All University College London articles
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COVID-19 could hold key to spotting viruses with pandemic potential
Certain SARS-CoV-2 variants of concern are evolving to do a better job of shutting down human innate immune responses, according to new research.
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Monitoring bats can help ID coronaviruses with pathogen potential
Researchers who found novel coronaviruses in UK bats say genetic surveys of the viruses should be regularly conducted, even if none of those viruses can infect humans yet.
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Mapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
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Newborns worldwide dying from sepsis as antibiotics lose their bite
A global observational study involving more than 3,200 newborn babies suffering from sepsis in 11 countries has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness.
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Trial aims to improve treatment for newborns with sepsis
An international clinical trial will evaluate much-needed new antibiotic combinations for newborn babies with life-threatening sepsis.
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UK vaccine and food manufacturing hubs will save lives and cut carbon
Two initiatives, an investment of £24 million, will help the UK lead the world in preparedness for pandemics and epidemics, and in delivering secure food supplies.
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Genomic surveillance may track evolution of emerging wheat disease fungus
Genomic surveillance may be an effective disease management tool against the wheat blast pandemic, with the ability to trace lineages of emerging crop diseases, and to identify genetic traits for breeding disease-resistant lines, a study suggests.
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Hidden Nsp1 cavity means Covid’s Spike protein is no longer the only target
Researchers have revealed the existence of a hidden ’’pocket’ on the surface of the non-structural protein Nsp1 on the surface of the Covid-19 virus which could offer a potential drug target and alternative to the Spike protein targeted by vaccines.
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Gram-negative bacteria build outer membrane into body armour-like structure
A new study has shed light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armour, which has far-reaching implications for the development of antibiotics.