All University of Cambridge articles
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Cambridge initiative to address risks of future engineered pandemics
Management strategies are initiated by University of Cambridge to address the challenges and preventive measures required in response to a potential engineered pandemic threat in the future.
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New 3D imaging approach reveals intricate steps of virus assembly
A new integrated 3D imaging approach combines cryo-light microscopy and cryo-soft X-ray tomography to reveal the intricate ultrastructure of herpes simplex virus-1 (HSV-1) assembly.
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Feeding your good gut bacteria through fibre in diet may boost body against infections
Researchers who used computational approaches to analyse the gut microbiome composition of over 12,000 peoplefrom their stool samples found that a person’s microbiome ‘signature’ can predict whether their gut is likely to be colonised by Enterobacteriaceae.
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System to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.
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A team of scientists join forces for the fight against deadly childhood disease
A global consortium of scientists has been tasked with better understanding the scale of Shigella infections and the role of antibiotic resistance in seven countries.
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Better together: Gut microbiome communities’ resilience to drugs
Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome. EMBL Heidelberg researchers have now discovered that this effect is reduced when bacteria form communities.
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Monoclonal antibodies offer hope for tackling antimicrobial resistance
Monoclonal antibodies – treatments developed by cloning a cell that makes an antibody – could help provide an answer to the growing problem of antimicrobial resistance, say scientists.
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Report recommends ‘highly ambitious enterprise’ to create world-leading UK Microbiome Biobank
A new report calls for a ’highly ambitious enterprise’ to create a microbiome biobank that will contribute significantly to the advancement of science and its application to human health.
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Incidence of heart attacks and strokes found to be lower after COVID-19 vaccination
A new study involving nearly the whole adult population of England has found that the incidence of heart attacks and strokes was lower after COVID-19 vaccination than before or without vaccination.
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Next generation biosensor reveals gibberellin’s critical role in legume nitrogen-fixation
Researchers have identified the specific times and location where gibberellin (GA governs) the initiation, growth and function of nitrogen-fixing root nodules.
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Scientists ID bacterial genes that yield iridescent colors
Scientists sequenced the DNA of 87 structurally colored bacteria and 30 colorless strains and identified genes that are responsible for iridescent bacterial colonies.
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AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, researchers have shown. An algorithm can be trained to identify drug-resistant bacteria correctly from microscopy images alone.
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Scientists map how deadly bacteria evolved to become epidemic
Pseudomonas aeruginosa evolved rapidly and then spread globally over the last 200 years, probably driven by changes in human behaviour, a new study has found.
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Mobile phone data helps track pathogen spread and evolution of superbugs
Combining genomic data and human travel patterns over a 14-year period in South Africa reveals key insights into the spread, evolution and resistance patterns of a major bacterium behind pneumonia and meningitis globally.
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Statisticians call for rigour and transparency in the evaluation of diagnostic tests
Recommendations designed to reframe the evaluation of in vitro diagnostic tests have been published - intended to help prevent future scenarios in which IVDs are marketed widely, but later attract serious concerns about the standards applied to their evaluation.
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Birth by C-section more than doubles odds of measles vaccine failure
Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the disease.
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New vaccine effective against coronaviruses that haven’t even emerged yet
Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks - including ones we don’t even know about.
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Source of pregnancy complications from infections revealed by placenta map
The first panoramic view of infection pathways in the human placenta has been created, which could highlight potential drug targets to develop pregnancy-safe therapies for malaria, toxoplasmosis and listeria.
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TB vaccine may enable elimination of the disease in cattle by reducing its spread
Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds.
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New and highly infectious E. coli strain resistant to powerful antibiotics
A more infectious version of the bacterium is found to have caused two outbreaks in a children’s hospital in China.