All antimicrobial peptides articles
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NewsNew source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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NewsReal-time 3D visualization of leech peptide reveals potent antibacterial and antibiofilm activity
Researchers have discovered a novel natural antimicrobial peptide, ‘Hirunipin-2,’ from the salivary glands of the medicinal leech using cutting-edge imaging technology, demonstrating that it has high potential as a new therapeutic effective against superbacteria.
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FeaturesParasitic worms: an unexplored source of novel antimicrobials?
Novel antimicrobials are desperately needed to combat the AMR crisis, however, the clinical and preclinical pipeline for novel antimicrobials is virtually stagnant. This article will shed light on parasitic worms as an unexplored and underappreciated source of antimicrobial peptides.
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NewsResearchers find new defense against hard-to-treat plant diseases
Scientists have developed a new approach to countering citrus greening and potato zebra chip diseases. Their method uses spinach antimicrobial peptides, known as defensins, which naturally defend plants.
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NewsBarriers remain to peptide-based therapies - but there are answers, reveals study
Peptide-based therapies offer the potential to transform how we treat a range of conditions - but have yet to be adopted for widespread clinical use. A new review uncovers the barriers to adoption and identifies ways to overcome these limitations.
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NewsFungus ‘hacks’ natural immune system causing neurodegeneration in fruit flies
A fungus, called Beauveria bassiana, is found to manipulate the innate immunity of the fruit flies to attack their own brain cells, causing the penetration into the blood-brain barriers and eventually neurodegeneration.
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NewsWe know what you ate: Detailed protein maps assess intestinal health
A new method has been designed to map the near-exact molecular details of the human and bacterial protein regulations within the host-gut microbiome interactions. These proteins could be used for medical and dietary intervention to maintain intestinal health.
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NewsAI opens door to safe, effective new antibiotics to combat resistant bacteria
A large language model—an AI tool like the one that powers ChatGPT—has been used to engineer a version of a bacteria-killing drug that was previously toxic in humans.
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NewsTreatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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NewsAntimicrobial peptides modulate lung injury by altering the intestinal microbiota
Researchers have identified a gut-lung axis driven by intestinal antimicrobial peptide expression and mediated by the intestinal microbiota that is linked to lung injury in newborns.
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NewsAntimicrobial use in agriculture can breed bacteria resistant to first-line human defences
A new study has shown that overuse of antimicrobials in livestock production can drive the evolution of bacteria more resistant to the first line of the human immune response.