV) and Recommendations for Postexposure Prophylaxis (PEP).
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World-first koala chlamydia vaccine approved
In a world first, a vaccine has been approved to protect Australia’s endangered koalas from infection and death caused by chlamydia.
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One dose of antibiotic treats early syphilis as well as three doses
Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.
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Study looks for markers that predict risk of severe chlamydia infection
A new study has identified markers that may predict whether a chlamydia infection is likely to ascend into the uterus and endometrium. The work could lead to new diagnostics that can predict a woman’s risk of severe infection.
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Portable spectroscopy enables detection of vaginal microbes
Surface-enhanced Raman spectroscopy can rapidly and noninvasively detect specific bacterial species in vaginal fluid, enabling early identification of microbiome imbalances.
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Bird-to-human jump by trichomonas parasites illuminated in new study
A new study reveals how genetic changes in the parasite responsible for one of the world’s most common sexually transmitted infections may have helped it adapt to human hosts.
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Research reveals STIs during pregnancy linked to adverse birth complications
Common sexually transmitted infections during pregnancy have been linked to a higher risk of significant birth complications including preterm birth, stillbirth and babies born smaller than expected.
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Beetles under climate stress lay larger male eggs: Wolbachia infection drives adaptive reproduction strategy
Researchers find that azuki bean beetles, a common pest, produce larger eggs yielding male offspring when infected with Wolbachia bacteria under elevated temperature and carbon dioxide conditions.
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Scientists discover key protein that enables ‘shock & kill’ strategy for HIV latent virus clearance
Researchers have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.
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Rapid testing for sexually transmitted infections on the horizon
Birmingham spin-out Linear Diagnostics has been awarded £1m funding to finalise the development of a low-cost, accurate, near-patient diagnostic platform that aims to diagnose STIs from a single sample faster than any commercially available alternative.
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Proof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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‘Loop’hole: HIV-1 hijacks human immune cells using circular RNAs
In a groundbreaking discovery, researchers have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defenses and use it to support its survival and replication.
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Forever chemicals influence cellular immune response to coronavirus
A new study shows that PFAS influence the cellular immune response to coronavirus and also reveals sex-specific differences as to how the immune system reacts to the virus.
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Discovery opens up for new ways to treat chlamydia
Researchers have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health.
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$2.7 million NIH grant to fund first comprehensive syphilis test
With a four-year, $2.7 million grant from NIAID, researchers aim to develop a one-step confirmatory laboratory test that can definitively diagnose active syphilis infection within 10 minutes.
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Gut microbes release cancer-fighting bile acids that block hormone signals
Bacteria naturally present in the human intestine can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study.
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Potential first new antibiotic for gonorrhoea since the 1990s is effective and safe, finds trial
Gepotidacin could be a new treatment to treat gonorrhoea, protecting against the threat of treatment-resistant gonorrhoea and improving patient treatment experiences, suggests the results of a phase 3 randomised control trial.
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Parasitic infection and treatment linked to cancer-related gene activity in the cervix
New research has revealed that Schistosoma haematobium, a parasitic infection affecting millions globally, can trigger cancer-related gene activity in the cervical lining, with changes becoming even more pronounced after treatment.
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New antibiotic for multidrug resistant superbug triggers suicide mechanism
Researchers have discovered a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhoea.
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FAU secures $1.3 million NIH grant for breakthrough in HIV self-test technology
To address the urgent need for a reliable, rapid and affordable self-test for early HIV detection, researchers have been awarded phase-II of a five-year, $1.3 million grant which will support the development of an innovative disposable microchip technology designed for HIV-1 self-testing during the first two weeks post-infection.