All Case Western Reserve University articles
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News
Signs of life on Mars? Not so fast, say geologists
Geologists have urged caution in claiming signs of life on Mars from speckled rock found by Perseverance Rover. The researchers believe that a non-biological origin of the speckled rock found on Mars by NASA’s Perseverance rover is just as compelling as a biological one.
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Evolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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Bacteria invade brain after implanting medical devices
Researchers have discovered that bacteria can invade the brain after a medical device is implanted, contributing to inflammation and reducing the device’s long-term effectiveness.
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Herpesviruses may contribute to Alzheimer’s disease via transposable elements
Researchers have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer’s disease in aging brains, and also share two FDA-approved, commercially available drugs that reverse this pathway in a laboratory setting.
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New discovery provides hope in fighting drug-resistant malaria
Researchers have described how they may have found a new target in Plasmodium falciparum, the deadliest malaria parasite: a cholesterol-managing protein called PfNCR1.
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Novel antibody platform tackles viral mutations
Scientists have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.
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Scientists probe mechanics of how bacteria and antibiotics interact down to molecular level
Scientists exploring how combinations of antibiotics can fight resistant bacteria have been awarded an $11.8 million grant for work that could help save the tens of thousands of lives lost yearly to infections that are increasingly plaguing humanity.
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Researchers a step closer to a cure for HIV
A new study demonstrates that a patented therapeutic candidate, an HIV-virus-like-particle (HLP), is 100 times more effective than other candidate HIV cure therapeutics for people living with chronic HIV on combined antiretroviral therapy (cART).
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Unraveling cell death protein may inspire new biotechnology tool
Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool. The protein belongs to the ‘superfamily’ of Argonaute proteins, which previous research has suggested ...
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‘Antibiotic culture’ permeates US hospital ICUs, study finds
A new study reveals that there continues to be an ’antibiotic culture’ in US hospitals, meaning that the preference for antibiotics is related to their perceived role as ’magic bullets’.