All fluconazole articles
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NewsAntifungal therapy shows potential for IBD patients with candida overgrowth
A commonly used systemic antifungal medication may help reduce symptoms in a subset of patients with inflammatory bowel disease (IBD) by restoring a healthier gut microbiome, according to a preliminary study.
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NewsZinc deficiency promotes fluconazole-resistant Candida auris virulence
Researchers identified key nutritional and genetic factors that drive the virulence of fluconazole-resistant Candida auris. Under zinc-deficient conditions, these drug-resistant strains gain a fitness advantage, exhibiting increased pathogenicity and resistance to macrophage-mediated killing.
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NewsAgricultural azoles drive clinical azole resistance in Candida tropicalis via inducing aneuploidy
To define the causal role of agricultural azole fungicides in driving clinical azole resistance in the major human opportunistic fungal pathogen Candida tropicalis, researchers conducted a systematic study integrating experimental evolution, genomic characterization, and transcriptomic profiling.
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NewsPolicy change may be helping to drive rise in treatment-resistant vaginal thrush
A change in policy may be helping to drive a rise in treatment-resistant vaginal thrush, amid significant yearly increases in the prevalence of fungal infections caused by fungal Candida species, suggests the first study of its kind.
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NewsBone loss drugs can help azoles fight fungal infections
A new study suggests that adding common bone loss drugs to azoles can improve efficacy. In lab tests, combinations of these drugs worked against dermatophyte species and prevented resistance.
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NewsThe world’s most powerful anti-fungal chemistries cause fungal pathogens to self-destruct
Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
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NewsKeto diet boosts lifesaving antifungal drug in mice
In animal tests, researchers have found that taking fluconazole in combination with a low-carb, high-fat keto diet worked significantly better at killing the fungus behind fungal meningitis than taking the medication alone.
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NewsResistant Candida auris on rise in Germany, setting off alarm signals
The number of cases of Candida auris has increased in Germany in recent years, adding to outbreaks worldwide, a new study has revealed.
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NewsFull ICUS and abuse of meds sparked post-pandemic outbreak of drug-resistant fungus in Brazil
Researchers in Brazil have reported the largest outbreak to date of COVID-associated candidemia caused by the same drug-resistant strain of Candida parapsilosis, a fungus that invades the bloodstream and can lead to death.