All Johns Hopkins University articles
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Novel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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Could we engineer stability in the microbiome? New research opens the door
New work could revolutionize our understanding of how the composition of the gut microbiome is determined and open the door to microbiome engineering.
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Study untangles how COVID-19 wreaks widespread damage in the body
A new study sheds light on the pathways that drive organ damage and death in severe COVID-19 and helps explain why survivors of the disease can experience long-term complications.
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Global antibiotic consumption has increased by more than 21 percent since 2016
An analysis of antibiotic sales data from 67 countries from 2016-2023 shows a decrease in consumption in high-income countries countered by an increase in middle-income countries.
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Extreme microbe reveals how life’s building blocks adapt to high pressure
An AI tool has helped scientists discover how the proteins of a heat-loving microbe respond to the crushing conditions of the planet’s deepest ocean trenches, offering new insights into how building blocks of life might have evolved under early Earth conditions.
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Recreational tubing and swimming leave microbial impact on streams
Researchers found that swimming and tubing on a Colorado creek over a busy Labor Day weekend can have a short-term effect, increasing the levels of metals, human gut-associated microbes and substances from personal care products.
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Long Covid continues to evade diagnosis
A national cohort study of adult US participants with and without prior SARS-CoV-2 infection found that there are no objective tests to accurately diagnose post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long Covid.
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Scientists probe molecular cause of COVID-19 related diarrhea, revealing potential treatments
Working with human stem cells that form a kind of ’mini intestine-in-a-dish’, scientists say they have found several molecular mechanisms for COVID-19-related diarrhea, suggesting potential ways to control it.
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Future enterovirus outbreaks could be exacerbated by climate change
A common set of drivers can explain the timing of outbreaks of both hand, foot and mouth disease and polio, according to a recent study which suggests these summertime outbreaks may hint at implications for climate change.
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New lab test to detect persistent HIV strains in Africa may aid search for cure
A multinational team has developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.
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Women need better treatments for bacterial vaginosis: call
Researchers at the University of Maryland School of Medicine are calling for robust studies for a treatment already used in Europe.
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Insights from patient who cleared hepatitis C could lead to vaccine
By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.
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AI can now detect COVID-19 in lung ultrasound images
Artificial intelligence can spot COVID-19 in lung ultrasound images much like facial recognition software can spot a face in a crowd, new research shows.
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New method identifies bacteria more easily
Scientists have developed a simple tool that can identify all of the genetic material in bacteria.
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Genetic fingerprint suggests cutaneous leishmaniasis may be gaining foothold in US
Analysis reveals DNA evidence of a US-acquired strain of cutaneous leishmaniasis - the prospect of a growing threat comes amidst concerns that domestic sand flies could acquire a deadly form of the disease via dog imports.
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Tubing and swimming change the chemistry and microbiome of streams
Scientists have reported preliminary results showing that tubing and swimming can alter the chemical and microbial fingerprint of streams, but the environmental and health ramifications are not yet known.