All University of Hong Kong articles
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Scientists unveil viral mechanism behind nasopharyngeal cancer spread
Researchers have discovered that the Epstein-Barr virus (EBV), a common human virus closely linked to nasopharyngeal carcinoma (NPC), can change the 3D structure of the human genome inside cancer cells, much like assembling building blocks.
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World’s first AI system for single-tooth prediction of early childhood caries detection with over 90% accuracy
Scientists have developed the world’s first artificial intelligence (AI) system capable of predicting early childhood caries risk for individual teeth based on microbial characteristics, achieving an accuracy rate of over 90%.
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Scientists discover key protein that enables ‘shock & kill’ strategy for HIV latent virus clearance
Researchers have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.
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Researchers pioneer novel, needle-free, live-attenuated influenza vaccines with broad protection
Researchers have achieved a significant breakthrough in developing broadly protective, live-attenuated influenza vaccines (LAIV).
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Researchers reveal how human genetics and intratumoral microbiota affect colorectal cancer
A study shows that the single-nucleotide polymorphism (SNP) rs2355016—a tiny DNA change that some people carry—affects how intratumoral microbiota adhere to tumor cells, promoting colorectal cancer progression.
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Global study finds single-dose baloxavir reduces household influenza transmission
A landmark study reveals that a single oral dose of baloxavir marboxil (baloxavir) significantly reduces the transmission of influenza within households, marking a major advancement in influenza management.
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Researchers develop innovative solution for tracking antibiotic resistance genes
Scientists have developed a computational tool, Argo, designed to accurately track ARGs in environmental samples, providing insights into their dissemination and associated risks.
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Oral microbiota offer promise as screening tool for young children with autism spectrum disorder (ASD)
Scientists have found promising connections between oral microbiota and autism spectrum disorder (ASD). Their study introduces a prediction model with an 81% accuracy rate for identifying children with autism through simple oral sampling.
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Scientists develop nasal spray H5N1 avian influenza vaccine
Scientists have pioneered an influenza virus vector-based nasal spray vaccine platform and developed a nasal spray H5N1 avian influenza vaccine.
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Lactobacillus-dominated uterus significantly boosts pregnancy outcomes
Researchers analyzed recent studies on the reproductive microbiome and its effects on fertility. They found that a Lactobacillus-dominated (LD) uterine environment significantly improves pregnancy outcomes. Similarly, pregnancy success rates were higher in LD environments.
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Study links high-risk Epstein-Barr virus lineage to nasopharyngeal cancer in southern China
Researchers have discovered a significant association between specific Epstein-Barr virus (EBV) variants and nasopharyngeal carcinoma (NPC), a cancer prevalent in southern China, where it is 20 times more common than in non-endemic regions of the world.
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Sludge sequencing reveals novel species and genetic diversity
A study sequencing activated sludge has unearthed a plethora of antibiotic resistance genes and has pointed to the existence of previously unknown microbial species.
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Scientists ID novel host factors that facilitates SARS-CoV-2 entry
Researchers have identified new host factors that interact with the receptor binding domain of the SARS-CoV-2 spike protein to promote viral entry.
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Study shows N95 masks near-perfect at blocking escape of airborne COVID-19
In a head-to-head comparison of masks worn by people with active COVID-19, the inexpensive ‘duckbill’ N95 came out on top, stopping 98% of COVID-19 particles in the breath of infected people from escaping into the air.
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Optimal timing maximises Paxlovid benefits for treating COVID-19
Study suggests using the anti-COVID-19 treatment Paxlovid three to five days after symptoms emerge in patients and expanding global access to the drug may help reduce the severity and transmission of the SARS-CoV-2 virus.
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PD-1-enhanced DNA vaccine achieves 6-year cART-free AIDS prevention and virologic control
Researchers have found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model.
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New institute to bolster global preparedness for future pandemics
The University of Hong Kong (HKU), the University of Cambridge (UCAM), and the International Vaccine Institute (IVI) have established the international headquarters of The Hong Kong Jockey Club Global Health Institute at HKU.
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Scientists find genes in gut microbes that help to alleviate constipation
Researchers have found that probiotic Bifidobacteria longum strains possessing the abfA cluster of genes can ameliorate constipation through enhanced utilization of an indigestible fiber called arabinan in the gut.
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New antibiotic drug approved for clinical trials in humans
A new antibiotic drug has recently gained approval from the authorities to undergo clinical trials.
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Scientists pioneer dual trojan horse approach to combat superbugs
In the relentless battle against antibiotic-resistant superbugs, science continues to unveil ingenious strategies to address their vulnerability. Like other bacteria, superbugs have a unique weakness – their dependence on iron for growth and survival. Iron serves as an essential nutrient that bacteria utilise for various cellular processes, including DNA replication, ...