All One Health Content – Page 171
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Viruses that kill cancer cells show promise for triple-negative breast cancer when combined with chemo
Researchers have shared positive results from a phase 2 clinical trial of an oncolytic virus combined with standard chemotherapy in patients with early stage triple-negative breast cancer.
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Study IDs bacterial weapons that could be harnessed to treat human disease
The discovery of ancient immune-fighting machinery in human cells that is derived from bacteria paves the way toward more ‘CRISPR’-like technologies, researchers say.
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Electrochemical energies yield insights into how bacteria may develop antibiotic tolerance
Researchers investigated variations in the electrochemical energies that power bacterial growth to understand how bacteria develop antibiotic tolerance without acquiring new genes or mutating existing ones.
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Two Chinese anti-SARS-CoV-2 drugs conditionally approved for marketing
Two innovative Chinese oral anti-SARS-CoV-2 drugs, Xiannuoxin (simnotrelvir/ritonavir) and VV116 (deuremidevir hydrobromide), were conditionally approved for marketing by China’s National Medical Products Administration (NMPA) in late January after urgent review and approval under the Special Examination and Approval of Drugs Policy.
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Funding backs world-first test to detect ‘insidious’ malaria infections
Research to develop and deploy a world-first diagnostic test that could accelerate malaria eradication has been bolstered with over $1.3 million in new funding from the National Health and Medical Research Council (NHMRC) in the US.
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E coli strain may have evolved too far to be fit for lab purposes
A model organism used in laboratories for the past 100 years has evolved so extensively that it may no longer be fit for purpose, according to a new study.
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Deadly Keanu-inspired bacterial compound delivers excellent anti-fungal protection to plants
Researchers have proved that an antimicrobial natural product produced by Pseudomonas - and named after Keanu Reeves - is effective against both plant fungal diseases and human-pathogenic fungi.
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ME linked to changes in the gut microbiome and metabolites
Two studies have found that myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is associated with reduced levels in the gastrointestinal microbiome of microbes known to produce the fatty acid butyrate, disruptions that could explain in part how the immune system becomes disrupted in people with ME/CFS.
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Diagnostic technique IDs five key AMR markers in water samples in less than an hour
A new testing method can detect five key antimicrobial resistance markers in water samples in less than an hour.
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New inoculation based on Ebola VSV vaccine concept protects macaques
Researchers have successfully developed a vaccine against Sudan virus (SUDV) based on the licensed Ebola virus (EBOV) vaccine.
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Harmful bacteria can elude predators when concealed in mixed colonies
Efforts to fight disease-causing bacteria by harnessing their natural predators could be undermined when multiple species occupy the same space, a new study has revealed.
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Youth binge drinkers show alterations in the gut microbiome, new study finds
A study of young people found that alterations in the gut microbiome, microorganisms that live in the human digestive system and affect health, are linked with binge drinking in young people.
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New antibiotic lunaemycin extracted from moonmilk deposits in caves
Scientists investigating moon milk - a mineral deposit found in caves and used for its curative properties - has led to the discovery of a cryptic compound active against bacteria that are multi-resistant to antibiotics.
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Increase in multidrug-resistant pathogens since Ukraine war
Researchers in Germany have recommended screening patients from Ukraine for multi-drug resistant pathogens prior to hospital admission following a series of outbreaks.
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Scientists discover unknown circovirus involved in human hepatitis
Scientists have identified a previously unknown species of circovirus, provisionally named human circovirus 1 (HCirV-1).
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Quail could be mystery reservoir for Tuscany and Sicilian viruses
The quail could be the unknown reservoir of the Toscana virus (TOSV) and the Sandfly Fever Sicilian virus (SFSV), mosquito-borne pathogens that can infect domestic animals and also cause disease in humans.
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Researchers create tool to map Mexico’s dengue fever hotspots
Researchers have analyzed data from Mexico’s Ministry of Health to identify dengue fever hotspots, calculating environmental and socioeconomic risk factors and mapping areas where severe outbreaks occur.
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Researchers create ‘undercover agent’ tool to track bacterial assassins in real time
Researchers have developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells and which can be used to investigate bacterial interactions with the host in real-time during an infection.
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Regulatory pathway needs to be developed to make the most of phages: AMI
A regulatory pathway needs to be developed if the UK is to reap the benefits of bacteriophage therapy, Applied Microbiology International (AMI) has warned. France, Belgium and Poland are already developing programmes that take advantage of the potential of phage therapeutics, while bacteriophages - viruses that are capable of destroying ...
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Scientists find two separate reservoirs of latent HIV in patients
Scientists have shown that, addition to HIV’s ability to lay dormant in the blood/lymphoid system, the virus may also lay dormant in the central nervous system, delineating another challenge in creating a cure.