All Aspergillus fumigatus articles
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How fungi strengthen their defenses - and how we could break through them
A research team has discovered that the enzyme Mod5 in the fungus Aspergillus fumigatus plays an important role in the modification of fungal tRNA and helps confer temporary antifungal resistance.
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Deadly mould strains highly likely to acquire resistance to new drugs
Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also five times more likely to acquire resistance to desperately needed new treatments in development. Source: Ufficio Comunicazione, Azienda Ospedaliera SS. Antonio e ...
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Historic outbreaks of coffee wilt disease linked to gene transfer from another fungus
The fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease.
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Enzyme produced by pathogenic fungus helps evade immune system and facilitates infection
Researchers found 62 proteins specific to spores of Aspergillus fumigatus, a fungal species that causes lung disease. The study showed that at least one of these proteins inhibits human human defense mechanisms.
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Researchers discover key gene regulating virulence of fungus that causes severe lung infections
Scientists have found a potential target for novel therapeutic strategies to combat fungal infections caused by Aspergillus fumigatus and are now looking for a molecule that inactivates the protein expressed by the gene as a basis for a drug.
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Fungi elude antifungal treatments by restructuring cell walls
A new multi-institutional study has characterized how fungi adapt to restructure their cell walls, effectively thwarting current antifungal medications. This new information opens opportunities to devise more effective use of antifungal drugs.
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Multidrug-resistant fungi found in commercial soil, compost and flower bulbs
A study has found high levels of multidrug-resistant fungi in commercially available compost, soil and flower bulbs. Named a critical public health threat by WHO, Aspergillus fumigatus is potentially deadly to immunocompromised people.
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Scientists unlock the secrets of disease-causing fungus Aspergillus fumigatus
A new study demonstrates the pivotal role of the Mitogen-Activated Protein kinase MpkA in both gliotoxin production and self-protection.
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Researchers shed light on how one deadly pathogen makes its chemicals
Scientists have deciphered a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, whose family causes Aspergillosis in humans.
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Statins team up with azoles to battle fungal infections
Researchers evaluated the antifungal efficacy of the pitavastatin-azole combination in silkworm models, suggesting its potential as an effective clinical treatment.
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Drugs targeting iron regulation could be the answer to antifungal resistance
Drugs targeting iron uptake mechanisms could prove vital in the fight against human fungal pathogens, a new review suggests.
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Deadly fungus beaten with treatment blocking fatty acid formation
Researchers have discovered a new way to attack fungal infections by blocking fungi from being able to make fatty acids, the major component of fats.
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Drug-resistant fungi thriving in the most remote regions of Earth
New research has found that a disease-causing fungus — collected from one of the most remote regions in the world — is resistant to a common antifungal medicine used to treat infections.
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Fungal spores bind to lung cell protein to escape human defences
The pathogenic fungus Aspergillus fumigatus escapes elimination from surface cells of the human lung by binding to a human protein.