All One Health Content – Page 27
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Scientists synthesize a promising mushroom-derived compound
Researchers have successfully developed the first method to synthesize inaoside A, a compound derived from the edible mushroom Laetiporus cremeiporus.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Human papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
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Biotin may shield brain from manganese-induced damage, study finds
New research showing the mechanisms by which manganese inflicts damage to the central nervous system suggests that the vitamin biotin - synthesized by gut bacteria - may have a protective effect, potentially mitigating manganese-induced damage.
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A Marburg virus outbreak was confirmed in Tanzania
WHO has announced that an outbreak of Marburg virus disease in Tanzania has been confirmed, with 25 suspected cases. Outbreak control measures have been established since the announcement.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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WHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
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Ancient viral DNA shapes early embryo development
Over half of our genomes consists of remnants of ancient viral DNA which are widespread across the tree of life. Once dismissed as the ’dark side’ of the genome, researchers have now revealed the role of transposable elements in early embryo development.
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Valneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
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Research team receives $1.5 million to study neurological disorders linked to long COVID
A significant grant was awarded for an upcoming research of cellular and molecular mechanisms in the neurological challenges posed by long COVID-19.
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Tiny vortices help detect dangerous viruses
Due to the specific wavelengths of vibrations used to create these tiny whirlpools, they efficiently trap cells, bacteria and other larger bioparticles found in saliva while leaving antibodies and viruses free to flow forward through multiple biosensing chambers.
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Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A promising research study in treating high mortality late-stage cancers with a non-toxic bacterial therapy - BacID - has proven to be safe and more targeted. The newly developed treatment would undergo clinical trials with cancer patients in 2027.
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Sophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.
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Bacteria in polymers form cables that grow into living gels
Scientists have discovered that bacterial cells growing in a solution of polymers, such as mucus, form long cables that buckle and twist on each other, building a kind of “living Jell-O.”
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Extreme rain heightens E. coli risks for communities of color in Texas
New research shows that communities of color in Texas face pronounced risks of E. coli exposure in nearby waters following storms that dump abnormally high amounts of rain.
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Bioactive compounds with possible industrial applications are identified in extremophilic bacteria from the Andes
Researchers isolated a strain of Pseudomonas alcaligenes that can withstand temperatures as high as 44 °C from a hot spring in Chile, and characterized the substances produced by the bacterium that help it survive extreme conditions.
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Oral cancer and microbiome: new insights into tumor growth mechanisms
A recent study has made significant strides in uncovering how the oral microbiome plays a crucial role in the progression of oral squamous cell carcinoma (OSCC), unveiling metabolic pathways and mechanisms that may serve as potential therapeutic targets.
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Effectiveness and safety of tenofovir amibufenamide in the treatment of chronic hepatitis B: A real-world, multicenter study
A new study aimed to evaluate the real-world effectiveness and safety of tenofovir amibufenamide (TMF) in a cohort of patients with chronic hepatitis B (CHB).