All Weill Cornell Medicine articles
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Study discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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Designing self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens the door to new treatments.
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Study uncovers new pathway controlling levels of body fat and cholesterol
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study.
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Study untangles how COVID-19 wreaks widespread damage in the body
A new study sheds light on the pathways that drive organ damage and death in severe COVID-19 and helps explain why survivors of the disease can experience long-term complications.
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Mouse gut fungus reveals secrets of symbiosis and allergy
A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research. The finding suggests that preclinical studies until now have overlooked a major influencer of mouse physiology.
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$5.6 million grant awarded to target treatments for IBS, Crohn’s and Ulcerative colitis
An “out-of-the-box” study has been awarded a $5.6 million NIH grant to target treatments for IBS, Crohn’s, Ulcerative Colitis and more.
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Could a bout of COVID protect you from a severe case of flu?
More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different one?
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Antiviral-resistant variants of SARS-CoV-2 can emerge in immunocompromised people
Individuals with compromised immunity and persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread to the general population.
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NIH funds consortium to accelerate development of new TB treatments
A new consortium has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis.
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Study backs RSV vaccine safety during pregnancy
Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a new study.
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New lab test to detect persistent HIV strains in Africa may aid search for cure
A multinational team has developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.
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Gut microbiota acts like an auxiliary liver
Microbes in the mammalian gut can significantly change their hosts’ amino acid and glucose metabolism, acting almost like an extra liver, according to a new preclinical study.
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Drug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy
Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens.
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SARS-CoV-2 can infect dopamine neurons, causing senescence
A new study has reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence - when a cell loses the ability to grow and divide.
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CRISPR-based drug candidate targets the microbiome
Scientists have engineered the first published CRISPR-based candidate for a drug - a combination of phages - that targets E. coli directly and leaves the microbiome intact.