All herpes simplex virus articles
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NewsHerpes virus fluidizes cell nuclei to multiply faster
A new study finds that herpes simplex virus uses a protein called infected cell protein 4 (ICP4) to make the human nucleus more fluid-like, which in turn makes it easier for the virus to replicate itself. Blocking the ability of ICP4 to fluidize the nuclear compartment caused a drop in viral copy production.
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NewsVirus-based therapy boosts anti-cancer immune responses to brain cancer
A study has shown that a single injection of an oncolytic virus—a genetically modified virus that selectively infects and destroys cancer cells—can recruit immune cells to penetrate and persist deep within brain tumors.
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NewsMajor clinical trial provides definitive evidence of impacts of steroid treatment on severe brain infection
A major UK clinical trial has shown that adding the corticosteroid dexamethasone to standard antiviral treatment for encephalitis, caused by herpes simplex virus (HSV) does not improve long-term outcomes overall, although early use may lead to better recovery.
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NewsEngineered virus boosts immune response against glioblastoma in preclinical models
Researchers have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and myeloid cell responses in the tumor microenvironment and increased the overall survival in preclinical models.
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NewsNeonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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NewsAround 1 in 5 of the world’s under 50s living with genital herpes (HSV)
Around 1 in 5 of the world’s under 50s—846 million people—are living with genital herpes infection, and more than 200 million 15-49 year olds probably had at least one symptomatic outbreak of the infection in 2020, suggest the latest global estimates.
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NewsWhat enables herpes simplex virus to become impervious to drugs?
Research pinpoints the key to the cold sore virus’s ability to evade treatment, offering broader clues on antiviral drug resistance.
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NewsFusion protein reveals a conservative antigenic domain across herpesviruses
A new study proposes that the gB DII domain within the herpesvirus family constitutes a broadly conserved neutralizing epitope structural domain.
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NewsDouble risk of dementia after mouth ulcer virus
People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected.
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NewsResearchers offer new insights into how antibodies function against HSV
Findings from a new study offer insights into how antibodies function in combating herpes simplex virus (HSV) infections. Their research may lead to possible new treatments for neonatal herpes.
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NewsStudy reveals how the immune system fights to keep herpes at bay
A recent study, conducted using lab-engineered cells, unveils the precise maneuvers used by host and herpes simplex virus (HSV) in the fight for dominance of the cell.